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Experiences with
Androgen deprivation therapy (ADT)
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Still confused about PSA and Testosterone testing
I am now doing my 6 month follow up and my annual physical and no longer on
ADT
post radiation. However I noticed all four of my doctors - GP, RO, MO and urologist are not concerned about my testosterone level and seemed focused on PSA only.
I am now doing my 6 month follow up and my annual physical and no longer on
ADT
post radiation. However I noticed all four of my doctors - GP, RO, MO and urologist are not concerned about my testosterone level and seemed focused on PSA only.
Mgtd
in
Advanced Prostate Cancer
8 months ago
One month of Orgovyx completed
Just a quick update for those Brothers on, or considering
ADT
with, Orgovyx. Today I started the second month of my 6 month sentence. As of today I have had virtually no side effects. I purposely lost 8 pounds prior to going on it, and today the scale says I am down another pound.
Just a quick update for those Brothers on, or considering
ADT
with, Orgovyx. Today I started the second month of my 6 month sentence. As of today I have had virtually no side effects. I purposely lost 8 pounds prior to going on it, and today the scale says I am down another pound.
ToolBeltZia
in
Prostate Cancer Network
8 months ago
Is nmCRPC potentially curable?
I am receiving
ADT
with early chemotherapy. I was diagnosed polymetastic but now after 5.5 years I am still on Firmagon injections only and my prostate developed a CRPC.
I am receiving
ADT
with early chemotherapy. I was diagnosed polymetastic but now after 5.5 years I am still on Firmagon injections only and my prostate developed a CRPC.
Seasid
in
Advanced Prostate Cancer
8 months ago
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Androstenedione & Frailty
Gonadal andro production is inhibited by
ADT
.
Gonadal andro production is inhibited by
ADT
.
pca2004
in
Fight Prostate Cancer
9 months ago
It's Back!
Did 39 treatments off radiation and have been mostly on
ADT
for the duration except during COVID I took a break of 18 months or so. Went metastatic about 3 1/2 to 4 years ago and started Xtandi.
Did 39 treatments off radiation and have been mostly on
ADT
for the duration except during COVID I took a break of 18 months or so. Went metastatic about 3 1/2 to 4 years ago and started Xtandi.
Tjc1
in
Advanced Prostate Cancer
7 months ago
Agonists vs. antagonists (the latter not to be confused with a character in a novel!)
I know many of you on this site are beyond
ADT
, but for those who are still holding on in that space, I'd like to share my experience with the newer antagonists drugs, degarelix ( U.S. brand, Firmagon) and relugolix (U.S. brand, Orgovyx).
I know many of you on this site are beyond
ADT
, but for those who are still holding on in that space, I'd like to share my experience with the newer antagonists drugs, degarelix ( U.S. brand, Firmagon) and relugolix (U.S. brand, Orgovyx).
bluesnjazz
in
Advanced Prostate Cancer
7 months ago
Severe coronary atherosclerosis and ADT
Not taking secondary
ADT
stuff just orchiectomy but my T is very very low .1 ng per deciliter not milliliter, deciliter translates to .001 ng per milliliter
Not taking secondary
ADT
stuff just orchiectomy but my T is very very low .1 ng per deciliter not milliliter, deciliter translates to .001 ng per milliliter
spencoid2
in
Advanced Prostate Cancer
9 months ago
happy holidays …. And a quick update
Hard to say whether just
ADT
plus Nubeqa would’ve given the same result, but so far I’m grateful for the triplet therapy, including the chemo and SBRT. Embark studies and results seem to confirm intensification for situations like mine.
Hard to say whether just
ADT
plus Nubeqa would’ve given the same result, but so far I’m grateful for the triplet therapy, including the chemo and SBRT. Embark studies and results seem to confirm intensification for situations like mine.
PGDuan
in
Advanced Prostate Cancer
8 months ago
My journey thus far
I was leaning toward radiation but the 2 years of
ADT
and those side effects are really a deterrent now that I know more. I have spoken to two friends of friends who have had RALP surgery in the last 2-3 years with very positive outcomes (said they would do the same again).
I was leaning toward radiation but the 2 years of
ADT
and those side effects are really a deterrent now that I know more. I have spoken to two friends of friends who have had RALP surgery in the last 2-3 years with very positive outcomes (said they would do the same again).
CavScout
in
Advanced Prostate Cancer
7 months ago
EMBARK Study: Enzalutamide +/- ADT
It compared high risk BCR PCa treated in 3 groups: Lupron
ADT
alone. Enzalutamide plus
ADT
. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No
ADT
) was superior to
ADT
and nearly as good as the combined treatment.
It compared high risk BCR PCa treated in 3 groups: Lupron
ADT
alone. Enzalutamide plus
ADT
. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No
ADT
) was superior to
ADT
and nearly as good as the combined treatment.
MateoBeach
in
Fight Prostate Cancer
10 months ago
What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
Wouldn’t this also enhance his ability to come off the
ADT
in a couple of years as a vacation, which he desperately wants. I apologize for the redundancy in my previous posts…..this has been weighing heavily on my mind lately. Thank you all for any input you may have.
Wouldn’t this also enhance his ability to come off the
ADT
in a couple of years as a vacation, which he desperately wants. I apologize for the redundancy in my previous posts…..this has been weighing heavily on my mind lately. Thank you all for any input you may have.
103532
in
Advanced Prostate Cancer
4 months ago
Medicare Part D decision
There are some what looks like minor differences in the formularies for each plan but the second tier
ADT
drugs, Abi, Xtandt, Erleada, etc are on both plan's formularies. The primary difference between the 2 plans is the deductible and the co-pays.
There are some what looks like minor differences in the formularies for each plan but the second tier
ADT
drugs, Abi, Xtandt, Erleada, etc are on both plan's formularies. The primary difference between the 2 plans is the deductible and the co-pays.
fireandice123
in
Advanced Prostate Cancer
5 months ago
PSA of <0.1 undetectable?
I am on
ADT
, lupron and Zytiga, at Kaiser Oakland. My latest PSA came back as <0.1. My MO sent me a message with the results: "congratulations, great news, your PSA is undetectable!"
I am on
ADT
, lupron and Zytiga, at Kaiser Oakland. My latest PSA came back as <0.1. My MO sent me a message with the results: "congratulations, great news, your PSA is undetectable!"
pj1121
in
Advanced Prostate Cancer
8 months ago
Radiation treatment for gynecomastia? Anyone?
(I know that tamoxifen is also used to combat gynecomastia but I am worried about side effects of that oral medication - - on top of side effects I already get from
ADT
medication.). Thanks much for any input.
(I know that tamoxifen is also used to combat gynecomastia but I am worried about side effects of that oral medication - - on top of side effects I already get from
ADT
medication.). Thanks much for any input.
Explorer08
in
Advanced Prostate Cancer
11 months ago
Do low PSA-producing cells still rely on testosterone to grow?
If higher PSA cells are driven to near extinction by
ADT
, and if only low-PSA producing cells survive, are the latter still dependent on testosterone for survival? If not, what do they depend on to grow?
If higher PSA cells are driven to near extinction by
ADT
, and if only low-PSA producing cells survive, are the latter still dependent on testosterone for survival? If not, what do they depend on to grow?
novatimo
in
Advanced Prostate Cancer
10 months ago
Positive case studies
Here, is presented the case of a metastatic CRPC patient affected by few and oligosymptomatic bone metastases, with an exceptional and durable response after 5 years from the starting of Ra-223 therapy and a concomitant suspension of
ADT
.
Here, is presented the case of a metastatic CRPC patient affected by few and oligosymptomatic bone metastases, with an exceptional and durable response after 5 years from the starting of Ra-223 therapy and a concomitant suspension of
ADT
.
TomsD1
in
Advanced Prostate Cancer
9 days ago
QOL gone
Prostatectomy followed 8 months later with
ADT
and radiation. Mostly incontinent since. Always had overactive bladder before cancer. Urologist did cystoscope and said everything looked normal. Its been > 2 weeks and I am in constant misery.
Prostatectomy followed 8 months later with
ADT
and radiation. Mostly incontinent since. Always had overactive bladder before cancer. Urologist did cystoscope and said everything looked normal. Its been > 2 weeks and I am in constant misery.
rfgh20
in
Advanced Prostate Cancer
9 months ago
ADT and bone health
I have been on
ADT
after radical Prostatectomy for over 14 months and to date aside from the sexual libido loss I have had very little side effects. I have always been a health / exercise buff & continue to exercise everyday to maintain my mental & physical health and so far very good results.
I have been on
ADT
after radical Prostatectomy for over 14 months and to date aside from the sexual libido loss I have had very little side effects. I have always been a health / exercise buff & continue to exercise everyday to maintain my mental & physical health and so far very good results.
Stevegr
in
Advanced Prostate Cancer
10 months ago
is this what CR looks like?
Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder to
ADT
for a long time by now (since late 2015).
Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder to
ADT
for a long time by now (since late 2015).
lokibear0803
in
Advanced Prostate Cancer
3 months ago
bone mets
My dad is on 1st line
ADT
since 2021 and just started 2nd line(abiraterone) last month.
My dad is on 1st line
ADT
since 2021 and just started 2nd line(abiraterone) last month.
dnmrk
in
Advanced Prostate Cancer
10 months ago
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