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after being fast tracked ABD-147 was designed orphan drug for the Treatment of Neuroendocrine Carcinoma (prostate included)
“ABD-147 is a next-generation precision radiopharmaceutical
biologic
therapy
designed to deliver Actinium-225 (225Ac) to solid tumors expressing DLL3, a protein found on the surface of neuroendocrine tumors, but rarely expressed on the surface of normal cells or tissues.”
“ABD-147 is a next-generation precision radiopharmaceutical
biologic
therapy
designed to deliver Actinium-225 (225Ac) to solid tumors expressing DLL3, a protein found on the surface of neuroendocrine tumors, but rarely expressed on the surface of normal cells or tissues.”
Maxone73
in
Advanced Prostate Cancer
13 days ago
InkMune clinical trial goes on: second cohort is being treated
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial.
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial.
Maxone73
in
Advanced Prostate Cancer
4 months ago
new immune therapy phase 1-2 trial: targeting NK cells
The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc
The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc
Maxone73
in
Advanced Prostate Cancer
9 months ago
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Will Biological Therapy drugs work for me?!
I just wanted to see if there was anyone out there similar to me and to see if anything worked. I'll try and briefly explain.... 4 years I've had it... Deep burning pain in my left bum cheek (si joint area) and throbbing burning all down my left side/leg. Basically sciatica. I can't sleep on my left
I just wanted to see if there was anyone out there similar to me and to see if anything worked. I'll try and briefly explain.... 4 years I've had it... Deep burning pain in my left bum cheek (si joint area) and throbbing burning all down my left side/leg. Basically sciatica. I can't sleep on my left
BusyMumOfBoys
in
Pain Concern
18 days ago
Never been this low in 9 and a half years!
Hi It has been a long time since I have posted anything as have been severely ill with my asthma for the past two and a half years so that has taken all my time.To cut a long story short I am now on biological therapy which has so far changed my life!. Anyway I am now doing the dead slow method or whatever
Hi It has been a long time since I have posted anything as have been severely ill with my asthma for the past two and a half years so that has taken all my time.To cut a long story short I am now on biological therapy which has so far changed my life!. Anyway I am now doing the dead slow method or whatever
pmrdec112014
in
PMRGCAuk
1 month ago
a new platform for ADC development….no sorry, it’s DAC this time! not PCa related but hopefully soon
”Orum has granted Vertex rights to conduct research using its TPD² approach to developing degrader-antibody conjugates (DACs), next-generation versions of antibody-drug conjugates (ADCs) which use antibodies to precisely deliver small molecule targeted protein degrader payloads to cancer cells and other
”Orum has granted Vertex rights to conduct research using its TPD² approach to developing degrader-antibody conjugates (DACs), next-generation versions of antibody-drug conjugates (ADCs) which use antibodies to precisely deliver small molecule targeted protein degrader payloads to cancer cells and other
Maxone73
in
Advanced Prostate Cancer
2 months ago
Biological Therapy - too soon?
Hey All I hope everyone is well. This is my first time posting and I’m really hopeful someone will be able to advise me. I was diagnosed with lupus in Feb after just over 2 years of struggling with symptoms. Initially I was put on prednisolone and hydroxychloroquine until my bloods came back. My bloods
Hey All I hope everyone is well. This is my first time posting and I’m really hopeful someone will be able to advise me. I was diagnosed with lupus in Feb after just over 2 years of struggling with symptoms. Initially I was put on prednisolone and hydroxychloroquine until my bloods came back. My bloods
EeBeee
in
LUPUS UK
2 months ago
Change in inhalers
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
spookylou
in
Asthma Community Forum
5 months ago
No meds no symptoms
I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished
I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished
Sunshine634
in
LUPUS UK
6 months ago
Biological therapy.
I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.
I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.
pmrdec112014
in
Asthma Community Forum
6 months ago
biologic therapy blood tests to start Adalimumab
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? 😳
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? 😳
Bucket13
in
Crohn's and Colitis Support
1 year ago
Greater use of Benlysta, Saphnelo seen in US, EU to treat lupus
Goal to reduce long-term glucocorticoids use to prevent side effects
In both the U.S. and Europe, clinicians want to limit treatment with glucocorticoids — steroid hormones whose long-term use for autoimmune diseases is tied to serious side effects — among people with moderate to severe lupus
Goal to reduce long-term glucocorticoids use to prevent side effects
In both the U.S. and Europe, clinicians want to limit treatment with glucocorticoids — steroid hormones whose long-term use for autoimmune diseases is tied to serious side effects — among people with moderate to severe lupus
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
11 months ago
biologic therapy
I have been on methotrexate for 20 years for RA. I started at 10 mg. Went to 15mg fairly promptly and then 20mg last year. In general I had no side effects and good quality of life. Recently I started to have a lot of flares and my rheumatologist has recommended a biologic. He said I could try upping
I have been on methotrexate for 20 years for RA. I started at 10 mg. Went to 15mg fairly promptly and then 20mg last year. In general I had no side effects and good quality of life. Recently I started to have a lot of flares and my rheumatologist has recommended a biologic. He said I could try upping
Barrcroom
in
NRAS
1 year ago
consultant wants to reduce inhaler
I know it's likely I will need steroids again in the future without some type of
biologic
therapy
. My eosinophil count has been a bit raised during flare-ups (0.3) but not enough it seems to warrant any further therapy.
I know it's likely I will need steroids again in the future without some type of
biologic
therapy
. My eosinophil count has been a bit raised during flare-ups (0.3) but not enough it seems to warrant any further therapy.
ccccc
in
Asthma Community Forum
2 months ago
Biologic therapies
I am interested to know if anyone found the injection painful? My first was in the thigh and I am wondering if next time to try the arm or stomach area? Or am I just being a big baby?! 🫣
I am interested to know if anyone found the injection painful? My first was in the thigh and I am wondering if next time to try the arm or stomach area? Or am I just being a big baby?! 🫣
Headoverheels
in
Asthma Community Forum
1 year ago
Treatment Preferences in Patients with Hypothyroidism: an Analysis of Eleven Randomized Controlled Trials
I have only read this abstract - once, and very quickly - hence no real comments. But patients preferring combination treatment is hardly a surprise. We'd probably prefer out own nicely working thyroid - which would be producing T4 and T3. Wouldn't it? [i]Treatment Preferences in Patients with Hypothyroidism
I have only read this abstract - once, and very quickly - hence no real comments. But patients preferring combination treatment is hardly a surprise. We'd probably prefer out own nicely working thyroid - which would be producing T4 and T3. Wouldn't it? [i]Treatment Preferences in Patients with Hypothyroidism
helvella
Thyroid UK
in
Thyroid UK
7 hours ago
Dr. Selection for Proton Therapy
Hi all, I've been diagnosed with advanced prostate cancer. Gleason 9 with metastatic to the right seminal vessel and one lymph node. Currently getting registered at Loma Linda and also the Proton Center at San Diego. Dr. Rossi just went on vacation for a month, so he's unfortunately a no-go, and I'm
Hi all, I've been diagnosed with advanced prostate cancer. Gleason 9 with metastatic to the right seminal vessel and one lymph node. Currently getting registered at Loma Linda and also the Proton Center at San Diego. Dr. Rossi just went on vacation for a month, so he's unfortunately a no-go, and I'm
Garfield-_1234
in
Advanced Prostate Cancer
6 days ago
Very painful steroid injection
Hello! I wanted some advice or to hear there’s light at the end of this miserable tunnel I have been getting steroid injections for the last 10 years into my toes and my thumbs. I have just had to move house and the packing put my hands into a lot of pain. So the doctor put steroids into my thumbs and
Hello! I wanted some advice or to hear there’s light at the end of this miserable tunnel I have been getting steroid injections for the last 10 years into my toes and my thumbs. I have just had to move house and the packing put my hands into a lot of pain. So the doctor put steroids into my thumbs and
Tonkie
in
NRAS
8 days ago
Digoxin with Bisoprol
Hi all, My dad is in persistent AFib. He was started on Digoxin 125mg after diagnosis of heart failure. He saw an EP and was additionally prescribed Bisoprol 2.5mg last week. Today is day 6 of him taking Bisoprol. He has been feeling slightly breathless from just walking around in his apartment/flat
Hi all, My dad is in persistent AFib. He was started on Digoxin 125mg after diagnosis of heart failure. He saw an EP and was additionally prescribed Bisoprol 2.5mg last week. Today is day 6 of him taking Bisoprol. He has been feeling slightly breathless from just walking around in his apartment/flat
priya_uk
in
Atrial Fibrillation Support
8 days ago
hdr brachytherapy or proton for salvage tx
MSK RO (Gorovets) recommends proton sbrt due to my preexisting urinary issues….hdr brachytherapy logistically is a LOT easier for me…..wondering if anyone here has any experience or opinions on this topic…..with all the hype about proton therapy and few studies to back it up definitively I’d hate to
MSK RO (Gorovets) recommends proton sbrt due to my preexisting urinary issues….hdr brachytherapy logistically is a LOT easier for me…..wondering if anyone here has any experience or opinions on this topic…..with all the hype about proton therapy and few studies to back it up definitively I’d hate to
Tommyj2
in
Advanced Prostate Cancer
8 days ago
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