Hi, Brief background. My wife diagnosed nearly 2 years ago with High Grade Serous (3c) - had normal hyster, then 6 x 3 weekly carbo/taxol but CA125 never went below 300. Had 5 months without symptoms, then two months later had 4 x weekly sessions of taxol but CA125 continued to climb. Then had 8 sessions of gem/carbo over a 6 month period which reduced CA125 down to 100 ish (lowest ever) but still 4 measurable tumours remained.
Now 3 months later symptoms back, one of the 4 tumours is growing and perhaps a 2nd one.
Onc is talking about a phase 1 trial and obviously we would try anything. HOWEVER
I understand that OLAPARIB has decent results for some, and ditto TOPOTECAN. Then someone mentioned regular maintenance chemo just to keep things where they are.
Anyone had that and if so what, why and how is it going. Also anyone had Olaparib or Topotecan
Thanks for any responses.