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new immune therapy phase 1-2 trial: targeting NK cells
The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc
The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc
Maxone73
in
Advanced Prostate Cancer
4 months ago
biologic therapy blood tests to start Adalimumab
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? š³
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? š³
Bucket13
in
Crohn's and Colitis Support
11 months ago
biologic therapy
I have been on methotrexate for 20 years for RA. I started at 10 mg. Went to 15mg fairly promptly and then 20mg last year. In general I had no side effects and good quality of life. Recently I started to have a lot of flares and my rheumatologist has recommended a biologic. He said I could try upping
I have been on methotrexate for 20 years for RA. I started at 10 mg. Went to 15mg fairly promptly and then 20mg last year. In general I had no side effects and good quality of life. Recently I started to have a lot of flares and my rheumatologist has recommended a biologic. He said I could try upping
Barrcroom
in
NRAS
1 year ago
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Change in inhalers
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
spookylou
in
Asthma Community Forum
14 days ago
No meds no symptoms
I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished
I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished
Sunshine634
in
LUPUS UK
20 days ago
Biological therapy.
I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.
I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.
pmrdec112014
in
Asthma Community Forum
23 days ago
Greater use of Benlysta, Saphnelo seen in US, EU to treat lupus
Goal to reduce long-term glucocorticoids use to prevent side effects
In both the U.S. and Europe, clinicians want to limit treatment with glucocorticoids ā steroid hormones whose long-term use for autoimmune diseases is tied to serious side effects ā among people with moderate to severe lupus
Goal to reduce long-term glucocorticoids use to prevent side effects
In both the U.S. and Europe, clinicians want to limit treatment with glucocorticoids ā steroid hormones whose long-term use for autoimmune diseases is tied to serious side effects ā among people with moderate to severe lupus
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
7 months ago
Biologic therapies
I am interested to know if anyone found the injection painful? My first was in the thigh and I am wondering if next time to try the arm or stomach area? Or am I just being a big baby?! š«£
I am interested to know if anyone found the injection painful? My first was in the thigh and I am wondering if next time to try the arm or stomach area? Or am I just being a big baby?! š«£
Headoverheels
in
Asthma Community Forum
9 months ago
Shingrix vaccine for immunosuppressed people aged 50+
for autoimmune disease, such as JAK inhibitors or
biologic
immune modulators including āB-cell targeted therapies (including rituximab but for which a 6 month period should be considered immunosuppressive), monoclonal tumor necrosis factor inhibitors (TNFi), T-cell co-stimulation modulators, soluble
for autoimmune disease, such as JAK inhibitors or
biologic
immune modulators including āB-cell targeted therapies (including rituximab but for which a 6 month period should be considered immunosuppressive), monoclonal tumor necrosis factor inhibitors (TNFi), T-cell co-stimulation modulators, soluble
Sharitone
in
PMRGCAuk
6 months ago
Recurrence
I know with over OVCA (or any cancer), everyone hopes for āone and doneā, but life sometimes doesnāt work out that way. I have had a number of reoccurrences but want to share that so far Iāve been knocking them back with various treatments, whether it be chemo, radiation, targeted therapy, immunotherapy
I know with over OVCA (or any cancer), everyone hopes for āone and doneā, but life sometimes doesnāt work out that way. I have had a number of reoccurrences but want to share that so far Iāve been knocking them back with various treatments, whether it be chemo, radiation, targeted therapy, immunotherapy
Leniko
in
My Ovacome
2 days ago
Recurrence
I know with over OVCA (or any cancer), everyone hopes for āone and doneā, but life sometimes doesnāt work out that way. I have had a number of reoccurrences but want to share that so far Iāve been knocking them back with various treatments, whether it be chemo, radiation, targeted therapy, immunotherapy
I know with over OVCA (or any cancer), everyone hopes for āone and doneā, but life sometimes doesnāt work out that way. I have had a number of reoccurrences but want to share that so far Iāve been knocking them back with various treatments, whether it be chemo, radiation, targeted therapy, immunotherapy
Leniko
in
My Ovacome
2 days ago
EMBARK Trial: Combination-therapy is better.
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
janebob99
in
Prostate Cancer Network
4 days ago
Nice to be here
I have just been diagnosed with severe chronic pancreatitis. I am really scared, even though I've had bad symptoms for some time. I'm on enzyme therapy and recently had to increase the dose. Would like to talk to people that have had experience with this. Thank you and I look forward to meeting you
I have just been diagnosed with severe chronic pancreatitis. I am really scared, even though I've had bad symptoms for some time. I'm on enzyme therapy and recently had to increase the dose. Would like to talk to people that have had experience with this. Thank you and I look forward to meeting you
Corinne777
in
Couch to 5K
5 days ago
Speech production technology
Has anyone tried speech production technology, such as Stephen Hawking used, for PSP patients? Was it successful or not? Our speech therapist is asking us to consider it since we cannot understand my husband any more. Thanks
Has anyone tried speech production technology, such as Stephen Hawking used, for PSP patients? Was it successful or not? Our speech therapist is asking us to consider it since we cannot understand my husband any more. Thanks
TourEiffel
in
PSP Association
5 days ago
NDT vs T4 T3 combination therapy
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
helloworl
in
Thyroid UK
7 days ago
Bayer and AskBio report data from Parkinsonās disease therapy trial
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinsonās and MSA Scientific chair Krystof Bankiewicz said: āThese early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinsonās and MSA Scientific chair Krystof Bankiewicz said: āThese early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
Farooqji
in
Cure Parkinson's
8 days ago
CRISPR 13 (what? you thought I abandoned CRISPR?): very promising proof of concept - Targeting HOXB13 in mPCa by CRISPR/Cas13d- nanoparticle
And people thought it was undruggable....they have already filed for a patent š² Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
And people thought it was undruggable....they have already filed for a patent š² Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
Maxone73
in
Advanced Prostate Cancer
9 days ago
constipation
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now Iām passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now Iām passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
Dudders123
in
IBS Network
9 days ago
Thyroid S in UK
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
helloworl
in
Thyroid UK
9 days ago
Is it a waste?
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
EricJones
in
Anxiety and Depression Support
11 days ago
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