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Horizant Cost for Those In US
HI, All. Forgive me if this already was covered elsewhere. Briefly, I was prescribed Horizant. At the time of the Rx, the "sleep expert" neurologist noted that it was very expensive and likely not covered by health insurance. The cost of a 30 day supply at my local pharmacy was $450, none of which
HI, All. Forgive me if this already was covered elsewhere. Briefly, I was prescribed Horizant. At the time of the Rx, the "sleep expert" neurologist noted that it was very expensive and likely not covered by health insurance. The cost of a 30 day supply at my local pharmacy was $450, none of which
Hidden
in
Restless Legs Syndrome
2 years ago
Berberine & gut microbes that increase L-Dopa (contains good explanation of sequence leading to dopamine production)
“ They started testing the effects of berberine and l-dopa/dopamine-producing gut bacteria in a mouse model of Parkinson’s. They discovered that treating animals with berberine, or transplanting E. faecalis and E. faecium into their gastrointestinal tract could improve both their behavior and brain function
“ They started testing the effects of berberine and l-dopa/dopamine-producing gut bacteria in a mouse model of Parkinson’s. They discovered that treating animals with berberine, or transplanting E. faecalis and E. faecium into their gastrointestinal tract could improve both their behavior and brain function
Little_apple
in
Cure Parkinson's
2 years ago
Quitting Ropinirole ... Weeks 3 to 5
Hi all, It's now been 5 weeks since my last ropinirole. I'll quickly summarise my experience here and I have a couple of questions for those of you more experienced than I (questions at bottom) Week 1 and 2 can be found here Week 3 - RLS symptoms stayed the same but now have started experiencing waves
Hi all, It's now been 5 weeks since my last ropinirole. I'll quickly summarise my experience here and I have a couple of questions for those of you more experienced than I (questions at bottom) Week 1 and 2 can be found here Week 3 - RLS symptoms stayed the same but now have started experiencing waves
Hazuki
in
Restless Legs Syndrome
2 years ago
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Pramipexole vacations
I am currently completely off Pramipexole for 7 months, after being on it for 6 years. It was the only medication that gave me excellent relief and no side effects, except one sudden episode of augmentation . All the augmentation symptoms have resolved, but the symptoms of course are daily and last
I am currently completely off Pramipexole for 7 months, after being on it for 6 years. It was the only medication that gave me excellent relief and no side effects, except one sudden episode of augmentation . All the augmentation symptoms have resolved, but the symptoms of course are daily and last
Hidden
in
Restless Legs Syndrome
2 years ago
Decreasing dopamine treatment levels In late stage Parkinson’s disease.
I am questioning the neurological position that decreasing dopamine treatments is a proper method for a patient exhibiting a deteriorating clinical picture.
I am questioning the neurological position that decreasing dopamine treatments is a proper method for a patient exhibiting a deteriorating clinical picture.
BoBo9-Breeze
in
Cure Parkinson's
2 years ago
pramipexole (containing Dopamine), can it contribute to heart regurgitation?
I recently had an echocardiogram after chest x-ray for breathlessness and it was thought to show an enlarged heart , but later found it wasn’t, hence the ecg. It has shown that I have some regurgitation which GP said nothing to worry about but I have read that Dopamine can be a cause of this. Can anyone
I recently had an echocardiogram after chest x-ray for breathlessness and it was thought to show an enlarged heart , but later found it wasn’t, hence the ecg. It has shown that I have some regurgitation which GP said nothing to worry about but I have read that Dopamine can be a cause of this. Can anyone
Sunny70
in
Restless Legs Syndrome
2 years ago
I'm new here. Turning 42 years old next year. Just want to get a better life for my 2 kids. Have ADHD.
Currently living in Utah. Just recently got diagnosed with ADHD and medicated for it. The doctor gave me 10mg of the generic Adderall and it's the short-term release one. It's just once a day too. I do not feel anything different. Feel less anxious. Not only do I have ADHD but also have a mild case of
Currently living in Utah. Just recently got diagnosed with ADHD and medicated for it. The doctor gave me 10mg of the generic Adderall and it's the short-term release one. It's just once a day too. I do not feel anything different. Feel less anxious. Not only do I have ADHD but also have a mild case of
Hulk323
in
CHADD's Adult ADHD Support
2 years ago
Castor Oil Packs - for elimination , to reduce inflammation and parasympathetic state
https://terrywahls.com/castoroilpacks/ https://youtu.be/movxi8Ar238 The doctor explains, “Your body is working against you, attacking its own cells. For some reason, which we don’t know,” (I have a pretty good idea why – hang tight we will talk about it here) “your body has decided to attack itself
https://terrywahls.com/castoroilpacks/ https://youtu.be/movxi8Ar238 The doctor explains, “Your body is working against you, attacking its own cells. For some reason, which we don’t know,” (I have a pretty good idea why – hang tight we will talk about it here) “your body has decided to attack itself
Little_apple
in
Cure Parkinson's
2 years ago
My Opinion: Collateral Damage due to Discontinuance of Pramipexole
Hi, All. I was going to write about this year's months-long Hell due to discontinuance of pramipexole virtually cold-turkey, following more than two decades of daily use. Having found that circumstance recently has been described by others, I think it may be more helpful if I instead comment on the
Hi, All. I was going to write about this year's months-long Hell due to discontinuance of pramipexole virtually cold-turkey, following more than two decades of daily use. Having found that circumstance recently has been described by others, I think it may be more helpful if I instead comment on the
Hidden
in
Restless Legs Syndrome
2 years ago
T3 only tiered after breakfast lack of motivation
I was taking 3 years t3 only with 3x 25mg a day. I was doing well. After 2,5 years I got extreme tierdness after eating my first meal (breakfast) doesn't matter if 1-5 hours after getting up. I had to nap. Like a crash. Next meal was no problem with tierdness. When this occur i got after 1 month total
I was taking 3 years t3 only with 3x 25mg a day. I was doing well. After 2,5 years I got extreme tierdness after eating my first meal (breakfast) doesn't matter if 1-5 hours after getting up. I had to nap. Like a crash. Next meal was no problem with tierdness. When this occur i got after 1 month total
charley123
in
Thyroid UK
2 years ago
An exciting new clinical trial called STEM-PD is due to start in Sweden and the UK for Parkinson’s.
The symptoms of Parkinson’s are caused by the loss of dopamine-producing nerve cells or neurons in the brain; and researchers have long proposed using cell transplantation as a treatment option for replacing these lost dopamine cells. One challenge presented to research teams however has been generating
The symptoms of Parkinson’s are caused by the loss of dopamine-producing nerve cells or neurons in the brain; and researchers have long proposed using cell transplantation as a treatment option for replacing these lost dopamine cells. One challenge presented to research teams however has been generating
Farooqji
in
Cure Parkinson's
2 years ago
Dihexa peptide shows potential for PD and ALZ and (I believe) is currently available
hypothesis, demonstrating that Dihexa, given by abdominal injection or orally, completely restored lost motor function. Moreover, staining for tyrosine hydroxylase (TH), a marker for the dopamine neurons that were lost following chemical lesioning, returned to near normal after 34 days of treatment.
hypothesis, demonstrating that Dihexa, given by abdominal injection or orally, completely restored lost motor function. Moreover, staining for tyrosine hydroxylase (TH), a marker for the dopamine neurons that were lost following chemical lesioning, returned to near normal after 34 days of treatment.
Little_apple
in
Cure Parkinson's
2 years ago
Irisin reduces AS aggregation
Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin Irisin is an exercise-induced polypeptide secreted by skeletal muscle that crosses the blood–brain barrier and mediates certain effects of exercise. Here, we show that irisin prevents pathologic α-synuclein (α-syn)-induced
Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin Irisin is an exercise-induced polypeptide secreted by skeletal muscle that crosses the blood–brain barrier and mediates certain effects of exercise. Here, we show that irisin prevents pathologic α-synuclein (α-syn)-induced
Little_apple
in
Cure Parkinson's
2 years ago
Trialling Buprenorphine and Dipyramidole - experience
Hello everyone! I’ve been around for a little while but I’ve been waiting for something definite to report. At age 56, the RLS was getting very disruptive so I had to find an alternative to my usual sleep medication. It took me a few years. In the end I returned to my old GP, who listened and thought
Hello everyone! I’ve been around for a little while but I’ve been waiting for something definite to report. At age 56, the RLS was getting very disruptive so I had to find an alternative to my usual sleep medication. It took me a few years. In the end I returned to my old GP, who listened and thought
Typicallygaslit
in
Restless Legs Syndrome
2 years ago
Interesting Information in an Article in the Washington Post
Parkinson’s patients and researchers search for exercise ‘prescription’ A mix of high-intensity aerobics and balance, strengthening and stretching exercises may delay the disease’s onset or, ideally, prevent it altogether. By Marlene Cimons Washington Post November 26, 2022 at 7:05 a.m. EST Retired
Parkinson’s patients and researchers search for exercise ‘prescription’ A mix of high-intensity aerobics and balance, strengthening and stretching exercises may delay the disease’s onset or, ideally, prevent it altogether. By Marlene Cimons Washington Post November 26, 2022 at 7:05 a.m. EST Retired
SueJohnson
in
Cure Parkinson's
2 years ago
Opicrapone
Hello. My (new) neurologist has suggested Opicrapone, which he says prevents spme protein from interferring with the usage of Dopamine, and therefore I should be able to decrease my Sinemet dosages. Has anyone else tried this, and if so, what was the outcome? Were you able to decrease the C/L, and
Hello. My (new) neurologist has suggested Opicrapone, which he says prevents spme protein from interferring with the usage of Dopamine, and therefore I should be able to decrease my Sinemet dosages. Has anyone else tried this, and if so, what was the outcome? Were you able to decrease the C/L, and
willowone123
in
Cure Parkinson's
2 years ago
antidepressants that don’t cause tinnitus
been on sertraline that caused T most likely with phenegan last year On zopiclone for sleep and no antidepressants Trazedone mirtazapine St John’s wort saffron 5 htp all cause tinnitus with me Any other suggestions? It will have to be one that doesn’t put serotonin levels up & targets dopamine on
been on sertraline that caused T most likely with phenegan last year On zopiclone for sleep and no antidepressants Trazedone mirtazapine St John’s wort saffron 5 htp all cause tinnitus with me Any other suggestions? It will have to be one that doesn’t put serotonin levels up & targets dopamine on
Meldge
in
Tinnitus UK
2 years ago
Is Jornay PM a better option for someone with a tendency to abuse adderall?
Adderall is great when I take my prescribed 30mg dose, but occasionally I double or triple my dose in attempts to combat depression symptoms. Sometimes I’ll take more later to put off the crash, and then I don’t sleep and function so poorly for the next couple of days that I might as well be unmedicated
Adderall is great when I take my prescribed 30mg dose, but occasionally I double or triple my dose in attempts to combat depression symptoms. Sometimes I’ll take more later to put off the crash, and then I don’t sleep and function so poorly for the next couple of days that I might as well be unmedicated
AngelEyesTx
in
CHADD's Adult ADHD Support
2 years ago
Stimulants and non stimulant combo question..
Does anyone have any information regarding the combination therapy of Clonidine with a stimulant? *** Geeky medication question warning *** To be specific, I want to understand how Clonidines mechanism of action (post and pre synapitally attentuating NE) works if stimulant therapy is initiated with
Does anyone have any information regarding the combination therapy of Clonidine with a stimulant? *** Geeky medication question warning *** To be specific, I want to understand how Clonidines mechanism of action (post and pre synapitally attentuating NE) works if stimulant therapy is initiated with
Bootsie1
in
CHADD's ADHD Parents Together
2 years ago
Tricyclic antidepressants , amitriptyline in particular, delay the need for dopaminergic therapy in early Parkinson’s disease.
Individuals taking tricyclics antidepressants (amitriptyline in particular) had a lower probability of initiating dopaminergic therapy within the first year of their study. This observation suggested to the researchers that treatment with tricyclic antidepressants may delay the need to initiate dopamine
Individuals taking tricyclics antidepressants (amitriptyline in particular) had a lower probability of initiating dopaminergic therapy within the first year of their study. This observation suggested to the researchers that treatment with tricyclic antidepressants may delay the need to initiate dopamine
Little_apple
in
Cure Parkinson's
2 years ago
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