Donor egg to blastocyst conversion

[Orangeflowers]

Hello all,

So I found out donor egg collection was today (12 collected, 9 mature) and I'm wondering about how many blastocysts I might get.

I don't know the fertilisation rate. It was poor with my own eggs (assuming due to age). My partner does have only 3% morphology but apparently that is a minor issue as we're using ICSI.

I think the average rates of egg development are as follows:

Maturity – 80% of all retrieved eggs

Actual 12 eggs collected, 9 mature = 75%

Fertilization – 80% of all mature eggs

Would be 7.2 embryos

Embryo utilization – 30-40% of fertilized eggs/total embryos

Would be 2.1 - 2.9 embryos

Hopefully we are covered by the 2 embryo guarantee with minor sperm pathology and fertilise ok.

Looks like we should hopefully get 2 blastocysts and lucky if 3. I'm thinking we might get 3 or 4 as the donor is only 24..

I'd be interested to hear other's donor egg conversion rates i.e. number of mature eggs and number of blastocysts.

Obviously everyone's different, but interested to know.

Hope everyone is doing well xx

[DianeArnold Partner Nurse Fertility Network UK]

Hi Orangeflowers. Stop looking at numbers! You have a reliable egg donor, some reliable sperm and I’m sure a perfect home, ready and waiting for a developing embryo. All exciting stuff, so I truly hope this going to be your time and all ends as it should. Diane

[Gempuddleduck]

Hiya, I’m sure Diane is right - every pot of eggs/embryos is different.

Even so, we got 14 eggs, 9 mature, 8 on day 3, 4 blastocysts on day 5 and 2 more on day 6. We had those 6 blastocysts tested and got 3 normal and one mosaic. We have a 1 year old from the first FET and I’m currently pregnant with the second. Our donor was 26 years old. Wishing you lots of luck! Xx

[Orangeflowers in reply to Gempuddleduck]

Thank you 😊 congratulations 🎉 You got great numbers. I'm not testing so I might need more than one transfer... X

[Backagain987]

We only got 4 eggs from our donor, I was a little disappointed I have to admit! But 3 of those fertilised and we got 2 day 5 blasts and 1 day 6 blast all great quality! Our first transfer resulted in our daughter who is now 10 months old! Heaps of luck xx

[Orangeflowers in reply to Backagain987]

That's amazing 🤩 Thank you for sharing. Lovely to hear you have a daughter from this x

[Kitkat10]

hi,

I had 7 frozen donor eggs and with donor sperm, I got 2 embryos x

[Orangeflowers in reply to Kitkat10]

Thank you 😊 I hope your embryos will be/ have been successful x

[Kitkat10 in reply to Orangeflowers]

🤞🤞 thank you x 20 weeks with the first transfer 🤞🤞

[Orangeflowers in reply to Kitkat10]

Amazing, congratulations 🤩x

[Kitkat10]

my donor was 23 and from what I have read, fresh eggs have better success rates than frozen so I think you will have very good numbers 🍀🍀

My last OE attempt when I was 42, gave me 6 eggs and 3 embryos which all failed. So I was quite scared when I had fewer embryos from my donor round, but it just shows how important the age/genetics are. 🍀🤞🍀🤞 xx

[Orangeflowers in reply to Kitkat10]

Thank you. My donor is 24 so I'm hoping the embryos will be really good quality and genetically normal. It is strange hearing the numbers as I was getting as high/higher myself at 42/43, but none worked. I know they don't overstimulate the donors though so numbers will be less xx

[Krystal_43]

They retrieved 10 from our donor, and we ended up with 8 day 5 blasts 🤩

[Orangeflowers in reply to Krystal_43]

Wowser that's high!! We're they all mature? It sounds like you had a super fertile donor! 🙂 Have you tried any yet? X

[Krystal_43 in reply to Orangeflowers]

I think 9 eggs were mature, and that dropped to 8 excellent quality blasts! They did something to my partners’ sperm too (Macs & icsi) as they detected something that that’d never noticed before in my OE cycles (it was a new clinic in Spain) so that may have helped. And yes, transfer 1 didn’t work out, but I’m currently 16 weeks with transfer 2. Fingers crossed you get some sticky ones. Xxx

[Orangeflowers in reply to Krystal_43]

Amazing 😍 Congratulations 🎉 It sounds like if you want any more children you'll never need another collection 🙂 x

[Yellowlove]

Hello lovely, as Diane said it’ll be different for every human, as you’ll know, but we got 5 blastocysts from 13 donor eggs. Our donor was 35. Currently 22 weeks and hoping for the best after transfer number 3. They couldn’t find any reasons as to why the first transfers didn’t work, they were ‘better’ embryos.

The lesson I have learned so far is that anything can happen, and we have to expect surprises at every step of the way!

Good luck to you xx

[Orangeflowers]

Thank you for sharing and congratulations 🎉 That's a lot of blastocysts as your donor was on the upper age end 🙂

I just have a natural curiosity in knowing how others have got on. I'm prepared for anything to happen!

Wishing you the best for the rest of your pregnancy xx

[Yellowlove in reply to Orangeflowers]

Thank you so much. I was the same too when I was waiting for the results! In hindsight it was a decent number, but we still expected more and thought it was low because of her age, but the clinic kept assuring us that donors can now be up to 37….

[Batsford]

Hi Orangeflowers, our donor was about 21/22 I think and she had 11 eggs collected. We got 7 high quality blastocysts. Sadly I miscarried the first two, (probably because of my since diagnosed immune issues) and so we PGS tested the last 5 and 4 of the remaining five were genetically normal. I agree with Diane - if you haven’t got other factors at play, then you only need one. Keeping my fingers crossed for you!

[Orangeflowers in reply to Batsford]

Thank you. I hope your remaining transfer(s) stick🙏That's a great number x

[V3ra]

Our donor was 19 and I was initially a bit disappointed as the numbers were actually similar to my own egg rounds (I was 44 and 45 at the time of retrieval). Me - 12 eggs retrived, 10 fertilised, 2 made it to day 5 blasts resulting in failed transfers. Donor - 11 eggs retrieved, all fertilised, 3 day 5 blasts. We didn't test any of the donor embryos. Did fresh transfer (currently 22 weeks pregnant) and have 2 frosties on ice. I learnt its less about numbers and more about quality. Even if you only get 2 day 5 blasts, they should be much better quality. Good luck!

[Orangeflowers in reply to V3ra]

Agree, it's all about quality. Congratulations 🎉 Loving these success stories x

[puppylove73]

Hi Orangeflowers! We got 8 frozen eggs from our donor who was 27 years old. 2 developed into blastocysts, both were transferred and who are now 15 month old twins. The very best of luck to you. ❤️

[Orangeflowers in reply to puppylove73]

That's awesome. Congratulations 🎉There's so much quick success with donor eggs showing on here 😄 xx

[SKC111]

Hi ladies, I have started looking into DE and this post has been great to read. I have found a clinic abroad and they offer a few different price packages. You can pay more for guaranteed 1,2 or 3 blast per DE collection. It’s a gamble, if you pay the lowest amount with 1 guaranteed but get more you still get to keep these. I’m keen to hear from others who have been through the process, do you think one DE collection should hopefully 🤞🏼 be enough or have you needed mutiple DE collections? Thank you I’m advance x

[Orangeflowers in reply to SKC111]

I'd expect 2-3 embryos per donor collection. If transfer all from one collection - highly likely to get pregnant. I got 3 embryos. Now 23 weeks from first transfer x

[SKC111 in reply to Orangeflowers]

Thank you this is very helpful 🙏🏻

[SKC111 in reply to SKC111]

Wishing you all the best 👶🏼 🧡 xxxxx