Experiences with

Biologic Therapy

I am now having biologic therapy for my asthma, specifically, tezspire once a month. So far I have had three injections. It's early days, I know, but my respiratory nurse has said that I should start to see an improvement in my symptoms after the third or fourth injection.

“ABD-147 is a next-generation precision radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225Ac) to solid tumors expressing DLL3, a protein found on the surface of neuroendocrine tumors, but rarely expressed on the surface of normal cells or tissues.”

In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial.

Please note this covers NHS England - and is information only at this time - https://www.gov.uk/government/publications/departmental-minute-on-the-covid-19-spring-2025-vaccination-programme/departmental-minute-from-the-department-of-health-and-social-care-notification-of-contingent-liability-covid-

Hi I was diagnosed with mixed connective tissue disease in 2022 after years of struggling. I was started with hydroxychloroquine but struggled to tolerate it. My symptoms align more with rheumatoid arthritis. I started with my latest flare in August 2024. Just doesn't seem to be getting better. I

Hi PMR ProI am not sure what to do! I have been diagnosed 10 years this week of PMR. I managed to get to 2 mgs of pred until 2 weeks ago when I had a huge flare , so did the add 5 mgs routine, and took 7mgs with good effect for two weeks till Tuesday when I reduced to 6. The symptoms are now all coming

I've been advised to start this biological therapy soon. I have tried many types of tablets and found them to be unsuitable for various reasons. My Consultant has stated that my Rheumatoid Arthritis is active and I should start the Rituximab soon. I am worried about it as I was previously advised not

Hi all, It’s been along time since I posted, I do read a lot of post which I find useful, but rarely have the time to post! I am currently off work due to change in meds again! I am currently on leflunamide as became intolerant to mtx it’s has been alot better, although swapping was a nightmare waiting

I just wanted to see if there was anyone out there similar to me and to see if anything worked. I'll try and briefly explain.... 4 years I've had it... Deep burning pain in my left bum cheek (si joint area) and throbbing burning all down my left side/leg. Basically sciatica. I can't sleep on my left

Hi It has been a long time since I have posted anything as have been severely ill with my asthma for the past two and a half years so that has taken all my time.To cut a long story short I am now on biological therapy which has so far changed my life!. Anyway I am now doing the dead slow method or whatever

The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc

”Orum has granted Vertex rights to conduct research using its TPD² approach to developing degrader-antibody conjugates (DACs), next-generation versions of antibody-drug conjugates (ADCs) which use antibodies to precisely deliver small molecule targeted protein degrader payloads to cancer cells and other

Hey All I hope everyone is well. This is my first time posting and I’m really hopeful someone will be able to advise me. I was diagnosed with lupus in Feb after just over 2 years of struggling with symptoms. Initially I was put on prednisolone and hydroxychloroquine until my bloods came back. My bloods

I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm

I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished

I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.

Hello and good morning I decided to start combination therapy today I just don't know when I should take T3? I wanted to know your friends' opinions on this Thank you

I am so overwhelmed with the response to my post and would love to say THANKYOU to ALL who have posted and who may post in the future. So people i have been on the PR and done this for 7wks and 12 sessions it was great got me motivated and educated regarding lung issues. It did help but i felt a bit

JH has a special assay. Not available to the public. Predicting Efficacy of Bipolar Androgen Therapy (BAT) in Prostate Cancer Key Predictive Biomarkers and Mechanisms Based on recent clinical trials and mechanistic studies, the following factors predict BAT efficacy: Biomarker/Mechanism Predictive

Hi everybody, I was recommended this book in a group therapy session last week - Embracing the Fear by Judith Bemis & AMR Barrada. It's a quick read and I found it to be super helpful for anyone living with anxiety/panic attacks: https://www.barnesandnoble.com/w/embracing-the-fear-judith-bemis/1102966772