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Experiences with
Androgen deprivation therapy (ADT)
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ADT Holiday Coming To An End
After nearly 2 years of undetectable while on
ADT
holiday my 10/2 PSA result was 0.1. Today, 10/23 my PSA was .19. Seems like a rapid doubling time. Sent result to my MO. Waiting for a response.
After nearly 2 years of undetectable while on
ADT
holiday my 10/2 PSA result was 0.1. Today, 10/23 my PSA was .19. Seems like a rapid doubling time. Sent result to my MO. Waiting for a response.
6357axbz
in
Advanced Prostate Cancer
10 months ago
Creatine?
I am not yet on
ADT
(TBD), but I want to have good habits for strength training if indeed I end up going that way. He mentioned recently that he might recommend creatine to me. I did some brief research and it seems like there's some good and bad data regarding creatine.
I am not yet on
ADT
(TBD), but I want to have good habits for strength training if indeed I end up going that way. He mentioned recently that he might recommend creatine to me. I did some brief research and it seems like there's some good and bad data regarding creatine.
MakeItRainbows
in
Advanced Prostate Cancer
9 months ago
If PSA is Suppressed by Doublet ADT, Will Salvage IMRT Cause a PSA Rise?
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
103532
in
Advanced Prostate Cancer
4 months ago
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Post-ADT, does one's ability to maintain weight get better?
This is for those lucky ones whose treatment has reached the point where their PCa is not active and
ADT
has ended. Does the ability to maintain a healthy weight get better? How long after?
This is for those lucky ones whose treatment has reached the point where their PCa is not active and
ADT
has ended. Does the ability to maintain a healthy weight get better? How long after?
Derf4223
in
Advanced Prostate Cancer
10 months ago
Orgyvux(relugolix) and Zytiga(abiraterone)
Will the
ADT
side effects be the same with the addition of Zytiga, or will they become worse? Seems like the side effects would be worse, if T is driven to a lower level. Any experience on this one?
Will the
ADT
side effects be the same with the addition of Zytiga, or will they become worse? Seems like the side effects would be worse, if T is driven to a lower level. Any experience on this one?
billd50
in
Advanced Prostate Cancer
9 months ago
Proton treatment - fatigue?
He began
ADT
4 months ago, with 1 month Lupron shot, then Orgovyx. Other than having some
ADT
mild fatigue, generally later getting up in the morning, sleepiness around 3 pm, and going to bed a bit earlier, things have pretty much been the same. No hot flashes or mood swings.
He began
ADT
4 months ago, with 1 month Lupron shot, then Orgovyx. Other than having some
ADT
mild fatigue, generally later getting up in the morning, sleepiness around 3 pm, and going to bed a bit earlier, things have pretty much been the same. No hot flashes or mood swings.
quietcorner
in
Advanced Prostate Cancer
9 months ago
Thoughts on Denosumab in my case
On monthly
ADT
injections, radiation starting soon. ——————- T score interpretation according to the National Osteoporosis Foundation: T-score at or above -1.0 Normal T-score between -1.0 and -2.5 osteopenia T-score at or below -2.5 osteoporosis REGION: L-spine (L1-4): BMD (g/cm2): 1.139 g/cm2
On monthly
ADT
injections, radiation starting soon. ——————- T score interpretation according to the National Osteoporosis Foundation: T-score at or above -1.0 Normal T-score between -1.0 and -2.5 osteopenia T-score at or below -2.5 osteoporosis REGION: L-spine (L1-4): BMD (g/cm2): 1.139 g/cm2
Hope49823
in
Advanced Prostate Cancer
6 months ago
Disgusted with Healthcare
I had to call the urologist, who I originally saw, after I joined this board and knew I should be starting
ADT
, even though they hadn't two months after my scans showed Stage IV.
I had to call the urologist, who I originally saw, after I joined this board and knew I should be starting
ADT
, even though they hadn't two months after my scans showed Stage IV.
Vangogh1961
in
Advanced Prostate Cancer
3 months ago
Protecting our Manhood
From what I know,
ADT
, once it gets going, will physically affect our family jewels. Shrinkage is one of the things that is likely to happen. What is the best way to try and reduce these effects? I see that some suggest Vacuum pumps, but do they really work?
From what I know,
ADT
, once it gets going, will physically affect our family jewels. Shrinkage is one of the things that is likely to happen. What is the best way to try and reduce these effects? I see that some suggest Vacuum pumps, but do they really work?
CJ1958
in
Prostate Cancer Network
7 months ago
PSA 6 months after RT
They looked at over 10,000 patients over a period of 10 years, and found that if your 6-month PSA is 0.1, then you might need to intensify the
ADT
treatment (longer course and/or adding extra drugs).
They looked at over 10,000 patients over a period of 10 years, and found that if your 6-month PSA is 0.1, then you might need to intensify the
ADT
treatment (longer course and/or adding extra drugs).
janebob99
in
Prostate Cancer Network
7 months ago
Strong negative reaction to first Docetaxel treatment
I have responded extremely well to
ADT
with Lupron, prednisone and Zytiga. PSA from 466 to <.10 between February and May. Should I attempt to continue chemo? I am probably willing to try again with some preventative measures thrown in but cannot go through again what I experienced this week.
I have responded extremely well to
ADT
with Lupron, prednisone and Zytiga. PSA from 466 to <.10 between February and May. Should I attempt to continue chemo? I am probably willing to try again with some preventative measures thrown in but cannot go through again what I experienced this week.
4tunate1
in
Advanced Prostate Cancer
3 months ago
Starting Abiraterone and predniSONE
Cyberknife with
ADT
October 2016 to April 2017. Chapter 3: Metastatic prostate cancer in many pelvic and abdominal lymph node October 2018. PSA reached 4.48, the highest in my life, in November when
ADT
treatment with Lupron started. Metastatic cancer hormone sensitive until October 2022.
Cyberknife with
ADT
October 2016 to April 2017. Chapter 3: Metastatic prostate cancer in many pelvic and abdominal lymph node October 2018. PSA reached 4.48, the highest in my life, in November when
ADT
treatment with Lupron started. Metastatic cancer hormone sensitive until October 2022.
dac500
in
Advanced Prostate Cancer
9 months ago
QoL Tall Trees and PSA Update
si=1JiYNBYXv046Jx9F Here's the Relay for Life album, don't think that I posted it - hmmm I blame
ADT
: https://photos.app.goo.gl/qkEDdNhFKdbRba43A And the Sequoia album: https://photos.app.goo.gl/Jk2p6ybApMMpRXur7 We drove down and our Map apps wasn't connecting, we ended up at a road closed sign
si=1JiYNBYXv046Jx9F Here's the Relay for Life album, don't think that I posted it - hmmm I blame
ADT
: https://photos.app.goo.gl/qkEDdNhFKdbRba43A And the Sequoia album: https://photos.app.goo.gl/Jk2p6ybApMMpRXur7 We drove down and our Map apps wasn't connecting, we ended up at a road closed sign
dockam
in
Advanced Prostate Cancer
3 months ago
Following SOC here in BC Canada
Started with
ADT
and Docetaxel. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing and had to get targeted radiation to painful spots on ribs.
Started with
ADT
and Docetaxel. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing and had to get targeted radiation to painful spots on ribs.
Islandboy2021
in
Advanced Prostate Cancer
4 months ago
Ugg, can we talk erections
Meaning, likely by now (more than 2mths on
ADT
) my testo has dropped very very far right? 2. Why doesnt Cialis help? 3. What is my outcome?
Meaning, likely by now (more than 2mths on
ADT
) my testo has dropped very very far right? 2. Why doesnt Cialis help? 3. What is my outcome?
Yzinger
in
Advanced Prostate Cancer
11 months ago
PSA rising, rapidly
Well, it looks like my honeymoons of
ADT
are over. I was (and still am) on a tripple therapy along the lines of the ARASENS trial (Docetaxel, Lupron and NUBEQA) for about 2 years. My PSA started rising six months ago, at first slowly, but now very rapidly.
Well, it looks like my honeymoons of
ADT
are over. I was (and still am) on a tripple therapy along the lines of the ARASENS trial (Docetaxel, Lupron and NUBEQA) for about 2 years. My PSA started rising six months ago, at first slowly, but now very rapidly.
Oldie68
in
Advanced Prostate Cancer
6 months ago
My discussion with chatGPT about senescence in PC induced by radiation and chemotherapy.
Can
adt
cause senescence? A. Androgen deprivation therapy (
ADT
) primarily aims to reduce or block male hormones like testosterone that fuel prostate cancer growth. While
ADT
can significantly shrink tumors and lead to remission in many cases, it does not directly cause cellular senescence.
Can
adt
cause senescence? A. Androgen deprivation therapy (
ADT
) primarily aims to reduce or block male hormones like testosterone that fuel prostate cancer growth. While
ADT
can significantly shrink tumors and lead to remission in many cases, it does not directly cause cellular senescence.
Seasid
in
Advanced Prostate Cancer
5 days ago
Emotional lability and LT ADT
It's really not like me and the latest incident prompted me to look into
ADT
and emotional SE's. Bingo!
It's really not like me and the latest incident prompted me to look into
ADT
and emotional SE's. Bingo!
Derf4223
in
Advanced Prostate Cancer
11 months ago
Had Davinci RP w/ LNR 8 Reoccurrence in Bed, PSA Rising 0.77 CANNOT Do Radiation active Crohn Disease / Colitis, What about Cryotherapy?
Status post
ADT
, abiraterone and chemotherapy. ABDOMINOPELVIC NODES: Decreased now predominantly resolved necrotic left pelvic adenopathy for example measuring 4.3 x 3.4 cm, previously 6.0 x 4.9 cm in the left external iliac region. Multiple additional subcentimeter pelvic nodes.
Status post
ADT
, abiraterone and chemotherapy. ABDOMINOPELVIC NODES: Decreased now predominantly resolved necrotic left pelvic adenopathy for example measuring 4.3 x 3.4 cm, previously 6.0 x 4.9 cm in the left external iliac region. Multiple additional subcentimeter pelvic nodes.
Shorehousejam
in
Advanced Prostate Cancer
4 months ago
declining psa #6
There are also some studies that show ivm to reverse
adt
castrate resistance once it starts if one chooses to continue to go that route…
There are also some studies that show ivm to reverse
adt
castrate resistance once it starts if one chooses to continue to go that route…
Nfler
in
Advanced Prostate Cancer
11 months ago
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