Lining reduced after starting progesterone in FET

[Mglove]

Hi everyone,

Wondering if I could get some advice or see if anyone's had similar experiences.

I am 35yrs old. I've had 2 miscarriages both at 6 week (age 33). At 5 weeks both had slow heart rates of 80. Then a week later nothing. My AMH was found to be low. Dr advised to continue trying to conceive naturally and progesterone pessary to start day after ovulation. I didn't conceive naturally for 2 following years.

I went onto have 3 cycles ivf. It was meant to be mild ivf but they found that I was not responding to hormones hence was on moderate dose of bemfola 225. We got 4 embryos from 3 cycles and the plan was the go ahead with FET.

I started oestrogen tablets. On day 9 uterine lining was at 6mm hence oestrogen tabs increased to 8mg a day. On day 14 the lining was 7.6mm and all set for day 0 to start. The day prior to starting day 0 I had cramps and very tiny bit of spotting. I was told to start progesterone pessary, injections, prednisone and continue with oestrogen on day 16. I went in for a reassurance scan on day 17 and the doctor found that the lining had now shrunk to 5.5mm. They did not have any explanation for this. They said maybe the lining thickens as it leutenises with progesterone but surely that goes against why they give progesterone in the first place. My FET cycle was cancelled with a plan to start again after next months period.

Has anyone else experienced anything similar?

Thanks for reading

[Aeh711]

ShewThat has to be an emotional roller coaster. I was found to have thin uterine lining potentially

Due to having an IUD removed 5-6 months prior (that was the only reason suspected but not definitive). I did a transfer with a lining of 5.6 and am now 28 weeks pregnant. Most places won’t transfer at that lining but it worked!

[Mglove in reply to Aeh711]

Thanks so much for your reply. That's made me feel so much better.congrats on your pregnancy!!! Wishing you the best of luck

[Sea_tan]

Sorry you went through this. I don't know - maybe they gave too much progesterone - if it's their first time with you, they may not know how much to give for the body to respond. Wish you well in upcoming cycle....... 🙏

[Mglove in reply to Sea_tan]

Thanks Sea_tan. I'm hoping they will know more to inform next cycle xxx

[Godmother99]

It has happened to me both on medicated and natural fets. But persevered with a natural fet this month and lining got to 9mm and after ovulation shrunk a little to 8mm but still transferred a couple of days ago and in my 2ww wait now. So hope you and yours dr can come up with another plan for next month. Good luck x

[Mglove in reply to Godmother99]

Thanks Godmother99. Wishing you best of luck for 2ww xxx