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Which Estrogen Patch dose to use?
This plot shows the median serum estrogen (E2) concentration (in pg/mL) versus total Weekly Estrogen patch dose (mg/wk) from five different references ranging from 2000 to 2019. The data set from Smith et. al (2019) is for castrate-resistant prostate cancer men (CRPC), who are not taking ADT. Overall
This plot shows the median serum estrogen (E2) concentration (in pg/mL) versus total Weekly Estrogen patch dose (mg/wk) from five different references ranging from 2000 to 2019. The data set from Smith et. al (2019) is for castrate-resistant prostate cancer men (CRPC), who are not taking ADT. Overall
janebob99
in
Prostate Cancer Network
6 months ago
Advice on hormonal treatment?
hi all, 10 days post-lap here. Unfortunately ended up losing my left ovary and tube - had 4 endometriomas on it, 1 of which was 8cm, and this was all adhered to my rectum. So the surgeon said it needed to come out. I’m waiting for a post-op appointment but the consultant said the endo will likely come
hi all, 10 days post-lap here. Unfortunately ended up losing my left ovary and tube - had 4 endometriomas on it, 1 of which was 8cm, and this was all adhered to my rectum. So the surgeon said it needed to come out. I’m waiting for a post-op appointment but the consultant said the endo will likely come
Apprentice_Hag
in
Endometriosis UK
6 months ago
Newbie - Is this Normal? Should I have Treatment?
Good morning! I'm a newbie here and i'm just unsure as to whether I should accept what my GP is telling me and put up with it or go private. A bit of history - I'm 46, female, overall good health historically but diagnosed with Premature Ovarian Deficiency (Early menopause) in my early thirties.
Good morning! I'm a newbie here and i'm just unsure as to whether I should accept what my GP is telling me and put up with it or go private. A bit of history - I'm 46, female, overall good health historically but diagnosed with Premature Ovarian Deficiency (Early menopause) in my early thirties.
Ruthio77
in
Thyroid UK
6 months ago
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Question in Preparation for pBAT
For those who have experience with BAT: I’m getting ready to start my first 30 day cycle of pBAT this week. But I have a concern about my high SHBG (sex hormone binding globulin) level, which is 79 nmol/L. With Eligard ADT in the background, my pBAT program calls for 8 injections of T propionate
For those who have experience with BAT: I’m getting ready to start my first 30 day cycle of pBAT this week. But I have a concern about my high SHBG (sex hormone binding globulin) level, which is 79 nmol/L. With Eligard ADT in the background, my pBAT program calls for 8 injections of T propionate
Ichthus316
in
Fight Prostate Cancer
6 months ago
Similar question to Ezzedine. PSA rising
March 19 I was diagnosed with Gleason 9 prostate cancer. PSA was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my PSA was 0.01 (indecipherable) Then a year ago my PSA was 0.02, then 0.03 and last
March 19 I was diagnosed with Gleason 9 prostate cancer. PSA was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my PSA was 0.01 (indecipherable) Then a year ago my PSA was 0.02, then 0.03 and last
arry4424
in
Prostate Cancer Network
6 months ago
Very confused and don't know what to do to help my body heal
Hi everyone, I'm new to this forum and up to 6 weeks ago the only digestive concerns I had was Coeliac Disease and a sliding hiatal hernia which was discovered at my endoscopy 4 years ago. The hernia hasn't given me any bother up to this point except for the occasional bout of acid reflux every couple
Hi everyone, I'm new to this forum and up to 6 weeks ago the only digestive concerns I had was Coeliac Disease and a sliding hiatal hernia which was discovered at my endoscopy 4 years ago. The hernia hasn't given me any bother up to this point except for the occasional bout of acid reflux every couple
Sparkstar2
in
Acid Reflux Support
6 months ago
PROSTOX Tests
Is Conventionally Fractionated Radiotherapy (CFRT) mentioned on https://mirakind.org/prostox-testing/ the same as Intensity-Modulated Radiation Therapy (IMRT)? Specifically, does the CFRT test indicate if I am at high or low risk for IMRT? If the result of SBRT test indicates high risk, can I opt for
Is Conventionally Fractionated Radiotherapy (CFRT) mentioned on https://mirakind.org/prostox-testing/ the same as Intensity-Modulated Radiation Therapy (IMRT)? Specifically, does the CFRT test indicate if I am at high or low risk for IMRT? If the result of SBRT test indicates high risk, can I opt for
Infamous9597
in
Advanced Prostate Cancer
2 months ago
MRI report shows enhancing bone lesion is noted involving the left sphenoid bone.
That’s from an MRI taken six weeks after 10 sessions of IMRT were completed for a surgically inoperable metastasis in my skull. Apparently this means the contrast agent shows increased blood flow or activity in the tumor. Does that sound normal to still have increased blood flow or activity six weeks
That’s from an MRI taken six weeks after 10 sessions of IMRT were completed for a surgically inoperable metastasis in my skull. Apparently this means the contrast agent shows increased blood flow or activity in the tumor. Does that sound normal to still have increased blood flow or activity six weeks
Gl448
in
Advanced Prostate Cancer
2 months ago
RT with ADT Relogolix (Orgovyx) vs Enzalutamide (Xtandi) Side Effect Differences?
There may not be a lot of people that can offer anecdotal reports on both as monotherapies but the reason I ask is some studies in the last 3 years are showing administration of Xtandi during Radiotherapy has shown outcomes as good as if not better than RT + ADT. https://www.sciencedirect.com/science
There may not be a lot of people that can offer anecdotal reports on both as monotherapies but the reason I ask is some studies in the last 3 years are showing administration of Xtandi during Radiotherapy has shown outcomes as good as if not better than RT + ADT. https://www.sciencedirect.com/science
jazj
in
Advanced Prostate Cancer
6 months ago
hashimotos
hi, I’ve now been on Levothyroxine 25 since last June. None of my symptoms have changed. GP has just increased it to 50 and said to retest in 8 weeks. I have been asking for increase for quite a while as my level was still in the upper range of normal last test I had in October . My levels had been
hi, I’ve now been on Levothyroxine 25 since last June. None of my symptoms have changed. GP has just increased it to 50 and said to retest in 8 weeks. I have been asking for increase for quite a while as my level was still in the upper range of normal last test I had in October . My levels had been
Ozzy77
in
Thyroid UK
6 months ago
Is there such a thing as too fast of a recovery of T on iADT 🫨
After 2 years of ADT, I decided against continuing on that for life and to initiate iADT. Otherwise known as "taking a vacation".I am now 10 weeks without ADT, and my testosterone is already at 104. My questions this time are for others here who have had a similarly quick return of testosterone. I
After 2 years of ADT, I decided against continuing on that for life and to initiate iADT. Otherwise known as "taking a vacation".I am now 10 weeks without ADT, and my testosterone is already at 104. My questions this time are for others here who have had a similarly quick return of testosterone. I
Lewellen
in
Advanced Prostate Cancer
6 months ago
I don't know what to do anymore.
The last time I was here was about 9 months ago. For a reference here is a link to a thread I posted in before. https://healthunlocked.com/my-ocd/posts/149552410/my-ocd-is-sabotaging-my-attempts-to-treat-my-anxiety-and-depression.?responses=149622964 After I was hospitalized for 10 days, I lost my
The last time I was here was about 9 months ago. For a reference here is a link to a thread I posted in before. https://healthunlocked.com/my-ocd/posts/149552410/my-ocd-is-sabotaging-my-attempts-to-treat-my-anxiety-and-depression.?responses=149622964 After I was hospitalized for 10 days, I lost my
Metastar
in
My OCD Community
6 months ago
How many estrogen patches should I use?
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
janebob99
in
Advanced Prostate Cancer
6 months ago
How many estrogen patches to use?
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
janebob99
in
Prostate Cancer Network
6 months ago
European Society for Medical Oncology Congress - ESMO 2023 - Two Significant Lutetium Trials -mCRPC
Those following information coming from the ESMO Congress over the last few weeks will be aware of the many presentations focussed on the use of Lutetium. [i]
PSMAfore Study Unveils Game-Changing Results for Prostate Cancer Treatment
[/i] One such highlight was the results from the PSMAfore
Those following information coming from the ESMO Congress over the last few weeks will be aware of the many presentations focussed on the use of Lutetium. [i]
PSMAfore Study Unveils Game-Changing Results for Prostate Cancer Treatment
[/i] One such highlight was the results from the PSMAfore
marnieg46
in
Fight Prostate Cancer
10 months ago
Lupron SEs - legs
Appreciate this forum and all whom post. I’m amidst 2-year course of Lupron and experiencing persistent leg pain, worst in both Achilles tendons and calves. Recent salvage IMRT, too. Thoughts on managing such SEs appreciated. Cheers.
Appreciate this forum and all whom post. I’m amidst 2-year course of Lupron and experiencing persistent leg pain, worst in both Achilles tendons and calves. Recent salvage IMRT, too. Thoughts on managing such SEs appreciated. Cheers.
NickKnick
in
Advanced Prostate Cancer
2 months ago
Selenium Supplementation in Patients with Hashimoto Thyroiditis
I found this paper and thought I'll share. This is for patients with hashis, who are not yet on thyroid hormone replacement. https://pubmed.ncbi.nlm.nih.gov/38243784/
I found this paper and thought I'll share. This is for patients with hashis, who are not yet on thyroid hormone replacement. https://pubmed.ncbi.nlm.nih.gov/38243784/
buddy99
in
Thyroid UK
6 months ago
HRT FET - Day of transfer?
Hi everyone and thanks for the lovely support in this group - it’s been a comfort reading all the previous posts. I’m doing my first HRT FET, and just wondering around what day of the cycle people’s transfers were? My plan says to take oestrogen from day 1, then have a scan on day 8, and that’s it
Hi everyone and thanks for the lovely support in this group - it’s been a comfort reading all the previous posts. I’m doing my first HRT FET, and just wondering around what day of the cycle people’s transfers were? My plan says to take oestrogen from day 1, then have a scan on day 8, and that’s it
Learningdaybyday
in
Fertility Network UK
6 months ago
How prostate cancer transforms into aggressive NEPC following treatment with anti-androgen therapy.
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
Scout4answers
in
Advanced Prostate Cancer
10 months ago
What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
103532
in
Advanced Prostate Cancer
4 months ago
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