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Hope for the future
New research into autoimmune liver condition suggests unique cell movements may be driving disease A Birmingham study reveals a novel cellular phenomenon could be responsible for the onset of primary biliary cholangitis (PBC). Research suggests that a recent understanding of cell movements may
New research into autoimmune liver condition suggests unique cell movements may be driving disease A Birmingham study reveals a novel cellular phenomenon could be responsible for the onset of primary biliary cholangitis (PBC). Research suggests that a recent understanding of cell movements may
DonnaBoll
Administrator
in
PBC Foundation
6 months ago
Wednesday Words
The words this week I want to define are
alkaline phosphatase.
Alkaline phosphatase (ALP)
is an enzyme that is released by the bile ducts cells ( among other organs). The release of ALP is a marker of stress or injury. So the more injury or stress to the bile duct cells, the higher
The words this week I want to define are
alkaline phosphatase.
Alkaline phosphatase (ALP)
is an enzyme that is released by the bile ducts cells ( among other organs). The release of ALP is a marker of stress or injury. So the more injury or stress to the bile duct cells, the higher
DonnaBoll
Administrator
in
PBC Foundation
6 months ago
Severe coronary atherosclerosis and ADT
My recent PET / CT scan mentions severe coronary atherosclerosis. Previous one only said The heart is normal in size with scattered coronary artery calcifications. Also the new PET ? CT said something about heart enlargement but the last one said size normal. Previous scans also said there was an enlarged
My recent PET / CT scan mentions severe coronary atherosclerosis. Previous one only said The heart is normal in size with scattered coronary artery calcifications. Also the new PET ? CT said something about heart enlargement but the last one said size normal. Previous scans also said there was an enlarged
spencoid2
in
Advanced Prostate Cancer
10 months ago
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A new kid on the block? Nemtabrutinib
Hi All, There is a new targeted drug in Clinical Trials that may offer a new treatment option for us CLLers—Nemtabrutinib. For the entire article on this drug go to cancer.osu.edu and scroll down to “First in human trial of new drug raises hopes for patients with relapsed blood cancer” dated 11/06/
Hi All, There is a new targeted drug in Clinical Trials that may offer a new treatment option for us CLLers—Nemtabrutinib. For the entire article on this drug go to cancer.osu.edu and scroll down to “First in human trial of new drug raises hopes for patients with relapsed blood cancer” dated 11/06/
Varney
in
CLL Support
10 months ago
New member - Post ET MF (Australia)
I'm 42, married with six children, and I live in Australia. In 2013, I was diagnosed with CAL-R positive ET. I started taking aspirin and managed pretty well. After a spontaneous bleed in my right quadricep, it was discovered that I also had a genetic bleeding disorder, dysfibrinogenemia. After that
I'm 42, married with six children, and I live in Australia. In 2013, I was diagnosed with CAL-R positive ET. I started taking aspirin and managed pretty well. After a spontaneous bleed in my right quadricep, it was discovered that I also had a genetic bleeding disorder, dysfibrinogenemia. After that
Hatchie
in
MPN Voice
4 months ago
colonoscopy and ct scan
recently had colonoscopy and then 3 weeks later Ct scan on colon. Both of these procedures I had to take bowel prep. So with in 3 weeks 2 lots of bowel prep. Now, nearly 3 weeks on I keep getting stomach pains and feeling nauseous. Anyone else had this?
recently had colonoscopy and then 3 weeks later Ct scan on colon. Both of these procedures I had to take bowel prep. So with in 3 weeks 2 lots of bowel prep. Now, nearly 3 weeks on I keep getting stomach pains and feeling nauseous. Anyone else had this?
jsee
in
IBS Network
9 months ago
Iron supplement recommendations please
Can anyone recommend an iron supplement that won't cause constipation? My iron is low so GP prescribed me 200mg Ferrus Sulphate. I'm supposed to be taking 3 a day but I can barely manage 1, my bowels do not agree at all! 🙈 I was looking at Floradix liquid iron however it contains b vitamins which I'm
Can anyone recommend an iron supplement that won't cause constipation? My iron is low so GP prescribed me 200mg Ferrus Sulphate. I'm supposed to be taking 3 a day but I can barely manage 1, my bowels do not agree at all! 🙈 I was looking at Floradix liquid iron however it contains b vitamins which I'm
Mummybear0213
in
Thyroid UK
8 months ago
Have you had chemo via cannula?
Hello Ladies, After a summer of multiple surgeries and the diagnosis of rare aggressive mucinous ovarian cancer, I had the good news that the cancer hasn’t spread to my lymph nodes which makes it 1C. While my oncologist explained that it’s difficult to quantify the benefits of adjuvant chemo due to
Hello Ladies, After a summer of multiple surgeries and the diagnosis of rare aggressive mucinous ovarian cancer, I had the good news that the cancer hasn’t spread to my lymph nodes which makes it 1C. While my oncologist explained that it’s difficult to quantify the benefits of adjuvant chemo due to
OCacc
in
My Ovacome
10 months ago
Stem cell transplant (SCT) 15 months on
I'm now 15 months after my SCT and in my my recent review my figures are improving:WBC 4.0 HB 139 Neut 2.3, lymph1.12 and platelets 106 ( highest for a couple of years). I also had my CD4 lymphocytes measured and can now come off Acyclovir and pentamidine. Hooray! I hated those nebulisers. This leaves
I'm now 15 months after my SCT and in my my recent review my figures are improving:WBC 4.0 HB 139 Neut 2.3, lymph1.12 and platelets 106 ( highest for a couple of years). I also had my CD4 lymphocytes measured and can now come off Acyclovir and pentamidine. Hooray! I hated those nebulisers. This leaves
Scaredy_cat
in
MPN Voice
4 months ago
enlarged lymp node
I had a ct scan yesterday and got the results today. I have enlarged left axillary lymph nodes, largest measuring 19x14 mm, previously subcentimeter and measured 10x8.5. Enlarged left subpectoral lymph nodes are identified. Nothing on the right side. I had a covid vacine about 2-3 weeks ago. The
I had a ct scan yesterday and got the results today. I have enlarged left axillary lymph nodes, largest measuring 19x14 mm, previously subcentimeter and measured 10x8.5. Enlarged left subpectoral lymph nodes are identified. Nothing on the right side. I had a covid vacine about 2-3 weeks ago. The
DianeSH
in
CLL Support
10 months ago
Study reveals genetic chain reaction that drives the spread of prostate cancer
[i]Science keeps getting closer to stopping the spread of cancer.[/i] [i]Scout[/i] From the Male Care Prostrate news letter [i][/i] NOVEMBER 6, 2023 New research from scientists at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) determined that a particular
[i]Science keeps getting closer to stopping the spread of cancer.[/i] [i]Scout[/i] From the Male Care Prostrate news letter [i][/i] NOVEMBER 6, 2023 New research from scientists at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) determined that a particular
Scout4answers
in
Advanced Prostate Cancer
10 months ago
Trametinib!
Have been diagnosed with 3c stage low grade ovarian cancer back in 2016, after debunking and several rounds of chemotherapy remission for 7 years, now the big C is back again, I have been offered the new drug Trametinib which I need to start soon, reading on the all side effects gives me a real scare
Have been diagnosed with 3c stage low grade ovarian cancer back in 2016, after debunking and several rounds of chemotherapy remission for 7 years, now the big C is back again, I have been offered the new drug Trametinib which I need to start soon, reading on the all side effects gives me a real scare
Izoominka
in
My Ovacome
10 months ago
stem cell transplant survival with MF
This link gives some figures for overall survival with or without a transplant. The headline really is the initial mortality close to the transplant is only worth risking if your MF is quite bad. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218417/
This link gives some figures for overall survival with or without a transplant. The headline really is the initial mortality close to the transplant is only worth risking if your MF is quite bad. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218417/
Scaredy_cat
in
MPN Voice
4 months ago
pregabalin and iron
Hello, I have tried googling if there is any interaction between pregabalin and iron but can’t find anything. I take an iron tablet due to low iron (morning and it has not helped) but will switch to iron bisglycinate at night after reading posts here. I stop eating at 6:30pm so I can take my pregabalin
Hello, I have tried googling if there is any interaction between pregabalin and iron but can’t find anything. I take an iron tablet due to low iron (morning and it has not helped) but will switch to iron bisglycinate at night after reading posts here. I stop eating at 6:30pm so I can take my pregabalin
e365
in
Restless Legs Syndrome
8 months ago
Where do I go from here?
I've struggled with anxiety and panic attacks and depression since I was 4 years old. I thought I was doing better and then this week I started having unprovoked panic attacks again. I lost my ability to speak for 24 hours. It was terrifying. Should I look into IOP or PHP? Is outpatient just not enough
I've struggled with anxiety and panic attacks and depression since I was 4 years old. I thought I was doing better and then this week I started having unprovoked panic attacks again. I lost my ability to speak for 24 hours. It was terrifying. Should I look into IOP or PHP? Is outpatient just not enough
ChaoticEmu
in
Anxiety and Depression Support
6 months ago
PSA Rising Dx 06/2022 PSA 864.42 to 01/2023 <0.06 now no longer undetectable, I won’t see DR until next month, What will the Dr do?
Diagnosed 07/01/2022 PSA 942.40 Gleason 8 ductal without large cribform gland / Gleason 9 4+5 after Davinci RP w/ LNR cT3b CN0 cM1b Gleason 8/9 Stage 4 Grade 5 : 4+5=9 Low Volume High Grade ypT3a YPT3a 3 lytic lesions resolved to 1 mild avid lesion Biopsy 15 samples 4 adenocarcinoma
Diagnosed 07/01/2022 PSA 942.40 Gleason 8 ductal without large cribform gland / Gleason 9 4+5 after Davinci RP w/ LNR cT3b CN0 cM1b Gleason 8/9 Stage 4 Grade 5 : 4+5=9 Low Volume High Grade ypT3a YPT3a 3 lytic lesions resolved to 1 mild avid lesion Biopsy 15 samples 4 adenocarcinoma
Shorehousejam
in
Advanced Prostate Cancer
10 months ago
set back
my mind is going in overdrive with worry and anxiety. I’ve told someone about a couple of my anxiety triggers that I’ve never told anyone before. The thing is they’re so pathetic and small that I feel so ashamed and embarrassed and wished I’d never let the cat out of the bag so to speak. I was under
my mind is going in overdrive with worry and anxiety. I’ve told someone about a couple of my anxiety triggers that I’ve never told anyone before. The thing is they’re so pathetic and small that I feel so ashamed and embarrassed and wished I’d never let the cat out of the bag so to speak. I was under
Junkjournal1
in
Anxiety and Depression Support
6 months ago
stomach Cancer
hi everyone, I suffer with stomach issues. The usual gastritis/oesophagitis. Long story short. Looking for guidance really. My Mum had stomach cancer and then got another primary in her Oesophagus at the same time. Sadly gone. But I am getting full easy when I eat, pain in stomach, bringing food back
hi everyone, I suffer with stomach issues. The usual gastritis/oesophagitis. Long story short. Looking for guidance really. My Mum had stomach cancer and then got another primary in her Oesophagus at the same time. Sadly gone. But I am getting full easy when I eat, pain in stomach, bringing food back
Crinkles2020
in
Oesophageal & Gastric Cancer
8 months ago
End of IBrance …
After 6 months of consistently rising tumor markers and increasing back and leg pain, a recent flurry of scans and an MRI have finally brought us to the realization that the IBrance and Anastrozole combo is failing to control the bone Mets in my pelvis, sacrum and L5. I’m in the process of starting
After 6 months of consistently rising tumor markers and increasing back and leg pain, a recent flurry of scans and an MRI have finally brought us to the realization that the IBrance and Anastrozole combo is failing to control the bone Mets in my pelvis, sacrum and L5. I’m in the process of starting
Dragonfly2
in
SHARE Metastatic Breast Cancer
10 months ago
Vitamin/mineral deficiencies
Hi. I've had Pbc for 6 yrs now. Recently I've noticed that I am more fatigued than normal. I asked for my blood results over the last 10 yrs . I noticed a progressive decline in my ferritin levels over the last few yes. I had a vitamin b12 level done recently and it was just above the borderline/normal
Hi. I've had Pbc for 6 yrs now. Recently I've noticed that I am more fatigued than normal. I asked for my blood results over the last 10 yrs . I noticed a progressive decline in my ferritin levels over the last few yes. I had a vitamin b12 level done recently and it was just above the borderline/normal
Finn2021
in
PBC Foundation
8 months ago
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