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Autoimmune neurological B12 deficiency
I came across this fascinating study on an autoimmune condition that results in B12 deficiency selectively in the central nervous system. Cerebrospinal fluid B12 is essentially non-existent but serum levels are normal, making this very hard to detect! https://www.medrxiv.org/content/10.1101/2023.08.21.23294253v1
I came across this fascinating study on an autoimmune condition that results in B12 deficiency selectively in the central nervous system. Cerebrospinal fluid B12 is essentially non-existent but serum levels are normal, making this very hard to detect! https://www.medrxiv.org/content/10.1101/2023.08.21.23294253v1
etreas
in
Pernicious Anaemia Society
2 months ago
Just received my blood test results
TSH 4.6 mIU/L (0.27 - 4.2) FT3 3.7 pmol/L (3.1 - 6.8) FT4 14.1 pmol/L (12 - 22) THYROGLOBULIN ANTIBODIES 16.3 kIU/L (0 - 115) THYROID PEROXIDASE ANTIBODIES 10.1 kIU/L (0 - 34 ) FOLATE 9.3 nmol/L ( > 7) VITAMIN B12 - ACTIVE >150 pmol/L (
TSH 4.6 mIU/L (0.27 - 4.2) FT3 3.7 pmol/L (3.1 - 6.8) FT4 14.1 pmol/L (12 - 22) THYROGLOBULIN ANTIBODIES 16.3 kIU/L (0 - 115) THYROID PEROXIDASE ANTIBODIES 10.1 kIU/L (0 - 34 ) FOLATE 9.3 nmol/L ( > 7) VITAMIN B12 - ACTIVE >150 pmol/L (
diamondgirl902
in
Thyroid UK
2 months ago
Health anxiety... bloating, diarrhea, etc.
I have aalways sufferred from digestive problems, constipation, bloating, etc... and also I was diagnosed 15 years ago with general anxiety disorder. Recently, two weeks ago, I started with diarrhea and bloating, I just thought it to be another of the many indigestions I get, but it's been two weeks
I have aalways sufferred from digestive problems, constipation, bloating, etc... and also I was diagnosed 15 years ago with general anxiety disorder. Recently, two weeks ago, I started with diarrhea and bloating, I just thought it to be another of the many indigestions I get, but it's been two weeks
munrapz
in
Anxiety Support
2 months ago
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Bloating, diarrhea, and general body ache.
I have aalways sufferred from digestive problems, constipation, bloating, etc... and also I was diagnosed 15 years ago with general anxiety disorder. Recently, two weeks ago, I started with diarrhea and bloating, I just thought it to be another of the many indigestions I get, but it's been two weeks
I have aalways sufferred from digestive problems, constipation, bloating, etc... and also I was diagnosed 15 years ago with general anxiety disorder. Recently, two weeks ago, I started with diarrhea and bloating, I just thought it to be another of the many indigestions I get, but it's been two weeks
munrapz
in
IBS Network
2 months ago
pelvic varices
hi. I’m a 62 year old of 5 children. After 7 months of trying to find the reason for my sudden pain and bloating I was told I had large volume pelvic varices which showed on both MRI and CT scan which I had done privately as NHS were done with me after 2 ultrasounds and CA125 tests came back clear. I
hi. I’m a 62 year old of 5 children. After 7 months of trying to find the reason for my sudden pain and bloating I was told I had large volume pelvic varices which showed on both MRI and CT scan which I had done privately as NHS were done with me after 2 ultrasounds and CA125 tests came back clear. I
MillieEllie
in
Pelvic Pain Support Network
2 months ago
Bad ct scan
Good morning Ladies, Does anyone have any information on pleural fluid in the lung? I’m currently on first line of RX for MBC in lung with faslodex. Scans are showing small pleural fluid and nodules, etc. I’m so scared! Any thoughts? Thanks, Susie
Good morning Ladies, Does anyone have any information on pleural fluid in the lung? I’m currently on first line of RX for MBC in lung with faslodex. Scans are showing small pleural fluid and nodules, etc. I’m so scared! Any thoughts? Thanks, Susie
Likes
in
SHARE Metastatic Breast Cancer
6 months ago
Salad - Good apparantly
I have IBS for years and its been behaving recently and an IBD. I have noticed in the last 6 months or more I am bloated from a basic salad, containing tomatoes, cucumber, peppers and lettace or spinach with chicken or chickpeas (home cooked). Has anyone else had any irritation from salad before?
I have IBS for years and its been behaving recently and an IBD. I have noticed in the last 6 months or more I am bloated from a basic salad, containing tomatoes, cucumber, peppers and lettace or spinach with chicken or chickpeas (home cooked). Has anyone else had any irritation from salad before?
AGB111
in
IBS Network
2 months ago
Shocking story about women dying of CRF/ME
Did anyone read about the women who died from CFS/ME? https://news.sky.com/story/woman-with-me-died-after-begging-gp-for-help-inquest-told-13183530 Why didn't anyone try B12 and see if it could help her? If you look online there is masses of information about how B12 can help CFS/ME. For example
Did anyone read about the women who died from CFS/ME? https://news.sky.com/story/woman-with-me-died-after-begging-gp-for-help-inquest-told-13183530 Why didn't anyone try B12 and see if it could help her? If you look online there is masses of information about how B12 can help CFS/ME. For example
charks
in
Pernicious Anaemia Society
2 months ago
Gastritis and B12 deficiency
Good morning all you lovely people. Does anybody have gastritis as their root cause of B12D? I was hospitalised in 2009 with gastritis and I now believe that this was the beginning of my problems, with a Naproxen prescription and high stress levels in 2023 really exacerbating things in my stomach to
Good morning all you lovely people. Does anybody have gastritis as their root cause of B12D? I was hospitalised in 2009 with gastritis and I now believe that this was the beginning of my problems, with a Naproxen prescription and high stress levels in 2023 really exacerbating things in my stomach to
ClaireWF1346
in
Pernicious Anaemia Society
2 months ago
In vivo and on breast cancer bone metastasis but....100% with repurposed drugs
Ok they are not saying which drugs and I can quite understand them, but results seem very promising: https://medicalxpress.com/news/2024-04-drugs-hinder-bone-metastasis-breast.html "Based on their findings, the researchers predict that in the future, the treatment can be applied to human patients with
Ok they are not saying which drugs and I can quite understand them, but results seem very promising: https://medicalxpress.com/news/2024-04-drugs-hinder-bone-metastasis-breast.html "Based on their findings, the researchers predict that in the future, the treatment can be applied to human patients with
Maxone73
in
Fight Prostate Cancer
6 months ago
I’m still here :)
it’s been a while and my last post was not very positive . This is a quick update . I’m still unclear as to how I got here with my illness but I received palliative chemotherapy six cylcles one every three weeks. I think it was a variation of chop plus an immunotherapy drug beginning with B . The treatment
it’s been a while and my last post was not very positive . This is a quick update . I’m still unclear as to how I got here with my illness but I received palliative chemotherapy six cylcles one every three weeks. I think it was a variation of chop plus an immunotherapy drug beginning with B . The treatment
Hilo13
in
CLL Support
23 days ago
These are my Iron levels - have RLS but also Parkinson's
My original post was https://healthunlocked.com/rlsuk/posts/150970580/low-iron-rls-but-also-with-parkinsons If you remember I had had a test for iron done on 30th May (ferritin only) which came back as Serum ferritin level 15 ng/mL [10.0 - 180.0] So I requested and got another test for Iron, (this
My original post was https://healthunlocked.com/rlsuk/posts/150970580/low-iron-rls-but-also-with-parkinsons If you remember I had had a test for iron done on 30th May (ferritin only) which came back as Serum ferritin level 15 ng/mL [10.0 - 180.0] So I requested and got another test for Iron, (this
Jess123dog
in
Restless Legs Syndrome
2 months ago
ppi advice please
hi today I had to have a gastroscopy /endoscopy as they suspected ulcers due to all the ibuprofen and naproxen post hip surgery - they have prescribed me esomaprazole as they’ve found 2 peptic ulcers I remember reading proton pump inhibitors could make the RLS worse Any help please as I did discuss with
hi today I had to have a gastroscopy /endoscopy as they suspected ulcers due to all the ibuprofen and naproxen post hip surgery - they have prescribed me esomaprazole as they’ve found 2 peptic ulcers I remember reading proton pump inhibitors could make the RLS worse Any help please as I did discuss with
Zenawarrior73
in
Restless Legs Syndrome
2 months ago
B12 how much and how often
I’ve been struggling with PA for 2 and 1/2 years. No one would listen. Finally from Israel I was advised to get the Intrinsic Factor Antibody Blood Test and the Parietal Cell Antibody Blood Test. Pernicious Anemia. I have to take a shot of Methylcobalamin daily. The Israelis recommend taking a shot
I’ve been struggling with PA for 2 and 1/2 years. No one would listen. Finally from Israel I was advised to get the Intrinsic Factor Antibody Blood Test and the Parietal Cell Antibody Blood Test. Pernicious Anemia. I have to take a shot of Methylcobalamin daily. The Israelis recommend taking a shot
Jeep13
in
Pernicious Anaemia Society
2 months ago
ACTOv clinical trial
HiWonder if anyone is taking part in the ACTOv, trial for patients with high-grade serous and endometrioid ovarian cancer. My wife is facing a reoccurrence and further carboplatin treatment
HiWonder if anyone is taking part in the ACTOv, trial for patients with high-grade serous and endometrioid ovarian cancer. My wife is facing a reoccurrence and further carboplatin treatment
Cardiff05
in
My Ovacome
6 months ago
Does anyone have a weak heart and fast heartbeat, physical anxiety feeling, as their main low b12 symptom?
I sometimes get a feeling of weak heart and uncomfortable chest, too fast heartbeat, and a feeling like physical anxiety in my stomach/heart while mentally feeling completely calm so it's definitely a physically caused thing. My heart area feels uncomfortable and it makes sleep very difficult. I also
I sometimes get a feeling of weak heart and uncomfortable chest, too fast heartbeat, and a feeling like physical anxiety in my stomach/heart while mentally feeling completely calm so it's definitely a physically caused thing. My heart area feels uncomfortable and it makes sleep very difficult. I also
Carrie234
in
Pernicious Anaemia Society
2 months ago
Vomiting in night ?Take more pred today
hallo I was vomiting for about 5 hours in the night, roughly once an hour. I think it was food poisoning. I started about two /two and a half hours after taking my preds, which I take in an enteric coated capsule. I take a split dose and this morning I took the morning dose, much later than usual, as
hallo I was vomiting for about 5 hours in the night, roughly once an hour. I think it was food poisoning. I started about two /two and a half hours after taking my preds, which I take in an enteric coated capsule. I take a split dose and this morning I took the morning dose, much later than usual, as
Freshairfiend
in
PMRGCAuk
2 months ago
Low Fibre Diet
Hello I’ve not posted on here for some time. A few month ago I was diagnosed with Cancer. I am undergoing radiotherapy and low dose of chemo. I have been asked to reduce my fibre intake as much as I can. This goes well against the grain but naturally I want to do what ever helps. It means next to no
Hello I’ve not posted on here for some time. A few month ago I was diagnosed with Cancer. I am undergoing radiotherapy and low dose of chemo. I have been asked to reduce my fibre intake as much as I can. This goes well against the grain but naturally I want to do what ever helps. It means next to no
Reving
in
Healthy Eating
2 months ago
Ct scan
I have ibs and bile acid malabsorption I have had stomach problems for years colprotin is on 113 I had a ct scan done over a week doctors rang yesterday with results came back as thickening of stomach linning now doctors have done urgent referal to gastroenterologist and probably will have to have endoscopy
I have ibs and bile acid malabsorption I have had stomach problems for years colprotin is on 113 I had a ct scan done over a week doctors rang yesterday with results came back as thickening of stomach linning now doctors have done urgent referal to gastroenterologist and probably will have to have endoscopy
Netbet22
in
IBS Network
2 months ago
b12 and “liver storage”
Every time I think I have a handle on how this essential vitamin works, I read something and have to adjust my understanding. Has anyone read this? Enough to have a discussion about it? [u]
The Enterohepatic Circulation of Vitamin B12
[/u] My takeaway quotes were: “[i]The reabsorption of
Every time I think I have a handle on how this essential vitamin works, I read something and have to adjust my understanding. Has anyone read this? Enough to have a discussion about it? [u]
The Enterohepatic Circulation of Vitamin B12
[/u] My takeaway quotes were: “[i]The reabsorption of
PlatypusProfit8077
in
Pernicious Anaemia Society
2 months ago
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