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NDT vs T4 T3 combination therapy
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
helloworl
in
Thyroid UK
15 days ago
Bayer and AskBio report data from Parkinson’s disease therapy trial
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinson’s and MSA Scientific chair Krystof Bankiewicz said: “These early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinson’s and MSA Scientific chair Krystof Bankiewicz said: “These early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
Farooqji
in
Cure Parkinson's
16 days ago
CRISPR 13 (what? you thought I abandoned CRISPR?): very promising proof of concept - Targeting HOXB13 in mPCa by CRISPR/Cas13d- nanoparticle
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
Maxone73
in
Advanced Prostate Cancer
16 days ago
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constipation
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now I’m passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now I’m passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
Dudders123
in
IBS Network
17 days ago
Thyroid S in UK
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
helloworl
in
Thyroid UK
17 days ago
Is it a waste?
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
EricJones
in
Anxiety and Depression Support
18 days ago
Major depressive disorder
I was with my ex for 36 years before I foiled for a divorce. We remained close . December 2023 was 1 year for our divorce. He had at least 3 affairs that I proved, I believe he had at least 3 or 4 more that I couldn’t prove. He asked me to move in with him February this year, I did because I thought
I was with my ex for 36 years before I foiled for a divorce. We remained close . December 2023 was 1 year for our divorce. He had at least 3 affairs that I proved, I believe he had at least 3 or 4 more that I couldn’t prove. He asked me to move in with him February this year, I did because I thought
raisin44
in
Anxiety and Depression Support
19 days ago
combination therapy for ADHD
Does anyone have experience using combination therapy of a stimulant plus a non-stimulant? From what I understand, you take the stimulant in the morning and the non-stimulant in the late afternoon or evening. I recently started using Adderall ir. Having a lot of trouble in the evening and at night
Does anyone have experience using combination therapy of a stimulant plus a non-stimulant? From what I understand, you take the stimulant in the morning and the non-stimulant in the late afternoon or evening. I recently started using Adderall ir. Having a lot of trouble in the evening and at night
starsallover
in
CHADD's Adult ADHD Support
23 days ago
Excessive Sleeping
My husband was diagnosed in early 2020 with MSA. The decline was rapid - he is now on PEG for feeds, intermittent urine catheter, flatus tube for bowel movement, and a tracheotomy with ventilator on at night He has speech therapy, physiotherapy, occupational therapy that fills up his days However
My husband was diagnosed in early 2020 with MSA. The decline was rapid - he is now on PEG for feeds, intermittent urine catheter, flatus tube for bowel movement, and a tracheotomy with ventilator on at night He has speech therapy, physiotherapy, occupational therapy that fills up his days However
binnyrox
in
Multiple System Atrophy Trust
25 days ago
Protein discovery could help solve prostate cancer drug resistance Date:January 22, 2024 Source:Washington State University
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
MsHope
in
Advanced Prostate Cancer
25 days ago
Feeling paranoid
I'm at group therapy and I'm feeling really paranoid right now. More than usual. I'm afraid that someone will notice my paranoia and shame me for it ...thoughts?
I'm at group therapy and I'm feeling really paranoid right now. More than usual. I'm afraid that someone will notice my paranoia and shame me for it ...thoughts?
EricJones
in
Anxiety and Depression Support
25 days ago
Oxygen therapy
I am helping to look after my 88 year old sister at present. She has been prescribed ambulatory oxygen therapy following a diagnosis of pulmonary hypertension, I think related to her Protein S Deficiency. She is frail and even the small oxygen cylinders are heavy and difficult for her to use but oxygen
I am helping to look after my 88 year old sister at present. She has been prescribed ambulatory oxygen therapy following a diagnosis of pulmonary hypertension, I think related to her Protein S Deficiency. She is frail and even the small oxygen cylinders are heavy and difficult for her to use but oxygen
mozart27
in
Lung Conditions Community Forum
27 days ago
thanks you brilliant freinds!
thanks for all your replies means the world.as usual im picking my battles should i be proud to say im getting good at it?no way,but there you have it.sean and myself have hilarious exchanges with my "speech therapy"sessions.when i visited yesterday had my fur teddy coat.sean insisted on wearing...you
thanks for all your replies means the world.as usual im picking my battles should i be proud to say im getting good at it?no way,but there you have it.sean and myself have hilarious exchanges with my "speech therapy"sessions.when i visited yesterday had my fur teddy coat.sean insisted on wearing...you
Dogsabighelp
in
Headway
27 days ago
Home Oxygen Therapy
I don't recall seeing this mentioned on here but was wondering if anyone had experiences of being discharged home with Oxygen after an ICU stay. I'm a month out of hospital (after a total stay of 8 months). I was discharged with a CPAP machine for OSA and prescribed 1l of oxygen at night whilst in the
I don't recall seeing this mentioned on here but was wondering if anyone had experiences of being discharged home with Oxygen after an ICU stay. I'm a month out of hospital (after a total stay of 8 months). I was discharged with a CPAP machine for OSA and prescribed 1l of oxygen at night whilst in the
CCXLI
in
ICUsteps
28 days ago
Shingrix vaccine for immunosuppressed people aged 50+
for autoimmune disease, such as JAK inhibitors or
biologic
immune modulators including ●B-cell targeted therapies (including rituximab but for which a 6 month period should be considered immunosuppressive), monoclonal tumor necrosis factor inhibitors (TNFi), T-cell co-stimulation modulators, soluble
for autoimmune disease, such as JAK inhibitors or
biologic
immune modulators including ●B-cell targeted therapies (including rituximab but for which a 6 month period should be considered immunosuppressive), monoclonal tumor necrosis factor inhibitors (TNFi), T-cell co-stimulation modulators, soluble
Sharitone
in
PMRGCAuk
6 months ago
Occupational Therapy
Hi everyone, my 11 year old was diagnosed with ADHD six years ago. I am just wondering for those who are having occupational therapy as part of an accommodation - it what ways has it been helpful or if it has been helpful? Just trying to get a sense of how occupational therapy might fit in.
Hi everyone, my 11 year old was diagnosed with ADHD six years ago. I am just wondering for those who are having occupational therapy as part of an accommodation - it what ways has it been helpful or if it has been helpful? Just trying to get a sense of how occupational therapy might fit in.
Uptowngirl12121
in
CHADD's ADHD Parents Together
1 month ago
Update in sustained release T3 and new paper
The recent review of treatment for hypothyroidism recommended further research to look at combination therapy. A group in Iran have done the following trial looking at sustained release combination T4/T3. Fascinating…… it suggests that daily sustained release capsules can deliver a stable T3 level over
The recent review of treatment for hypothyroidism recommended further research to look at combination therapy. A group in Iran have done the following trial looking at sustained release combination T4/T3. Fascinating…… it suggests that daily sustained release capsules can deliver a stable T3 level over
Mollyfan
in
Thyroid UK
1 month ago
Photopharmics kickstarts phototherapy trial for Parkinson’s disease
The US Food and Drug Administration (FDA)-approved device targets photoreceptors in the eye responsible for circadian signalling. Research has shown that Parkinson’s disease can damage the retina and impact the circadian system leading to symptoms such as trouble sleeping, cognition, depression, and
The US Food and Drug Administration (FDA)-approved device targets photoreceptors in the eye responsible for circadian signalling. Research has shown that Parkinson’s disease can damage the retina and impact the circadian system leading to symptoms such as trouble sleeping, cognition, depression, and
Farooqji
in
Cure Parkinson's
1 month ago
apathy
hi This is my first post, my husband 79 was diagnosed with PSP 18 months ago. My biggest frustration and upset is his apathy and lack of communication. We can have good and bad days and at hospital appointments he has proved he is able to communicate. It is just heartbreaking that he has no will or
hi This is my first post, my husband 79 was diagnosed with PSP 18 months ago. My biggest frustration and upset is his apathy and lack of communication. We can have good and bad days and at hospital appointments he has proved he is able to communicate. It is just heartbreaking that he has no will or
Tulipstaffie
in
PSP Association
1 month ago
Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Graham49
in
Advanced Prostate Cancer
1 month ago
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