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Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment.
At last! https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/117982-repurposing-screen-identifies-mebendazole-as-a-clinical-candidate-to-synergise-with-docetaxel-for-prostate-cancer-treatment.html
At last! https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/117982-repurposing-screen-identifies-mebendazole-as-a-clinical-candidate-to-synergise-with-docetaxel-for-prostate-cancer-treatment.html
kryciakrycia
in
Advanced Prostate Cancer
5 years ago
Patient rep needed for PhD study on peripheral neuropathy (London area)
Hello All Mary Tanay, a nurse at Kings College Hospital in London, is writing her PhD study on Chemotherapy Induced Peripheral Neuropathy (CIPN). A summary of the study can be found via this link: https://www.fundingawards.nihr.ac.uk/award/DRF-2018-11-ST2-017 Mary is looking to recruit another 2-3
Hello All Mary Tanay, a nurse at Kings College Hospital in London, is writing her PhD study on Chemotherapy Induced Peripheral Neuropathy (CIPN). A summary of the study can be found via this link: https://www.fundingawards.nihr.ac.uk/award/DRF-2018-11-ST2-017 Mary is looking to recruit another 2-3
OvacomeSupport
Administrator
in
My Ovacome
5 years ago
Burning in feet
I have small fibre neuropathy in my feet and the burning is unbearable. It is 24/7 and I was wondering if anyone else has this and what medication you take that helps with the burning. I really do not like taking medications because of the side effects but I am desperate now. Thank you
I have small fibre neuropathy in my feet and the burning is unbearable. It is 24/7 and I was wondering if anyone else has this and what medication you take that helps with the burning. I really do not like taking medications because of the side effects but I am desperate now. Thank you
Karjade
in
Pain Concern
5 years ago
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Hello everyone I have had on going symptoms of pins and needles in my legs and muscle fasculations for the last year. Every single doctor had cleared me, including neurologist. My nerve tests came back fine, in Australia we can't do sfn tests so they rely on the neurological examination. What I really
Hello everyone I have had on going symptoms of pins and needles in my legs and muscle fasculations for the last year. Every single doctor had cleared me, including neurologist. My nerve tests came back fine, in Australia we can't do sfn tests so they rely on the neurological examination. What I really
confused1990
in
Neuropathy Support
5 years ago
Numbness and pins and needles!
Hi all! Hope everyone had a restful xmas and new year! Bit of a query, over the last 3 months I've noticed my hands go numb and/or tingly randomly, usually lasts between 5- 20 minutes and there doesnt appear to be a pattern however it is getting more frequent. Does anyone know if this is a fibro
Hi all! Hope everyone had a restful xmas and new year! Bit of a query, over the last 3 months I've noticed my hands go numb and/or tingly randomly, usually lasts between 5- 20 minutes and there doesnt appear to be a pattern however it is getting more frequent. Does anyone know if this is a fibro
jpowe
in
Fibromyalgia Action UK
5 years ago
Tingling feet
For many years I have had pins and needles in my feet. Drs haven’t been interested, but lately the feeling has spread up my shins and my hands also tingle. The soles of my feet feel as if they are on fire. Today’s Dr, yet another locum was at a loss. My B12 and D3 are fine, no sign of diabetes. Does
For many years I have had pins and needles in my feet. Drs haven’t been interested, but lately the feeling has spread up my shins and my hands also tingle. The soles of my feet feel as if they are on fire. Today’s Dr, yet another locum was at a loss. My B12 and D3 are fine, no sign of diabetes. Does
Hidden
in
Thyroid UK
5 years ago
Magnesium... what dosage and any recommendations for brand?
Happy new year guys! I’ve been taking my levo around 5weeks now, I’ve introduced vitamin c and vitamin d spray but didn’t want to do everything at once, I now feel ready to add another which ideally needs to be magnesium to aid absorption of the d3 I believe. I’ve read some links which were kindly posted
Happy new year guys! I’ve been taking my levo around 5weeks now, I’ve introduced vitamin c and vitamin d spray but didn’t want to do everything at once, I now feel ready to add another which ideally needs to be magnesium to aid absorption of the d3 I believe. I’ve read some links which were kindly posted
Rosie2m
in
Thyroid UK
5 years ago
Hello! New member
Hello! I'm seeking some advice. I have had these odd symptoms for over a year now and my neurologist has said it sounds like RLS. However I have doubts as I've looked at the criteria and don't seem to fulfill all of it. I have pins and needle/legs in my feet, hand and legs all day everyday. It started
Hello! I'm seeking some advice. I have had these odd symptoms for over a year now and my neurologist has said it sounds like RLS. However I have doubts as I've looked at the criteria and don't seem to fulfill all of it. I have pins and needle/legs in my feet, hand and legs all day everyday. It started
confused1990
in
Restless Legs Syndrome
5 years ago
Current mental health status
I also tried
naturopathy
but i didnt feel any different .
I also tried
naturopathy
but i didnt feel any different .
Mia_love
in
Anxiety and Depression Support
5 years ago
NEUROPATHY?
I have neuropathy. The bottom of my feet get numb. What worries me a little is that sometimes my tremor side left foot turns purple from time to time. Has that happened to any of you? If so, what do you do to relieve the problem? Thanks for your help!
I have neuropathy. The bottom of my feet get numb. What worries me a little is that sometimes my tremor side left foot turns purple from time to time. Has that happened to any of you? If so, what do you do to relieve the problem? Thanks for your help!
shanaandbear
in
Cure Parkinson's
5 years ago
Riveroxaban side effects
Since I’ve been on Riveroxaban I’ve had numbness in my feet and lower legs. Also pins and needles in my hands at night. My EP wants me to keep on it for the moment. Does anybody else suffer from these side effects?
Since I’ve been on Riveroxaban I’ve had numbness in my feet and lower legs. Also pins and needles in my hands at night. My EP wants me to keep on it for the moment. Does anybody else suffer from these side effects?
maria68
in
Anticoagulation Support
5 years ago
B12 Oral
Hi I am taking a multivitamin which has following composition. Vitamin B12 1500mcg + Vitamin B9 1.5mg + Vitamin B6 3mg + Vitamin D3 1000 IU + Alpha lipoic acid 100mg Can I take this daily for lifetime. I mean can I get vitamin toxicity if I pursue this for long term I have B12 deficiency and feel horrible
Hi I am taking a multivitamin which has following composition. Vitamin B12 1500mcg + Vitamin B9 1.5mg + Vitamin B6 3mg + Vitamin D3 1000 IU + Alpha lipoic acid 100mg Can I take this daily for lifetime. I mean can I get vitamin toxicity if I pursue this for long term I have B12 deficiency and feel horrible
Riseup01
in
Pernicious Anaemia Society
5 years ago
CBD with antidepressants and painkillers?
I am taking Venlalic XL 150 mg and Pregablin 150 mg for Fibromyalgia and am keen to understand the risks if any from also using CBD oil for the pain. Anyone have any info or experience, I would be grateful. The CBD oil is 2.75% recommended by a friend who does not take any antidepressants or painkillers
I am taking Venlalic XL 150 mg and Pregablin 150 mg for Fibromyalgia and am keen to understand the risks if any from also using CBD oil for the pain. Anyone have any info or experience, I would be grateful. The CBD oil is 2.75% recommended by a friend who does not take any antidepressants or painkillers
Monkey233
in
Pain Concern
5 years ago
Does exercise make your tingling/numbness worse?
When I walk or run, both of my feet and right leg up to mid-thigh tingle and feel “crawly” and occasionally my hands tingle, too. Within 5 minutes of stopping, it goes away. It’s not to where I can’t exercise, but it does feel strange the entire time. I’m on weekly b12 injections and the strange sensations
When I walk or run, both of my feet and right leg up to mid-thigh tingle and feel “crawly” and occasionally my hands tingle, too. Within 5 minutes of stopping, it goes away. It’s not to where I can’t exercise, but it does feel strange the entire time. I’m on weekly b12 injections and the strange sensations
Ashley820
in
Pernicious Anaemia Society
5 years ago
Preventing peripheral neuropathy during Taxotere treatment.
A question: I will be starting Taxotere soon. Has anyone used the cold gloves and footwear to avoid issues with peripheral neuropathy, and how successful were they in avoiding this side effect? Thanks in advance for your response.
A question: I will be starting Taxotere soon. Has anyone used the cold gloves and footwear to avoid issues with peripheral neuropathy, and how successful were they in avoiding this side effect? Thanks in advance for your response.
jholmq
in
Advanced Prostate Cancer
5 years ago
Recent bloods show elevated creatine. Systemic sclerosis and secondary Raynauds sufferer.
Hi all I suffer with Systemic sclerosis and secondary Raynauds with GI issues including dyspagia, GORD and Oesophagitis. I’ve recently had bloods taken and they found I have elevated creatine, could this be linked to the disease? Can the test be a one off elevation? Feeling concerned. Any information
Hi all I suffer with Systemic sclerosis and secondary Raynauds with GI issues including dyspagia, GORD and Oesophagitis. I’ve recently had bloods taken and they found I have elevated creatine, could this be linked to the disease? Can the test be a one off elevation? Feeling concerned. Any information
-missymoo
in
Scleroderma & Raynaud's UK (SRUK)
5 years ago
Muscle cramps
Does anyone get muscle cramps in their calf muscles and feet. I have a peripheral neuropathy from my b12 deficiency. The peripheral neuropathy is receding but still get muscle cramps. It has been 6 months since I started treatment. I started with injections and now I switched over to oral b12 1000. Feeling
Does anyone get muscle cramps in their calf muscles and feet. I have a peripheral neuropathy from my b12 deficiency. The peripheral neuropathy is receding but still get muscle cramps. It has been 6 months since I started treatment. I started with injections and now I switched over to oral b12 1000. Feeling
Coonass1
in
Pernicious Anaemia Society
5 years ago
Is creatine a bad idea?
Hi is it dodgy if I take creatine? I'm early stage one CLL. I've gone on a vegan low-carb diet and my numbers go down each month with it but I've lost some weight. I wonder if taking creatine to boost my muscles is a bad idea. Thank you!
Hi is it dodgy if I take creatine? I'm early stage one CLL. I've gone on a vegan low-carb diet and my numbers go down each month with it but I've lost some weight. I wonder if taking creatine to boost my muscles is a bad idea. Thank you!
Research123
in
CLL Support
5 years ago
Please help, my mother-in-law has ovarian cancer & is in denial.
My partner doesn't trust the doctors and is very much into
naturopathy
. He doesn't want her to go back for more chemotherapy or an operation, and his mum trusts him more than anyone and listens to him more than any Dr, so this is how they are going forward...
My partner doesn't trust the doctors and is very much into
naturopathy
. He doesn't want her to go back for more chemotherapy or an operation, and his mum trusts him more than anyone and listens to him more than any Dr, so this is how they are going forward...
Maria2828
in
My Ovacome
5 years ago
Right decision ?
Morning ladies from rainy Lincolnshire, I think I've decided not to have my last dose of taxol, ,will have carbo on its own, started back in March with three cycles of both ,the taxol nearly finished me ,excruciating leg and foot pain ,given morphine with little relief , last cycle took two weeks before
Morning ladies from rainy Lincolnshire, I think I've decided not to have my last dose of taxol, ,will have carbo on its own, started back in March with three cycles of both ,the taxol nearly finished me ,excruciating leg and foot pain ,given morphine with little relief , last cycle took two weeks before
fendweller
in
My Ovacome
5 years ago
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