I've read all your posts for going on two years now. Some of them are truly inspiring. I've never contributed until now. My wife Ingrid was diagnosed with grade IIIc 3 1/2 years ago. At that time they gave her "months". Her cancer is low grade, but her tumours are calcifying i.e. turning to bone. They are inoperable. One has strangled her bowel, and she has been fed TPN through a Hickman line for over two years now, and she has a gastrostomy tube from her stomach which empties into a bag strapped to her leg. She cannot eat anything. Chemo wise, she has had Carboplatin + Taxol (she's allergic to Taxol so only had two minutes!), ECX, Trabectedin, Caelyx, Abraxane and now just Carboplatin. She cannot take any oral medication so everything has to be IV. Her Consultant has advised against Avastin due to possible bowel perforations which could be fatal. Nothing really seems to be helping. Does anyone have a similiar experience?