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Dopamine
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What does GPT4 have to say about the role of inflammation in RLS?
This was the answer I got: "Chronic inflammation can contribute to the dysfunction of the
dopamine
system by damaging the dopaminergic neurons in the brain. This can lead to a reduction in
dopamine
levels, which can cause the symptoms of RLS.
This was the answer I got: "Chronic inflammation can contribute to the dysfunction of the
dopamine
system by damaging the dopaminergic neurons in the brain. This can lead to a reduction in
dopamine
levels, which can cause the symptoms of RLS.
Eryl
in
Restless Legs Syndrome
1 year ago
Phellodendron - MAO-B - Dopamine - Relora
MAO-B is an enzyme which breaks down
dopamine
. Our levels of the 'feel-good' neurotransmitter decline about 13% per decade after age 45. MAO-B is also a target in Parkinson's & Alzheimer's.
MAO-B is an enzyme which breaks down
dopamine
. Our levels of the 'feel-good' neurotransmitter decline about 13% per decade after age 45. MAO-B is also a target in Parkinson's & Alzheimer's.
pjoshea13
in
Fight Prostate Cancer
1 year ago
Found something that is helping so far!
Wellbutrin blocks the reuptake of
dopamine
and norepinephrine, and more
dopamine
means more focus for us! I’ve been taking it about two weeks but felt different within a few days.
Wellbutrin blocks the reuptake of
dopamine
and norepinephrine, and more
dopamine
means more focus for us! I’ve been taking it about two weeks but felt different within a few days.
BlessedNeuroDiverse
in
CHADD's Adult ADHD Support
1 year ago
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Augmentation Concerns Being Overblown?
“A second common adverse effect of long-term
dopamine
agonist use is [u]impulse control disorder, with rate of occurrence estimated to be between 6% and 17%[/u].
“A second common adverse effect of long-term
dopamine
agonist use is [u]impulse control disorder, with rate of occurrence estimated to be between 6% and 17%[/u].
ircam2112
in
Restless Legs Syndrome
1 year ago
Mum newly diagnosed with MSA-P and we are all struggling
She started to loose strength on her right side, with Bradykinesia and we sent her for investigations as they weren’t sure whether it was a stroke etc but after 5 months to get results the DAT scan showed lack of
dopamine
.
She started to loose strength on her right side, with Bradykinesia and we sent her for investigations as they weren’t sure whether it was a stroke etc but after 5 months to get results the DAT scan showed lack of
dopamine
.
Purplestar2
in
Multiple System Atrophy Trust
1 year ago
Seeking advice for changing from Temgesic to Gabapentin for treating my refractory RLS.
I have suffered with Restless legs for 52 years now and have been through the hell of being on
dopamine
agonist medication and experiencing augmentation. I have asked my new doctor to do some research into the latest research on RLS.
I have suffered with Restless legs for 52 years now and have been through the hell of being on
dopamine
agonist medication and experiencing augmentation. I have asked my new doctor to do some research into the latest research on RLS.
Jules1953
in
Restless Legs Syndrome
1 year ago
Malabsorption of drugs?
I am still awaiting a diagnosis of PA, but do suspect I do have it. My stomach pH level was recently 8.1, so very low stomach acid, which is why I am not absorbing/processing B12, iron and folate. I also did a test which showed I have very low diamine oxidase in my gut so have histamine intolerance.
I am still awaiting a diagnosis of PA, but do suspect I do have it. My stomach pH level was recently 8.1, so very low stomach acid, which is why I am not absorbing/processing B12, iron and folate. I also did a test which showed I have very low diamine oxidase in my gut so have histamine intolerance.
Chickens44
in
Pernicious Anaemia Society
2 months ago
Stopped taking mood supplement, SAM-e...is that WHY I'm struggling?🤔🧐🤨
SAMe plays a role in the immune system, maintains cell membranes, and helps produce and break down brain chemicals, such as serotonin, melatonin, and
dopamine
. It works with vitamin B12 and folate (vitamin B9). Being deficient in either vitamin B12 or folate may reduce levels of SAMe in your body.
SAMe plays a role in the immune system, maintains cell membranes, and helps produce and break down brain chemicals, such as serotonin, melatonin, and
dopamine
. It works with vitamin B12 and folate (vitamin B9). Being deficient in either vitamin B12 or folate may reduce levels of SAMe in your body.
LifeIsThePitts
in
Anxiety and Depression Support
1 year ago
Extreme headache and always feeling feverish. I don't think I can get my exam feeling like that
I guess i need to stop accepting help from this region as they take advantage of me needing help, play my
dopamine
, play hot and cold and then dissapear. A b c d e f..orget em. There are better people. I had totally lost hope then i got cute message here. Thank you.
I guess i need to stop accepting help from this region as they take advantage of me needing help, play my
dopamine
, play hot and cold and then dissapear. A b c d e f..orget em. There are better people. I had totally lost hope then i got cute message here. Thank you.
Against_the_current
in
Anxiety and Depression Support
1 year ago
Has anyone experienced benefits from coq10
According to the following article Comparing the youngest age people to the oldest, the number of striatal
dopamine
transporters was cut by 46%, or 6.6% per decade of life.3 The rate of loss of
dopamine
transporters is accelerated in Parkinson's patients, and this age-related factor may suggest why
According to the following article Comparing the youngest age people to the oldest, the number of striatal
dopamine
transporters was cut by 46%, or 6.6% per decade of life.3 The rate of loss of
dopamine
transporters is accelerated in Parkinson's patients, and this age-related factor may suggest why
Farooqji
in
Cure Parkinson's
1 year ago
probiotics
In any case I believe my issue is a combination of low brain
dopamine
and either down regulated GABA receptors or receptors that just don’t function well. I have definitely kept track of my trigger foods and try to avoid MSG, processed foods, and super high oxalate foods.
In any case I believe my issue is a combination of low brain
dopamine
and either down regulated GABA receptors or receptors that just don’t function well. I have definitely kept track of my trigger foods and try to avoid MSG, processed foods, and super high oxalate foods.
Insomniac88
in
Restless Legs Syndrome
8 months ago
Edited: PD increases chance of RLS.(yes) Azilect worsens RLS.(wrong) Ambroxol, being an antihistamine I believe worsens RLS.(incorrect)
Editing my edit: (yes, I know, but I’m trying) Not only do
dopamine
agonists make RLS worse but so do meds that increase
dopamine
. Azilect was not mentioned specifically but increasing
dopamine
is a “cause of RLS augmentation.” Levodopa increases augmentation meaning it makes RLS worse.
Editing my edit: (yes, I know, but I’m trying) Not only do
dopamine
agonists make RLS worse but so do meds that increase
dopamine
. Azilect was not mentioned specifically but increasing
dopamine
is a “cause of RLS augmentation.” Levodopa increases augmentation meaning it makes RLS worse.
Little_apple
in
Cure Parkinson's
1 year ago
My husbands latest poem, called ‘ French Dressing’
With a
dopamine
pill, it may become still. The shampoo is gel it’s so hard to tell I have to confess that I needed much less There’s masses of foam, will it muck up the chrome? At last I am done it’s not been much fun. When did my clothes become sticky and putting them on was more tricky.
With a
dopamine
pill, it may become still. The shampoo is gel it’s so hard to tell I have to confess that I needed much less There’s masses of foam, will it muck up the chrome? At last I am done it’s not been much fun. When did my clothes become sticky and putting them on was more tricky.
Zella23
in
Cure Parkinson's
1 year ago
Onset/diagnosis after years
DBS did not have the desired effect; my aunt has electrodes in her brain that stimulate
dopamine
production. After a couple of years of struggling, doctors couldn't make a good diagnosis, left between parkinsonism A typical and msa. At this point, my aunt is hooked up to an apomorphine pump.
DBS did not have the desired effect; my aunt has electrodes in her brain that stimulate
dopamine
production. After a couple of years of struggling, doctors couldn't make a good diagnosis, left between parkinsonism A typical and msa. At this point, my aunt is hooked up to an apomorphine pump.
Paulaaaa
in
PSP Association
1 year ago
256+ Ways To Increase Dopamine Naturally (Supplements And Genetics)
https://mybiohack.com/blog/all-ways-increase-
dopamine
-naturally
https://mybiohack.com/blog/all-ways-increase-
dopamine
-naturally
Farooqji
in
Cure Parkinson's
1 year ago
Treatment for fibro, MCAS, hypermobility syndrom (after catching covid) and long term covid sufferers
Good afternoon to all. I wanted to go straight to the findings I have done, diagnostic tests with top consultants in London. I was diagnosed with hypermobility syndrome and I had a horrible reaction to a covid infection last xmas which caused me long covid: fatigue, pain in bones, muscles and joints,
Good afternoon to all. I wanted to go straight to the findings I have done, diagnostic tests with top consultants in London. I was diagnosed with hypermobility syndrome and I had a horrible reaction to a covid infection last xmas which caused me long covid: fatigue, pain in bones, muscles and joints,
Divinesoul
in
Fibromyalgia Action UK
3 months ago
Neupro patch advice
It is also a
dopamine
drug and I am so tired I couldn't even recall good or bad but recall some having problems with it. I went with the Gabepentin for now as I have a Mayo referral. Just want some advise from all of you who know from experience. I am just so frustrated with my current Neuro!
It is also a
dopamine
drug and I am so tired I couldn't even recall good or bad but recall some having problems with it. I went with the Gabepentin for now as I have a Mayo referral. Just want some advise from all of you who know from experience. I am just so frustrated with my current Neuro!
Aujamw
in
Restless Legs Syndrome
1 year ago
REFERRAL TO NEUROLOGIST
Has anyone been through the transition from
dopamine
agonists and can you share your experiences please? Many thanks, Alan
Has anyone been through the transition from
dopamine
agonists and can you share your experiences please? Many thanks, Alan
albax
in
Restless Legs Syndrome
1 year ago
Seratonin for resting tremor : could tremor that doesn’t respond to just dopamine need more seratonin?
So low seratonin kicks off the loop or cascade that culminates in low
dopamine
. Would increasing seratonin have a disease modifying affect or just aid in more
dopamine
and reduce symptoms?
So low seratonin kicks off the loop or cascade that culminates in low
dopamine
. Would increasing seratonin have a disease modifying affect or just aid in more
dopamine
and reduce symptoms?
Little_apple
in
Cure Parkinson's
1 year ago
RLS and iron metabolism and treating with dopamine agonists causes dopamine burnout
And, I now think the
dopamine
agonists are prodding the tired
dopamine
receptors until they die instead of nurturing them back to health.)
And, I now think the
dopamine
agonists are prodding the tired
dopamine
receptors until they die instead of nurturing them back to health.)
Little_apple
in
Cure Parkinson's
1 year ago
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