We did ICSI 4 days ago and on day first lab reported 2 out of 3 mature eggs fertilized but now yesterday on day 3 they called me and said that you have 3 embryos developing normal!
They said 1 of the embryos did not seem to fertilized normal on day 1 but then after they realized its developing snd on day 3 all are normal and at where they should be.
I did 4 IVF so far and this is first time I sm hearing such thing from lab. Anyone had similar experience or know anything pls share.
I am afraid they did a mistake and provide me with wrong report giving false hope? I am confused as the nurse who called just told this and did not know more! Pls help!
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Bebe294
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Embryologists class normal fertilisation as 2PN 24 hours after fertilisation which means there are two circles seen inside egg (two pronuclear I think it’s called) but sometimes there can be just 1 or even 3 which isn’t ideal (especially 3). My doc said there is no chance for the 3 pronuclear eggs to normalise (although I read studies showing they did) but the 1PN has a 50/50 chance of normalising! I had both 1PN and 3PN last round (as well as 2PNs) but neither made it to day 5. 1PN almost did! Good luck!
Hmm great detail info thanks for letting me know! All I knew was 2PN is normal and asked last cycle from them but this cycle they told me only 2 fertilized. Maybe I should better implied in my question honestly didn’t know how to!So magbe that was the case as you mentioned for us maybe by not fertilizing they meant not normal but on 1st day report they said only 2 fertilized that’s why I got shocked by day 3 they were 3 embryos.
Makes sense to be surprised! I had a 3PN after 1 day (and 2 2PN) but they DID tell me that all three had fertilized. They did however consider there being any hope for the 3PN, and it was discarded before they called me with the news.
You can ask to speak to the embryologist instead of a nurse, they’ll be able to explain exactly what they are seeing & answer any of your questions. Good luck! Xx
This clinic unfortunately does not provide details and they told me any info I need to get it through my RE! Which is very hard to get in touch with! She does not even came to see me after retrieval despite the fact that on trigger day she said I would have only one viable egg if at all and I should have decided in matter of seconds if I want to proceed with ivf on that day and pay all the money inly for one egg! Then on retreival she actually retreived 4 instead of 1! Didn’t bother to talk to me about it and just left the room.The IVFs and whole infertility story is very hard to deal with and it’s heck of a pain of grains added to the salt when you have to put up with heartless bad manner doctors! But this is my 3rd and the only one so far got some good results with so I try to hang in there still long way to go!
Wow, one of my fertilized eggs had three nuclei, but when they called to give me the 24 hour report, they said that they had just thrown it away because of that abnormality. Now, reading that sometimes even those can correct, I'm none too happy about that!! Maybe this isn't totally accurate in all cases, or nor for my situation, I don't know. I am wishing the very best outcomes for all your embryos!!
Thanks very much for great wishes xoI am very sorry about your experience.
That’s why i am afraid always to sign those million consent forms bcuz I dont want them to discard the embryos without asking!
I did not know about 1 or 3PN having a chance of surviving even little before reading JPj reply, but I know for PGS test, I keep telling my DH what if they throw them away without asking us bcuz I am willing to keep them in case we need to transfer them. I am reading all those debates on PGS aneuploids are not the end of journey and may actually self correct themselves.
Oh gush how come these doctors, nurses and infertility clinic staff do not realize how difficult and heart broken are these news when they call and drop a few lines and hang up! There other day I had a long cry and arguments with my DH over one of the eggs not fertilizing and 2 days later they called and said ohhh we just did not realize the last one fertilized! At the start of the call she even told me 4 embryos are developing and it was only after my big fat shock ohh surprise that she revised and reviewed the papers again and said no sorry 3!! Which was a surprise for me as well!!
Sorry long story... I am still upset abt all happend within the last several days and probably hormones triples the senses, sorrows etc. These days . I cannot see a movie without dropping tears!
Interesting perspective, totally forgot abt it. I thought its for after fertilization though . Beacuse we were ICSI and they call the next day, I really did not expect for the report wasn’t updated, but its good it increased, it wouldv been very difficult if opposite. Today and tomortow is the longest and hardest wait. I am always frighten to answer day 5 report! Must keep myself busy avoid thinking abt it. Thanks for your reply and bringing fresh ideas💜
Hi all,I wanted to provide update in case anyone is interested.
After a very rough 7 days we had the final report as apparently all 4 eggs fertilized but ended up with one blastocyst and 2 arrested between day 3 and 5. One was early blastocyst they watch it for an extra day to day 7 but it stopped growing.
I was very disappointed as I read some clinics they do biopsy and freeze an early blastocyst not sure why this clinic did not. But still I am grateful bcuz on trigger day Dr had told me there is only 1 egg to be retrieved if any and I ended up with 4 which still gave me 1 frozen embie.
2 years ago I was 2 years younger snd had 12 potential mature egg on trigger day but ended up with 3 mature retrieved only and no blastocyst at all which was very devastating.
Anyways thought maybe it wud b helpful and inspiring for someone reading or looking for same concerns as I had.
Good luck with the blastocyst! If you need to do another cycle consider doing day 3 transfer to have more embryos and higher chances! But hopefully this one sticks and you don’t need another cycle!
Thank you dear for your great wishes. We don’t transfer we just do embryo banking. I did 4 ivfs si far and only one time frozen transfer almost three years ago which did not take.
The plan for now is to do banking only. I get even more anxious thinking about next step as my cavity is good but the size of uterus is so big already due to one adenomyoma. RE does not agree to transfer and she says even if it does stick it will miscarry and will be disaster 🥲 She keep telling me my only option is Serrogate and ghen again she says serrogates not willing to do this with few old embies so I don’t really know what we’re going to do after but for now only try to save more embryos as much as possible as I am 45 already.
The whole process is very challenging and with this age and my bulky uterus things get even more difficult but my RE keep saying all of these every single time and this makes me even more pissed off she keep mentioning my age and not talking about what she is going to do after banking is done.
On top of all these hormones, medications, money we pay for this hefty process I am very upset about this behaviour of my RE which increase my stress . I thought she will stop blaming me for my age after she saw the great result we had with my only 2 egg becoming 2 top quality embryos first cycle and now second one top embryo but she didn’t.
Right now I am overwhelmed with all happend with her and the clinic for the last cycle and try to take a short break not thinking of what I am going to do but she pushes on deciding immediately for everything and with Corona thing going on we even could not have a proper follow up with her for last retrieval on Christmas so pissed off!
Sorry to open up about all my issues I know everyone here has their own frustrations ans I tried to keep mine but just couldn’t. My story It’s long and very sad, thinking how I wasted time and money on not competent RE when I started my ivf journey almost as a 41 year old! So at least with this one we got good results however she does mini ivfs and for next one I wanna talk her to fo a conventional one as I am not really a poor responder although they just assume based on age and keep mentioning it everywhere!
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