Help with results please : Hi everyone. I have... - Thyroid UK

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Help with results please

Lottieanne profile image
14 Replies

Hi everyone. I have been lingering for a while and hope that you can help me.I have my last 3 results from medichecks.

25/01/24

Crp 75.6 (less than 3)

Ferritin 143 (30-264)

Folate serum 10.1 (more than 7)

Vit B12 active 59.7 (37.5 - 188)

Vitamin D 25.3 (50 - 250)

Tsh 9.91 (0.27 - 4.2)

FT3 3.4 (3.1 - 6.8)

FT4 18.5 (12 - 22)

Thyroglobin antibodies 330 (0 - 115)

Thyroid peroxidase antibodies 310 (0 - 34)

I noticed my Vitamin D was really low so started taking Better You D3000 +K2 spray, which made me feel brain fogged and painful bones.

Then I did another blood test

11/4/24

Crp 6.1 (less than 3)

Ferritin 71.9 (30 - 264)

Folate - sample error

Vit B12 active 39.2 (37.5-188)

Vitamin D 44.2 (50-250)

Tsh 2.57 (0.27-4.2)

Ft3 3.9 (3.1-6.8)

FT4 17.8 (12-22)

I had to stop taking the vitamin D as it was making me feel absolutely rubbish.

19/6/24

Crp 6.1 (less than 3)

Ferritin 62.1 (30-264)

Folate 8.4 (more than 7)

Vitamin B12 active 77.1 (37.5-188)

Vitamin D 48.7 (50-250)

Tsh 8.03 (0.27-4.2)

Ft3 4 (3.1-6.8)

FT4 19.1 (12-22)

I still feel rubbish and no energy. My get up and go has got up and gone. If I do anything I get terrible back ache and feel drained. I also have terrible reflux, hair wiry and falling out. No body hair on arms and legs,bloated,dry skin and throat tightening.

I can't increase my levothyroxine as it makes me feel even more undermedicated with swelling face and abdomen. I did try increasing my dose before but ended up with T4 of 28.

My dose is 100/125 at the moment.

Thank you for any advice you can give.

Anne

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14 Replies
SlowDragon profile image
SlowDragonAdministrator

welcome to the forum

Your results show the cause of your hypothyroidism is autoimmune thyroid disease (hashimoto’s)

Like many people with Hashimoto’s you have poor conversion of Ft4 to Ft3

First step is to improve all your vitamins

Folate and vitamin D are both far too low

Ferritin result is unreliable as your CRP is high

CRP is test for inflammation

High CRP tends to falsely increase ferritin levels

So you need FULL iron panel test

Test early morning, only water to drink between waking and test. Avoid high iron rich dinner night before test

If on iron supplements stop these 5-7 days before testing

Medichecks iron panel test

medichecks.com/products/iro...

Lottieanne profile image
Lottieanne in reply to SlowDragon

Hi SlowdragonThank you for your quick reply.

I was told years ago I have Hashimoto but nothing was really explained.

I have tried increasing my vitamin D but makes me feel rubbish. Does the magnesium help with that? I have been trying to raise it by going out in the sun when we get some.

I will try and get a full iron panel done through the doctors but they are not very helpful.

SlowDragon profile image
SlowDragonAdministrator

vitamin D

GP should prescribe 1600iu everyday for 6 months but with Hashimoto’s likely to need higher dose of at least 3000iu daily

Very important to also take a daily magnesium if taking vitamin D

NHS Guidelines on dose vitamin D required

panmerseyapc.nhs.uk/media/2...

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But with Hashimoto’s, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Can test via NHS private testing service

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Recipe ideas

bbc.co.uk/food/articles/mag...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

Lottieanne profile image
Lottieanne in reply to SlowDragon

Wow a lot to read up about.

I did notice when I was taking the vitamin D that my thyroid results improved. I will try taking it again and add some magnesium.

Thank you

SlowDragon profile image
SlowDragonAdministrator

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid supplements

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg)

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

Only add one supplement at a time then wait 10-14 days to assess before adding another

I suggest you start with vitamin B complex

Then magnesium (in afternoon or evening at least 4 hours away from levothyroxine)

Then finally vitamin D

Retest 6-8 weeks after adding last vitamin supplement

Lottieanne profile image
Lottieanne in reply to SlowDragon

Thank you I will try all this. A lot to take in but hopefully will get there.Thank you

SlowDragon profile image
SlowDragonAdministrator

Levo

Which brand of levothyroxine are you taking

Do you always get same brand

As you have Hashimoto’s are you on gluten free/dairy free diet

If not these are always worth trying

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

A trial of strictly gluten free diet is always worth doing

Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential

A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first as per NICE Guidelines

nice.org.uk/guidance/ng20/c...

Or buy a test online, about £20

Assuming test is negative you can immediately go on strictly gluten free diet 

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially) 

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

pubmed.ncbi.nlm.nih.gov/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

Similarly few months later consider trying dairy free too. Approx 50-60% find dairy free beneficial

With loads of vegan dairy alternatives these days it’s not as difficult as in the past

Post discussing gluten

healthunlocked.com/thyroidu...

If Ft3 remains low after all these steps…..then you will need small dose T3 prescribed alongside levothyroxine

Here’s link for how to request Thyroid U.K.list of private Doctors emailed to you, but within the email a link to download list of recommended thyroid specialist endocrinologists who will prescribe T3

Ideally choose an endocrinologist to see privately initially and who also does NHS consultations

thyroiduk.org/contact-us/ge...

Lottieanne profile image
Lottieanne in reply to SlowDragon

I am on Accord levothyroxine and always make sure I get that brand as I get on with it.

I had a coeliac test years ago, which was negative. I could try gluten free.

Thank you for all the information Slowdragon. Really appreciate it.

SlowDragon profile image
SlowDragonAdministrator in reply to Lottieanne

I could try gluten free.

You might be astonished at the improvements

Spend 2-3 weeks considering what you would eat instead of gluten at each meal before you take the plunge

No point being almost GF

Lottieanne profile image
Lottieanne in reply to SlowDragon

Yes will do.Thank you

Shellian profile image
Shellian in reply to Lottieanne

Hi Lottieanne, I also have trouble with taking Vit D tablets, most give me terrible headaches. Most probably because of all the expedients in them. However, I have been taking Doctor's Best Vit D3 1000iu tablets ( I take 2 per day) and found I am fine with these. They only contain extra virgin oil, and vit D3 the soft capsule shell contains gelatin, glycerin and purified water.

I also take a Vit K2 drops ( Vitamaze) but not every day.

I have yet to find a magnesium I can get on with.

Good luck .

SlowDragon profile image
SlowDragonAdministrator in reply to Shellian

Shellian

Have you tried Magnesium citramate by Thorne

Large capsules, but you can open and tip powder in small glass water

Lottieanne profile image
Lottieanne in reply to Shellian

Hi ShellianSorry I didn't reply earlier. I have been out all day.

Thank you. I will have to give them a try. It was the spray I used before as it avoids the gut but made me feel awful.

Thanks again

Anne

Shellian profile image
Shellian

Thank you Slow Dragon. I have been advised to take chelated Magnesium, ( by members of a MEN forum I am on, and also suggested on Parathyroid Uk website) the last one I tried was Solfar Chelated Magnesium but it does have lots of ingredients in it. Does it matter what type of Magnesium you take?

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