Blood Test Results - now Overactive!: Hello again... - Thyroid UK

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Blood Test Results - now Overactive!

Clarice165 profile image
17 Replies

Hello again, I have received by blood test results back from Medichecks and the report says that I have now gone from Underactive to Overactive since I started taking Metavive in late September this year! Please see my results below:-

TSH Before - 3.64 (0.35- 4.9)

Now - 0.005 (0.27- 4.2)

FT3 Before - 15.6 (12-22)

Now - 8.1 (3.1-6.8)

FT4 Before - 4.1 (3.2 - 6.8)

Now - 24.3 (12-22)

CRP HS - 1.74

Iron - 125

Folate - 45.4

Vitamin B12 - 150

Vitamin D - 166

The Anti- bodies showed no evidence of Auto- Immune Thyroid disease.

I contacted my private Doctor and she said to reduce my Metavive dose to 4 x Metavive 2 a day as it is clear that I have been on too high a dose. I have started this in the last few days and am beginning to feel slightly better although still suffering with ongoing fatigue and my body feels heavy all the time.

I would be grateful for any help and further advice you can give me on my current situation as you were very helpful and knowledgeable last time - thank you.

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17 Replies
tattybogle profile image
tattybogle

TSH Before - 3.64 (0.35- 4.9)

Now - 0.005 (0.27- 4.2)

FT4 Before - 15.6 (12-22)

Now - 24.3 (12-22)

FT3 Before - 4.1 (3.1 - 6.8)

Now - 8.1 (3.1-6.8)

(hi , i've corrected typo's , as the fT4 / 3 results were wrong way round on your post) .

so yes both fT4 and fT3 levels are now high , so reducing dose is sensible .

'overactive' is incorrect term when someone is taking thyroid hormones , 'overmedicated' is a better description for high T4/3 levels and symptoms that are a result of the dose , (rather than a continuous excess of T4/T3 coming from the thyroid itself )

for overmedication the fix is simply to reduce the dose a bit .

Thyb profile image
Thyb in reply totattybogle

haven't heard of Metavive before. Is it prescription only or? Is it a Combination Combination ft4 and ft3 or just t3 medication please?

tattybogle profile image
tattybogle in reply toThyb

Thyb ~ it is explained in replies to this post : healthunlocked.com/thyroidu... advice-on-metavive-2-underactive-thyroid

pennyannie profile image
pennyannie

Hey there again :

So, before you started the Metavive :-

your TSH was 3.63 with a T3 @ 4.10 and a T4 @ 15.60 -

so technically, currently, not hypothyroid as the NHS do not start treatment until the TSH is over 10 on 2 separate blood tests - months apart. - if with negative thyroid antibodies

though years ago the NHS would diagnose you as hypothyroid once the TSH tipped over 3 -

and we know many symptoms start creeping in once the TSH tips over 2 :

The Metavive has worked - your TSH. T3 and T4 have all risen with hopefully some relief of symptoms but your dose needs reducing as your T3 and T4 readings are now a little high = and you experiencing symptoms of over medication.

Is the iron result - ferritin and the B12 active - or serum - please add ranges - folate and vitamin D ' look high '

If supplementing - adjust down whatever it is you are taking.

For reference I now aim to maintain ferritin at around 100 - folate around 20 - active B12 125 ( serum B12 500_++ ) and vitamin D at around 125.

Were both TPO and TgAB run ?

Over medication can be as debilitating as under medication -

now all you need to do is find your sweet spot -

let's hope this next dose adjustments ' hit the spot ' - maybe try monitoring your blood pressure, pulse and body temperature AM & PM - this might just make you aware of subtle physical facts that you can track alongside symptoms which sometimes can be confusing.

Thyb profile image
Thyb in reply topennyannie

I haven't heard of Metavive before. Is it prescription only or? Is it a Combination Combination ft4 and ft3 or just t3 medication please?

pennyannie profile image
pennyannie in reply toThyb

I can see Tatty has beaten me to it and already given you the link :

Clarice165 profile image
Clarice165 in reply topennyannie

Thanks for your reply. Yes the Iron result is Ferritin (range 30-264) and the B12 is active (range 37.5?). Yes both Antibody tests were run:

Thyroglobulin - 21.1 (0 - 115)

Thyroid Peroxidase - 27.8 (0 - 34)

I am a bit confused about your last paragraph. I have been monitoring my blood pressure and pulse so far. Can you explain about the temperature checks as not sure how these can inform me about it??

I'll be having some annual blood tests in January at the GP - should I tell them about what is going on as last time they were ZERO help??

pennyannie profile image
pennyannie in reply toClarice165

When I gave up on the NHS doctor and started self medicating I tracked myself on the physical. clinical symptoms of blood pressure, pulse and body temperature - AM & PM - just so I could try and understand my body a bit better - and that I was going in the right direction -

My pulse and blood pressure remained stable - but my temperature which was at 35.4 and ' considered low and a known hypothyroid symptom- slowly moved up as I increased my dose and now hovers around 36.6 - and my body core a little warmer.

As for your NHS doctor - you can say that you are having Private treatment for your thyroid and by then I hope you will feel more improved than now - your doctor may scoff - but s/he works to NHS guidelines and can't diagnosis and treat until you meet the criteria which leaves many patients, especially women - struggling on believing it's all in their heads !!

I see you have had help from SDragon on the Auto Immune aspects of thyroid disease and the potential stomach issues of certain food stuffs that maybe causing some issues being tolerated.

You might like to read around on the research of Dr Izabella Wentz - as many forum members find her suggestions useful - and she writes as - thyroidpharmacist.com

Clarice165 profile image
Clarice165 in reply topennyannie

Thanks very much for your help.....much appreciated 😀

Clarice165 profile image
Clarice165 in reply toClarice165

PS How long should I wait on the new Metavive dose to see if it is right for me or not? About two weeks?

SlowDragon profile image
SlowDragonAdministrator

The Anti- bodies showed no evidence of Auto- Immune Thyroid disease.

Have you tested BOTH TPO and TG thyroid antibodies

I contacted my private Doctor and she said to reduce my dose to 4 x Metavive 2 a day

How much Metavive were you taking before reducing

Clarice165 profile image
Clarice165 in reply toSlowDragon

Yes I think so - please see my reply to pennyannie. I was taking 5 x Metavive 2 before and had increased it too much too quickly!

SlowDragon profile image
SlowDragonAdministrator in reply toClarice165

yes too much too soon

Are you gluten free and dairy free diet?

Clarice165 profile image
Clarice165 in reply toSlowDragon

Yes gluten free and dairy free apart from I do have a bit of cheese! Is it a good thing that it isn't an auto immune condition??

SlowDragon profile image
SlowDragonAdministrator in reply toClarice165

Was TPO antibodies tested at any point previously

If high at any test, even if now negative, cause is still autoimmune

ever had ultrasound scan of thyroid

Have you noticed any improvement since being gluten free or dairy free

Clarice165 profile image
Clarice165 in reply toSlowDragon

No my private doctor didn't test for them. No I've had no help from the GP/nhs and no Ultrasound scan.I think the diet is helping with my digestive system and gut health.

SlowDragon profile image
SlowDragonAdministrator in reply toClarice165

and no Ultrasound scan

20% of Hashimoto's patients never have raised antibodies

healthunlocked.com/thyroidu...

Paul Robson on atrophied thyroid - especially if no TPO antibodies

paulrobinsonthyroid.com/cou...

thyroiduk.org/testing/other...

I think the diet is helping with my digestive system and gut health.

Suggests that it’s possible/likely autoimmune

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