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Augmentation
In my years with PLMD, I have taken almost everything, but not
dopamine
agonists. Is it correct that if you start and have success at a low dose -- and never increase it -- that you could avoid augmentation?
In my years with PLMD, I have taken almost everything, but not
dopamine
agonists. Is it correct that if you start and have success at a low dose -- and never increase it -- that you could avoid augmentation?
wantokporo
in
Restless Legs Syndrome
11 months ago
My IBS Team Sheet – Fun and Games (How it helps me manage my IBS)
I know that when I do play a game each day, my brain releases a positive happiness hormone (chemical) called
Dopamine
. I also know that the release of this hormone will help me with managing my IBS in that I get fewer flare ups!
I know that when I do play a game each day, my brain releases a positive happiness hormone (chemical) called
Dopamine
. I also know that the release of this hormone will help me with managing my IBS in that I get fewer flare ups!
MountainHare1
in
IBS Network
4 months ago
Roprinerole Withdrawl
My
dopamine
receptors are probably destroyed and am not looking forward to the upcoming reductions of Roprinerole. Any other suggestions? Thank you so much.
My
dopamine
receptors are probably destroyed and am not looking forward to the upcoming reductions of Roprinerole. Any other suggestions? Thank you so much.
Washguy731
in
Restless Legs Syndrome
9 months ago
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Advice needed
I have been on
Dopamine
meds since 2010 and am presently on 2mg Neupro patch which I was switched to in 2016 by a Neurologist. The inevitable Augmentation is now so bad I need to come off it.
I have been on
Dopamine
meds since 2010 and am presently on 2mg Neupro patch which I was switched to in 2016 by a Neurologist. The inevitable Augmentation is now so bad I need to come off it.
Annieapple
in
Restless Legs Syndrome
10 months ago
FINALLY found a scientific study that supports my theory about Brain Iron and Serum Iron. Finally!!!
What’s really odd to me is that not only do we have a larger reservoir of unprocessed
dopamine
than the average bear, but per the above quote, we also have a larger reservoir of serum iron? Any theorys out there?
What’s really odd to me is that not only do we have a larger reservoir of unprocessed
dopamine
than the average bear, but per the above quote, we also have a larger reservoir of serum iron? Any theorys out there?
DesertOasis
in
Restless Legs Syndrome
6 months ago
A cross in the sand
It appears that a person with PD has no
dopamine
supply, but it can be stimulated with levadopa, which is a great help. But when there is an abrupt end to the meds, the body goes into stress and manifests dyskinesia which is worsening the original problem.
It appears that a person with PD has no
dopamine
supply, but it can be stimulated with levadopa, which is a great help. But when there is an abrupt end to the meds, the body goes into stress and manifests dyskinesia which is worsening the original problem.
Meg024
in
Cure Parkinson's
10 months ago
Looking for comments on this opening info sheet.
There is a group of approved medication for the management of RLS in Australia -
dopamine
agonists (Rotigotine,Pramipexol, Ropinirole). They can significantly improve the symptoms of RLS in most users.
There is a group of approved medication for the management of RLS in Australia -
dopamine
agonists (Rotigotine,Pramipexol, Ropinirole). They can significantly improve the symptoms of RLS in most users.
RLSLearner
in
Restless Legs Syndrome
4 months ago
For a good time.... call Dopamine T-shirt
This is a molecule of
Dopamine
resembling a lady. Her face is a benzene ring, her eyebrows and mouth are double bonds, her earrings are hydroxy groups, and the pendant on her necklace is an amine group. The phone number is actually the Chemical Abstracts number for the
dopamine
molecule.
This is a molecule of
Dopamine
resembling a lady. Her face is a benzene ring, her eyebrows and mouth are double bonds, her earrings are hydroxy groups, and the pendant on her necklace is an amine group. The phone number is actually the Chemical Abstracts number for the
dopamine
molecule.
DeanGreen
in
Cure Parkinson's
1 year ago
On the Holistic origin of Parkinson's
The process would detect the origin event that gave rise to the disorder in each patient and could be a key factor in reducing the intensity of fear and with it the unconscious recognition that the
dopamine
production system can now be restored because the possibility of living another traumatic event
The process would detect the origin event that gave rise to the disorder in each patient and could be a key factor in reducing the intensity of fear and with it the unconscious recognition that the
dopamine
production system can now be restored because the possibility of living another traumatic event
ManuCalma
in
Cure Parkinson's
7 months ago
Dystonia: WTF?!
This dystonia now, if I’m really low on
dopamine
, attacks my stomach, feet, back muscles, neck - and as I witnessed during my ‘no drugs allowed’ period - my jaw. When this strikes I’m in a truly awful state and need to be rescued with the Madopar that I mentioned above.
This dystonia now, if I’m really low on
dopamine
, attacks my stomach, feet, back muscles, neck - and as I witnessed during my ‘no drugs allowed’ period - my jaw. When this strikes I’m in a truly awful state and need to be rescued with the Madopar that I mentioned above.
jeeves19
in
Cure Parkinson's
9 months ago
Augmentation
Hi, I am trying to come off the
dopamine
agonist that I have been taking for the past eight years for my RLS, does anybody know if the augmentation I have built up will go when I am clear of the medication, or am I stuck with it for the rest of my life?
Hi, I am trying to come off the
dopamine
agonist that I have been taking for the past eight years for my RLS, does anybody know if the augmentation I have built up will go when I am clear of the medication, or am I stuck with it for the rest of my life?
Mounta
in
Restless Legs Syndrome
11 months ago
Confusion over Mayo Clinic report
Reading the report, it seems the next recommendation is the nonergot
dopamine
agonists, or the drugs that cause augmentation. Sue Johnson, etc. seem to disagree about this course of action?
Reading the report, it seems the next recommendation is the nonergot
dopamine
agonists, or the drugs that cause augmentation. Sue Johnson, etc. seem to disagree about this course of action?
wantokporo
in
Restless Legs Syndrome
11 months ago
blood test back - any thoughts?
Also my white blood count came back as much lower (3.6 vs 5 last year) - do any
dopamine
or prefab affect blood results? Just curious about the drop. Thanks as always for all your support in getting this far.
Also my white blood count came back as much lower (3.6 vs 5 last year) - do any
dopamine
or prefab affect blood results? Just curious about the drop. Thanks as always for all your support in getting this far.
Phantom38
in
Restless Legs Syndrome
11 months ago
Mitochondrial failing due to T3 problems
I have also read that - • Prolonged administration of pharmacological doses of
dopamine
can significantly reduce serum TSH levels and thyroid hormone secretion in normal and critically ill subjects. I have been taking
dopamine
agonists for years.
I have also read that - • Prolonged administration of pharmacological doses of
dopamine
can significantly reduce serum TSH levels and thyroid hormone secretion in normal and critically ill subjects. I have been taking
dopamine
agonists for years.
Simonron
in
Thyroid UK
11 months ago
What are ‘off’ periods – and how can they impact people with Parkinson’s disease?
“The ‘off’ state can kick in when levodopa is eliminated from our body – and people begin to express motor symptoms that are related to the low amount of
dopamine
going to the brain.”
“The ‘off’ state can kick in when levodopa is eliminated from our body – and people begin to express motor symptoms that are related to the low amount of
dopamine
going to the brain.”
Farooqji
in
Cure Parkinson's
10 months ago
Bayer Investing in New Cell Therapy Facility
About bemdaneprocel and Parkinson’s Disease Bemdaneprocel (BRT-DA01) is an investigational cell therapy designed to replace the
dopamine
producing neurons that are lost in Parkinson’s disease.
About bemdaneprocel and Parkinson’s Disease Bemdaneprocel (BRT-DA01) is an investigational cell therapy designed to replace the
dopamine
producing neurons that are lost in Parkinson’s disease.
redhawk1
in
Cure Parkinson's
6 months ago
Reducing Augmentation
https://sleepreviewmag.com/sleep-disorders/movement-disorders/restless-legs-syndrome/reduce-augmentation-risk-restless-legs-syndrome/ A useful article on
Dopamine
Agonists and augmentation by Dr William Ondo.
https://sleepreviewmag.com/sleep-disorders/movement-disorders/restless-legs-syndrome/reduce-augmentation-risk-restless-legs-syndrome/ A useful article on
Dopamine
Agonists and augmentation by Dr William Ondo.
Joolsg
in
Restless Legs Syndrome
1 year ago
Dopamine a key factor in whether people find exercise easy or hard
https://www.diabetes.co.uk/news/2023/apr/
dopamine
-a-key-factor-in-whether-people-find-exercise-easy-or-hard.html
https://www.diabetes.co.uk/news/2023/apr/
dopamine
-a-key-factor-in-whether-people-find-exercise-easy-or-hard.html
Farooqji
in
Cure Parkinson's
1 year ago
Why I pay no attention to studies of PD in mice.
Perhaps the current rodent models of PD would be more predictive of what will translate into human studies if the time course of
dopamine
neuron degeneration could be mimicked and behavioral tests were designed to assess the more subtle symptoms ... ” “… Perhaps one of the most relevant examples … with
Perhaps the current rodent models of PD would be more predictive of what will translate into human studies if the time course of
dopamine
neuron degeneration could be mimicked and behavioral tests were designed to assess the more subtle symptoms ... ” “… Perhaps one of the most relevant examples … with
MBAnderson
in
Cure Parkinson's
8 months ago
Could Psychedelics help in Parkinsons Disease treatment?
- Symptom management - Some research indicates psychedelics may protect
dopamine
neurons or stimulate growth of new ones. Reopening plasticity periods could enhance this through combined psychedelic and neurostimulation therapies.
- Symptom management - Some research indicates psychedelics may protect
dopamine
neurons or stimulate growth of new ones. Reopening plasticity periods could enhance this through combined psychedelic and neurostimulation therapies.
pdpatient
in
Cure Parkinson's
8 months ago
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