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Toxicological Effects of Berberine and Sanguinarine 2018
biosynthesis, accompanied by reduced levels of norepinephrine (NE) and
dopamine
(DA) (Kwon et al., 2010)."
biosynthesis, accompanied by reduced levels of norepinephrine (NE) and
dopamine
(DA) (Kwon et al., 2010)."
Bolt_Upright
in
Cure Parkinson's
1 year ago
Method generates dopaminergic neurons lost in Parkinson’s disease
Researchers in Canada have developed a new method to generate functional dopaminergic neurons, the
dopamine
-producing nerve cells lost in Parkinson’s disease, from human pluripotent stem cells (hPSC).
Researchers in Canada have developed a new method to generate functional dopaminergic neurons, the
dopamine
-producing nerve cells lost in Parkinson’s disease, from human pluripotent stem cells (hPSC).
Baron1
in
Cure Parkinson's
3 months ago
Severe RLS, non pharmacological healing attempts, and a recent bipolar 2 diagnosis
I’m currently researching the
dopamine
theory (as
dopamine
issues relate to bipolar and to work-related burnout too) and inflammation, and doing all I can in my day to day life to improve these areas to see if it helps. I’m worried I’ve missed something obvious along the way.
I’m currently researching the
dopamine
theory (as
dopamine
issues relate to bipolar and to work-related burnout too) and inflammation, and doing all I can in my day to day life to improve these areas to see if it helps. I’m worried I’ve missed something obvious along the way.
Cabinman
in
Restless Legs Syndrome
6 months ago
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Hallucination side effect & Medication Management
Mirapex none, added SEROquel for hallucinations (didn't do anything, hallucinations still here, even more so, sleeping less bc of the hallucinations, swelling continues and in pain) --- Doc is adamant that the
dopamine
agonist (Mirapex) is the one causing hallucinations + swelling, but my dad HAS those
Mirapex none, added SEROquel for hallucinations (didn't do anything, hallucinations still here, even more so, sleeping less bc of the hallucinations, swelling continues and in pain) --- Doc is adamant that the
dopamine
agonist (Mirapex) is the one causing hallucinations + swelling, but my dad HAS those
daughter-Advocate
in
Cure Parkinson's
1 year ago
Dopamine Stem Cell Replacement for Parkinson's - SUMMARY and LONG videos
The short video was released May 7, 2023 summarizing the full presentation which was video'd on February 23, 2023 ------------------------------------------------ https://youtu.be/QZuqXjXtBuo --------------------------------------------- FULL one hour, 11 minute presentation here: https://youtu.be
The short video was released May 7, 2023 summarizing the full presentation which was video'd on February 23, 2023 ------------------------------------------------ https://youtu.be/QZuqXjXtBuo --------------------------------------------- FULL one hour, 11 minute presentation here: https://youtu.be
PDWarrior1900
in
Cure Parkinson's
1 year ago
Sleepy kidney
I spent a week in ITU and was hooked up to
dopamine
for 3 weeks to help my blood pressure. My urine out has been slow, for a few days I got between 600-800ml but now am back down between 200- 300ml a day. GFR ranging between 10- 15. And creatine rising to between 350 - 400 if I don't diaylize.
I spent a week in ITU and was hooked up to
dopamine
for 3 weeks to help my blood pressure. My urine out has been slow, for a few days I got between 600-800ml but now am back down between 200- 300ml a day. GFR ranging between 10- 15. And creatine rising to between 350 - 400 if I don't diaylize.
Gwenkidney
in
Kidney Transplant Patient Support
1 year ago
Anyone tried Black Seed Oil?
Immunohistochemical analysis revealed
dopamine
neuron loss in the SNc area and decreased
dopamine
transporters in the striatum following MPTP administration. However, TQ treatment significantly rescued dopaminergic neuronal loss and
dopamine
transporters.
Immunohistochemical analysis revealed
dopamine
neuron loss in the SNc area and decreased
dopamine
transporters in the striatum following MPTP administration. However, TQ treatment significantly rescued dopaminergic neuronal loss and
dopamine
transporters.
John_morris71
in
Cure Parkinson's
1 year ago
‘World's 1st' fetal brain stem cell transplant effective in Parkinson's disease: study
Cell replacement therapy makes
dopamine
nerve precursor cells from stem cells derived from the midbrain of the fetus. Then,
dopamine
nerve precursor cells can be transplanted into the patient's brain.
Cell replacement therapy makes
dopamine
nerve precursor cells from stem cells derived from the midbrain of the fetus. Then,
dopamine
nerve precursor cells can be transplanted into the patient's brain.
Baron1
in
Cure Parkinson's
1 year ago
How to wean off of ropinirole and find a good doctor.
He just start going to a new one and he wants to put my husband on another
dopamine
agonist - rotigotine and unfortunately due to his stage four kidney disease, he cannot take large doses of gabapentin. He tried 600 mg for his kidneys 10 years ago and I didn’t do anything to help him.
He just start going to a new one and he wants to put my husband on another
dopamine
agonist - rotigotine and unfortunately due to his stage four kidney disease, he cannot take large doses of gabapentin. He tried 600 mg for his kidneys 10 years ago and I didn’t do anything to help him.
Sandalsforever
in
Restless Legs Syndrome
1 year ago
The Relationship Between Dopamine and Melatonin. Bronowski Institute
https://youtu.be/41XIrv0btWc https://bronowski.org/education/
https://youtu.be/41XIrv0btWc https://bronowski.org/education/
Thal
in
Cure Parkinson's
1 year ago
Mayo dopamine agonists withdrawal procedure
"Discontinuation of
dopamine
agonists because of severe augmentation or other adverse effects and substitution of a drug of a different class (such as an alpha2-delta ligand) can be achieved in 2 ways.
"Discontinuation of
dopamine
agonists because of severe augmentation or other adverse effects and substitution of a drug of a different class (such as an alpha2-delta ligand) can be achieved in 2 ways.
rls-ottawa
in
Restless Legs Syndrome
1 year ago
Hypersexuality and impulse control disorders (ICD)
The
dopamine
agonist implicated in these issues is Neupro (10mg), and we've encountered difficulties in tapering it down. Any insights or shared experiences would be greatly appreciated.
The
dopamine
agonist implicated in these issues is Neupro (10mg), and we've encountered difficulties in tapering it down. Any insights or shared experiences would be greatly appreciated.
Out_let
in
Cure Parkinson's
3 months ago
Parkinson's linked to higher levels of pheomelanin in brain: Could it be a biomarker or treatment target?
In a recent study published in Progress in Neurobiology, researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin, as well as pheomelanin markers associated with L-3,4-dihydroxyphenylalanine (DOPA) and
dopamine
, than healthy controls
In a recent study published in Progress in Neurobiology, researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin, as well as pheomelanin markers associated with L-3,4-dihydroxyphenylalanine (DOPA) and
dopamine
, than healthy controls
Hidden
in
Cure Parkinson's
1 year ago
Magnesium and dopamine
Maybe someone can help explain the effect of magnesium on
dopamine
levels.I thought a
dopamine
agonist was helpful in calming rls. Magnesium is an antagonist so decreases
dopamine
levels, yet is touted as effective in controlling rls. Don't know if I'm making any sense here.
Maybe someone can help explain the effect of magnesium on
dopamine
levels.I thought a
dopamine
agonist was helpful in calming rls. Magnesium is an antagonist so decreases
dopamine
levels, yet is touted as effective in controlling rls. Don't know if I'm making any sense here.
rmbroadh
in
Restless Legs Syndrome
1 year ago
My Story Up To Now
Duluxomine finally helped depression, and has worked on low dosage for all these years (helps with
dopamine
reuptake). When I've tried to go off, depression returns, so it seems i need some sort of low dose antidepressant. Hoping trying Wellbutrin (bupropion) will help, if my doctor approves.
Duluxomine finally helped depression, and has worked on low dosage for all these years (helps with
dopamine
reuptake). When I've tried to go off, depression returns, so it seems i need some sort of low dose antidepressant. Hoping trying Wellbutrin (bupropion) will help, if my doctor approves.
FreeqntFlier
in
Restless Legs Syndrome
1 year ago
I need help now
Obviously, all my Serotonin or
Dopamine
is totally zapped, because I have no emotions other than bad. I've had many years to deal with this and have tried everything to talk myself out of the way I feel, get up and do stuff, but I can't. I can't. Plain and simple.
Obviously, all my Serotonin or
Dopamine
is totally zapped, because I have no emotions other than bad. I've had many years to deal with this and have tried everything to talk myself out of the way I feel, get up and do stuff, but I can't. I can't. Plain and simple.
WriterG
in
CHADD's Adult ADHD Support
1 year ago
Zhittya the drug treatment that should address the root causes of the disease and not just the symptoms.
Recent research proposes that microvascular disorder hinders the blood flow to
dopamine
-producing neurons, thereby causing Parkinson's Disease.
Recent research proposes that microvascular disorder hinders the blood flow to
dopamine
-producing neurons, thereby causing Parkinson's Disease.
Bianhua
in
Cure Parkinson's
8 months ago
Using L-Tyrosine with Fluoxetine (Prozac)?
After doing a bit of research it seems Fluoxetine increases serotonin levels in the brain but does absolutely nothing for
Dopamine
levels which is why I would like to take L-Tyrosine alongside it.
After doing a bit of research it seems Fluoxetine increases serotonin levels in the brain but does absolutely nothing for
Dopamine
levels which is why I would like to take L-Tyrosine alongside it.
DP199777
in
Anxiety and Depression Support
1 year ago
The role of istradefylline in the Parkinson's disease armamentarium
As a result, an up regulation of A2A receptor occurs and weakens the efficacy of istradefylline as modulator of
dopamine
effects on motor behaviour in Parkinson's disease.
As a result, an up regulation of A2A receptor occurs and weakens the efficacy of istradefylline as modulator of
dopamine
effects on motor behaviour in Parkinson's disease.
Hidden
in
Cure Parkinson's
1 year ago
Levodopa not helping
Tremor became marked about 18 months ago and he tried a
dopamine
agonist but it made him terribly sleepy so then he was put on Madopar 100/25 twice daily but he has never experienced any diminution in the tremor or improvement in handwriting after a dose and doesn't know if it's worth continuing.
Tremor became marked about 18 months ago and he tried a
dopamine
agonist but it made him terribly sleepy so then he was put on Madopar 100/25 twice daily but he has never experienced any diminution in the tremor or improvement in handwriting after a dose and doesn't know if it's worth continuing.
goldengrove
in
Cure Parkinson's
8 months ago
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