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Dopamine
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Goats milk kefir
Hi, Does anyone drink Chuckling Goat kefir? I have had some on and off over the last few weeks, but not consistently so not sure if it helps. It is a very strong kefir that is full of B12. I am not sure yet if I have pernicious anaemia, or whether it is a gut dysbiosis problem as I do not appear to be
Hi, Does anyone drink Chuckling Goat kefir? I have had some on and off over the last few weeks, but not consistently so not sure if it helps. It is a very strong kefir that is full of B12. I am not sure yet if I have pernicious anaemia, or whether it is a gut dysbiosis problem as I do not appear to be
Chickens44
in
Pernicious Anaemia Society
4 months ago
Iron metabolism in RLS : iron transporter ferroportin & Magnesium Malate
And, I now think the
dopamine
agonists are prodding the tired
dopamine
receptors until they die instead of nurturing them back to health.)
And, I now think the
dopamine
agonists are prodding the tired
dopamine
receptors until they die instead of nurturing them back to health.)
Little_apple
in
Restless Legs Syndrome
1 year ago
Daily consumption of methylene blue reduces attentional deficits and dopamine reduction in a 6-OHDA model of Parkinson’s disease
https://www.mwhp.com/methylene-blue-and-red-light-therapy-for-dementia-parkinsons-and-alzheimers-disease/ -------------------------------------------- I never heard of "methylene blue" until 15 minutes ago while watching this Dr. Berg video. He says you can buy it over the counter! https://youtu.be
https://www.mwhp.com/methylene-blue-and-red-light-therapy-for-dementia-parkinsons-and-alzheimers-disease/ -------------------------------------------- I never heard of "methylene blue" until 15 minutes ago while watching this Dr. Berg video. He says you can buy it over the counter! https://youtu.be
PDWarrior1900
in
Cure Parkinson's
1 year ago
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Current Status and Future Perspectives on Stem Cell-Based Therapies for Parkinson’s Disease
The loss of a specific cell type, midbrain
dopamine
neurons in the substantia nigra, is the main cause of motor dysfunction in PD.
The loss of a specific cell type, midbrain
dopamine
neurons in the substantia nigra, is the main cause of motor dysfunction in PD.
Baron1
in
Cure Parkinson's
1 year ago
Titrating off of Ropinirole
Is it caused by DAWS and the lack of
dopamine
or is it a side effect of the Buprenorphine that I'm taking? Is there anything that might relieve the mental issues. Sorry for such a long letter. And thanks so much for all your help. Chris
Is it caused by DAWS and the lack of
dopamine
or is it a side effect of the Buprenorphine that I'm taking? Is there anything that might relieve the mental issues. Sorry for such a long letter. And thanks so much for all your help. Chris
climber54
in
Restless Legs Syndrome
1 year ago
Research Funding
A case in point is Dr Jonathan Sackner-Bernstein, whose proposition that a
Dopamine
excess within Doperminergic neurons might be toxic and thus responsible for their demise, meets possibly understandable resistance from the long standing neurological orthodoxy.
A case in point is Dr Jonathan Sackner-Bernstein, whose proposition that a
Dopamine
excess within Doperminergic neurons might be toxic and thus responsible for their demise, meets possibly understandable resistance from the long standing neurological orthodoxy.
Hidden
in
Cure Parkinson's
1 year ago
Alternating meds
My case is very severe with many previous pharmacologic failures including Alpha 2 Ligands, Buprenorphine and other painkillers, Dipyridamole, full time
dopamine
agonists, diet, and holistic management.
My case is very severe with many previous pharmacologic failures including Alpha 2 Ligands, Buprenorphine and other painkillers, Dipyridamole, full time
dopamine
agonists, diet, and holistic management.
WelbyB
in
Restless Legs Syndrome
1 year ago
What to try next?
The neurologist prescribed a low dose of an oral
dopamine
agonist but it made him too sleepy. He is now offering a choice between trying Artane, or a Neupro (
dopamine
agonist) patch, perhaps left on only during the day, or commencing low dose Madopar. Does the community have thoughts on this?
The neurologist prescribed a low dose of an oral
dopamine
agonist but it made him too sleepy. He is now offering a choice between trying Artane, or a Neupro (
dopamine
agonist) patch, perhaps left on only during the day, or commencing low dose Madopar. Does the community have thoughts on this?
goldengrove
in
Cure Parkinson's
1 year ago
“The three amino acids that are most effective at increasing dopamine levels are l-tyrosine, L-dopa, and phenylalanine.”
I’m learning other means of increasing
dopamine
to wean off of Azilect.
I’m learning other means of increasing
dopamine
to wean off of Azilect.
Little_apple
in
Cure Parkinson's
1 year ago
augmentation on neupro+Gabapentin. should I switch to a different dopamine agonist? All that’s helping is cannabis.
He said his patients tend to need a
dopamine
agonist. What does the research say regarding moving from one DA to another? Would it be worthwhile to try shifting to Requip (ropinirole) ER? I read it’s a 24hr release pill.
He said his patients tend to need a
dopamine
agonist. What does the research say regarding moving from one DA to another? Would it be worthwhile to try shifting to Requip (ropinirole) ER? I read it’s a 24hr release pill.
Discopage
in
Restless Legs Syndrome
1 year ago
Advice on non-medication treatment of RLS required
A neurologist I saw recently wanted to put me on
dopamine
-agonist patches which I refused, tho' I am following her recommended course of B12 injections. I've had 9 of the 12 jabs prescribed and I find my symptoms have been reduced to some extent and my sleep quality has been improved.
A neurologist I saw recently wanted to put me on
dopamine
-agonist patches which I refused, tho' I am following her recommended course of B12 injections. I've had 9 of the 12 jabs prescribed and I find my symptoms have been reduced to some extent and my sleep quality has been improved.
argyll1
in
Restless Legs Syndrome
8 months ago
blood sugar levels
I read that levodopa carbadopa increases your blood level of glucose does anyone take any non-
dopamine
therapy that works when I take levadopa I can’t stand up. And all of my te tendons, get weak and burn. I also have Lyme disease I’ll read that to her and
dopamine
enhance Lyme disease.
I read that levodopa carbadopa increases your blood level of glucose does anyone take any non-
dopamine
therapy that works when I take levadopa I can’t stand up. And all of my te tendons, get weak and burn. I also have Lyme disease I’ll read that to her and
dopamine
enhance Lyme disease.
Marcia123
in
Cure Parkinson's
1 year ago
Stopping Azilect to change to Macuna? I need help.
So please, has anyone had success with macuna to increase
dopamine
and stop or reduce internal tremors and RLS? quote “Thus, for some, long-term use of
dopamine
agonists results in much worse RLS than before treatment, a condition referred to as RLS augmentation.
So please, has anyone had success with macuna to increase
dopamine
and stop or reduce internal tremors and RLS? quote “Thus, for some, long-term use of
dopamine
agonists results in much worse RLS than before treatment, a condition referred to as RLS augmentation.
Little_apple
in
Cure Parkinson's
1 year ago
Anyone else have a Skin Biopsy?
Scan showed lowered
dopamine
levels. I had mild symptoms including. Bradykinesia, rigidity, masking and dystonia. primarily in the left foot.I don’t have visible tremors.yet . Didn’t respond well to C/L( lots of off time). . Symptoms have worsened.
Scan showed lowered
dopamine
levels. I had mild symptoms including. Bradykinesia, rigidity, masking and dystonia. primarily in the left foot.I don’t have visible tremors.yet . Didn’t respond well to C/L( lots of off time). . Symptoms have worsened.
BeachcomberFL
in
Cure Parkinson's
1 year ago
NURR1
In particular, the team found that the naturally occurring molecule 5,6-dihydroxyindole (DHI), a
dopamine
metabolite, binds directly to and modulates the activity of Nurr1. https://parkinsonsnewstoday.com/news/new-parkinsons-strategy-targets-nurr1-protein/
In particular, the team found that the naturally occurring molecule 5,6-dihydroxyindole (DHI), a
dopamine
metabolite, binds directly to and modulates the activity of Nurr1. https://parkinsonsnewstoday.com/news/new-parkinsons-strategy-targets-nurr1-protein/
Little_apple
in
Cure Parkinson's
1 year ago
St. John’s wort, ursolic acid, Gardenia jasminoides
My guess is it’s because of his
dopamine
beta hydroxylase running fast, (genetic testing picked this up) breaking down the
dopamine
too fast so it runs out too quickly and causes rigidity and anxiety.
My guess is it’s because of his
dopamine
beta hydroxylase running fast, (genetic testing picked this up) breaking down the
dopamine
too fast so it runs out too quickly and causes rigidity and anxiety.
LAJ12345
in
Cure Parkinson's
1 year ago
Safinamide
3) trial a
dopamine
agonist (eg ropinerole) - am less keen on this course of action has anyone else had any experience that might help me better understand what options are the most likely to help.
3) trial a
dopamine
agonist (eg ropinerole) - am less keen on this course of action has anyone else had any experience that might help me better understand what options are the most likely to help.
Tomkins
in
Cure Parkinson's
1 year ago
IRL1117, Potential Improvement on Levodopa, May Enter Clinical Trial
IRLAB Therapeutics has selected a
dopamine
receptor agonist candidate called IRL1117 to advance as a Parkinson’s disease treatment, potentially as a longer-lasting alternative to levodopa with lesser side effects.
IRLAB Therapeutics has selected a
dopamine
receptor agonist candidate called IRL1117 to advance as a Parkinson’s disease treatment, potentially as a longer-lasting alternative to levodopa with lesser side effects.
Farooqji
in
Cure Parkinson's
1 year ago
Be careful with B6/P5P
It’s weird because I know b6 is vital in making
dopamine
, but too much is like not having enough.
It’s weird because I know b6 is vital in making
dopamine
, but too much is like not having enough.
38yroldmale
in
Cure Parkinson's
1 year ago
ChatGPT and Restless legs
Dopamine
agonists: These medications increase
dopamine
levels in the brain to reduce symptoms. Examples include pramipexole (Mirapex) and ropinirole (Requip). 2. Iron supplements: Iron deficiency can worsen restless leg syndrome symptoms, so iron supplements may be recommended. 3.
Dopamine
agonists: These medications increase
dopamine
levels in the brain to reduce symptoms. Examples include pramipexole (Mirapex) and ropinirole (Requip). 2. Iron supplements: Iron deficiency can worsen restless leg syndrome symptoms, so iron supplements may be recommended. 3.
thorp
in
Restless Legs Syndrome
1 year ago
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