Experiences with

Dopamine

https://articles.mercola.com/sites/articles/archive/2024/10/16/dopamine-breast-cancer.aspx?

TLDR; *Dopamine is a motivator. Not a reward. *Emotionally being dysregulated messes with this ie Dopamine pathways *fix ED helps with fix Dopamine balance. [*then a plug for a course I'd love a day a week to read, listen think on all this stuff. Cheers

If you would like to join my dopamine club, just submit one natural dopamine generating action that works for you. You’re in!😁🥸😫

redirectedFrom=fulltext This study shows a reduction in serum a syn levels in RLS patients and suggests that it may be the reason for reduced dopamine/faulty dopamine system in RLS patients. It also mentions that a high percentage are experiencing augmentation. What a surprise!

Miller, PhD, a professor at Columbia University, will assess how to prevent further damage of dopamine-producing neurons by levodopa and its derivatives. Levodopa is the precursor of dopamine and a gold standard therapy for Parkinson’s that effectively reduces early motor symptoms.

Another Nail in the coffin of Dopamine Agonists . Study centralised on Parkinsons , but probably not enough research done with RLS patients https://jnnp.bmj.com/content/88/8/A19.2

All patients were treated with dopamine agonists! Even though some showed signs of anaemia & could have resolved symptoms with iron therapy. We clearly have a long, long way to go in stopping dopamine agonists as first line treatment. https://www.wjgnet.com/2222-0682/full/v15/i1/97171.htm

But for people who already have high dopamine levels (or whose neurons are too sensitive to dopamine), this leads to dopamine neurotoxicity—in simple terms, brain neurons get damaged by excess dopamine.

Has anyone managed to reduce or replace their dopamine agonist medication and if so, how and with what? Many thanks.

But I am worried about it affecting dopamine levels or blocking dopamine. I am looking to add to my stack of supplements.

A useful article on the dangers of dopamine agonists. Hopefully some doctors will actually read it. https://mol.im/a/13877837

I want to hear if you have used or using this dopamine supplement. Which one do you take? powder or L-dopa capsule? How it's effect your brain?

It's been used to revitalize/repair/bring back dopamine system to homeostasis for several conditions including RLS. Has anyone tried or heard of it? I'm thinking it could be especially helpful for DAWS (coming off dopamine agonist meds).

Are they both Dopamine Antagonists?

https://www.sciencedirect.com/science/article/abs/pii/S0022510X24002569 A new study on refractory RLS recommends NOT starting young patients on dopamine agonists. Hopefully, we will start to see more and more of these studies and they will condemn the use of dopamine agonists.

https://www.msn.com/en-gb/health/other/dopamine-discovery-brain-chemical-s-role-in-social-understanding-offers-new-hope-for-treatments/ar-BB1pD4lp?ocid=tweet

Here is my question, pramipexole is a dopamine agonist and my doctor has prescribed wellbutrin which is a dopamine reuptake inhibitor. I haven't started taking the wellbutrin yet, I thought would be best if run this question by the very knowledgable here first.

Definition here; https://en.m.wikipedia.org/wiki/Dopamine_dysregulation_syndrome How can docs be sure? A lot of the alleged "symptoms" would be entirely understandable from someone denied a medication that helps...and I don't get anything like euphoria from taking it...just a cessation of physical symptoms

This finding challenges the long-held belief that dopamine is the only key player in motor control. Researchers are now exploring how to use ophthalmic acid as a potential treatment for movement disorders, offering hope for more effective therapies.

I am concerned the alpha-gpc might be counterproductive to dopamine levels. Can you advise?