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What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
103532
in
Advanced Prostate Cancer
18 days ago
Declining psa #9
Gm folks, hope all are having a wonderful New Year. I’m following up n giving results on using ivermectin, cbd oil, turmeric Vit b3,6,12 Vit c And zinc solely after eliminating ADT after 7 months, post Rp n rad… Psa dropped another .29 points to .66 down from .95 n psa was hovering 7 when I first got
Gm folks, hope all are having a wonderful New Year. I’m following up n giving results on using ivermectin, cbd oil, turmeric Vit b3,6,12 Vit c And zinc solely after eliminating ADT after 7 months, post Rp n rad… Psa dropped another .29 points to .66 down from .95 n psa was hovering 7 when I first got
Nfler
in
Advanced Prostate Cancer
4 months ago
Anyone tried adrenal supplements? Any feedback please?
Currently looking at adrenal supplements saw from an old post on here a product recommendation and used by a Dr P but this has been discontinued now and the closest product is this one. Thorne Advanced Adrenal Cortex. Any feedback on these supplements or similar support please and what supplements
Currently looking at adrenal supplements saw from an old post on here a product recommendation and used by a Dr P but this has been discontinued now and the closest product is this one. Thorne Advanced Adrenal Cortex. Any feedback on these supplements or similar support please and what supplements
Fizzwhizz
in
Thyroid UK
4 months ago
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Stratification test for ADT effectiveness
As someone who has had the awful experience of ADT side effects, I give this tool a standing ovation: https://artera.ai/arteraai-prostate-cancer-test Just approved for Medicare coverage, and just a matter of time before California and New York join the other 48 states in approving it.
As someone who has had the awful experience of ADT side effects, I give this tool a standing ovation: https://artera.ai/arteraai-prostate-cancer-test Just approved for Medicare coverage, and just a matter of time before California and New York join the other 48 states in approving it.
ron_bucher
in
Advanced Prostate Cancer
4 months ago
SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
4 months ago
Has anyone taken a non-medication route and seen an improvement in their osteoporosis through only supplements/diet/exercise?
Hello, I have osteoporosis and been advised to take medication - either HRT or Alendronate. However, I as an alternative wondered whether anyone who is not on medication has seen an improvement in their osteoporosis through only supplements/diet/exercise?
Hello, I have osteoporosis and been advised to take medication - either HRT or Alendronate. However, I as an alternative wondered whether anyone who is not on medication has seen an improvement in their osteoporosis through only supplements/diet/exercise?
Houseelf
in
Bone Health and Osteoporosis UK
4 months ago
What is the next step
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
old64horn
in
Advanced Prostate Cancer
4 months ago
Follow up to "My trajectory after a 'vacation' and a new metastasis," and a new question
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
Istomin
in
Advanced Prostate Cancer
4 months ago
Low appetite
Hi, undiagnosed but strongly suspect hypo possibly Hashi and gathering info/signs etc. Started supplements for folate, vit d (with k) and b complex just about to start magnesium too. On HRT including DHEA. So, my appetite has been on the wane, probably since menopause and thyroid problems began.
Hi, undiagnosed but strongly suspect hypo possibly Hashi and gathering info/signs etc. Started supplements for folate, vit d (with k) and b complex just about to start magnesium too. On HRT including DHEA. So, my appetite has been on the wane, probably since menopause and thyroid problems began.
Fizzwhizz
in
Thyroid UK
4 months ago
PCNA gene attack -- for solid tumors
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Derf4223
in
Advanced Prostate Cancer
9 months ago
ASCO 2023: AI-Derived Digital Pathology Biomarker Predicts Benefit of Long-Term ADT with Radiotherapy in Localized High-Risk Prostate Cancer
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
zeitgeistxx
in
Advanced Prostate Cancer
4 months ago
Short-term vs Long-Term ADT for High Risk Men
Here's a review of a recent presentation at ASCO 2023 by Artera.ai regarding the use of Artificial Intelligence analysis of biopsy slides to predict which high-risk men do or don't benefit from short-term ADT vs long-term ADT. Their findings are summarized here: [i]"Based on these results, it appears
Here's a review of a recent presentation at ASCO 2023 by Artera.ai regarding the use of Artificial Intelligence analysis of biopsy slides to predict which high-risk men do or don't benefit from short-term ADT vs long-term ADT. Their findings are summarized here: [i]"Based on these results, it appears
janebob99
in
Prostate Cancer Network
4 months ago
Managing OAB after proton RT
Hello everyone, This 73 year old treated an unfavorable intermediate localized PCa with 28 fractions of proton radiation, completed on Dec. 15th. Completed a 4 months course of oral Orgovyx on Dec. 28th. The side effects of the ADT were hot flashes (tolerable) and loss of libido. The side effects
Hello everyone, This 73 year old treated an unfavorable intermediate localized PCa with 28 fractions of proton radiation, completed on Dec. 15th. Completed a 4 months course of oral Orgovyx on Dec. 28th. The side effects of the ADT were hot flashes (tolerable) and loss of libido. The side effects
old_reliable
in
Prostate Cancer Network
4 months ago
Will T return?
As I near the end of my 2 years of ADT (Lupron + Abi), I am curious if I should expect a return of Testosterone. I would love to regain my libido and endurance. But after 2 years, I don't know what to expect. My MO has been pretty vague about what to expect. Another issue is that I didn't have a
As I near the end of my 2 years of ADT (Lupron + Abi), I am curious if I should expect a return of Testosterone. I would love to regain my libido and endurance. But after 2 years, I don't know what to expect. My MO has been pretty vague about what to expect. Another issue is that I didn't have a
jmarsh
in
Advanced Prostate Cancer
4 months ago
What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
7 months ago
EBRT - Is it the right thing and what to expect?
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
JazzMan42
in
Advanced Prostate Cancer
30 days ago
PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
4 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
Teddy28
in
Advanced Prostate Cancer
4 months ago
A week of withdrawal from running
Well Monday last week was the week we found out how well my shoulder had healed! In the words of the consultant it’s tried to heal it’s self but it has healed! After 6months it should have unified but it hasn’t! So now we are going to try ultrasound therapy for the next 3 - 6 months to get it to heal
Well Monday last week was the week we found out how well my shoulder had healed! In the words of the consultant it’s tried to heal it’s self but it has healed! After 6months it should have unified but it hasn’t! So now we are going to try ultrasound therapy for the next 3 - 6 months to get it to heal
BGood
in
Couch to 5K
9 months ago
BONE DENSITY TEST IS BAD
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. that’s the
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. that’s the
JL1955
in
Advanced Prostate Cancer
4 months ago
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