Hoping to get people's thoughts about my new IVF protocol as there are a lot of changes...
Background: Have done 5 rounds of IVF (3 for banking embryos, 2 with fresh transfers) all with poor results.
-->Embryo banking cycles (one clinic):
-January 2023 (menopur 150, gonal F 150); 13 eggs, 6 mature, 5 fertilized, 2 embryos frozen (4BC day 6, 3BC day 5)
- March 2020 (OCP x2 wks, m 150, gF 300): cancelled because only 3 follicles grew
-April 2023 (m 150, gF 300): 17 eggs, 15 mature, 7 fertilized, 1 embryo frozen (4CC day 6)
-May 2023 (m 150, gF 300, growth hormone, ICSI): 13 eggs, 8 mature, 5 fertilized, 1 embryo frozen (3BA day 5)
-->Cycles with fresh transfers (new clinic):
-Nov 2023 (m 75, gF 150, ICSI): 17 eggs, 8 mature, 6 fertilized, 1 early blast transferred on day 5 but failed, nothing left to freeze
-March 2024 (m 75, gF 225, ICSI, double trigger): 11 eggs, 9 mature, 9 fertilized but all started to fragment on the morning of day 3 so 2 embryos transferred on day 3 (7 cell and 8 cell) and this failed, nothing to freeze on day 5
REI didn't think it was worth doing another cycle. Just turned 34 and want 2-3 kids, though recognizing I may not even have 1. I'm moving to a city without good access to IVF so while I am between jobs, I have decided to travel to a clinic that has expertise in challenging cases. New REI is recommending a completely new protocol with: estrogen priming, microdose leupron, growth hormone, high dose menopur and gonal F, ICSI, PGT testing, only frozen transfers. She thinks I have poor egg quality. She mentioned the possibility of doing duostim to save time, which she said we will discuss in the future.
I know I could transfer the 4 untested embryos that I have but I figured now is the only opportunity I have to get care at a place that specializes in challenging cases and is known for their great lab. Plus, I think embryo transfers are easier to coordinate with my job (I'm in medicine so am in the hospital M-F and some weekends). I've been taking lots of supplements and tried acupuncture and haven't noticed a difference. If anything, things seem to have only worsened and I have a hard time believing my eggs are rapidly declining over the course of 1 year. AMH 2.1. AFC 10-12.
My questions:
1) Has anyone noticed improvements in the ability to grow blasts with estrogen priming and microdose leupron? My biggest fear is oversuppression, which I had after priming with OCPs.
2) Has anyone without DOR done duostim? I've only heard of duostim being performed for DOR, which I dont have. I like the idea because I'm limited on time. I have a few months off between jobs and would like to focus on IVF all summer.
Thank you for all of your input. I've been really struggling lately.
Starting to doubt if this is really going to happen
Low amh high fsh...feeling really low after first ivf failed & doctor doesn’t seem confident 
Need support -- newbie here
1st scan after 1 week of stims - disappointed
FET - Day 3 or Day 5 embryos
