Latest test results

[Jasper79]

These are my latest test results

Vitamin D 93 (optimal 75-200)

Magnesium 0.99 (0.66-0.99)

Ferritin 377 (34-400)

Serum Folate 17.1 (9.83-60.8)

Active B12 93 (8.83-60.8)

TSH 0.02 (0.27-4.2)

Free T4 23.8 (12-22) 115%

Free T3 4.7 (3.1-6.8) 43.2%

T4 total 126 (66-181)

Anti-thyroglobulin Abs 31 (<115)

Anti-thyroidperoxidase Abs 183 (<34) was 232 on 18/09/2023

Cortisol (Random) 528 (165-507) 6am -10am

My TSH has dropped even more, and my FT4 has increased, but my FT3 has dropped slightly.

I have been gluten free for 8 weeks.

My main symptoms are chronic peripheral neuropathy, severe weight loss and digestive issues, mostly constipation.

Sample taken fasting, 8am before daily 100mcg of levothyroxine. My Methyl B complex includes 200mcg biotin, but, this is well below the critical level according to Blue Horizon so I did not stop the B Complex in order to get useful results for B12 and folate etc.

As usual your comments would be much appreciated.

Thanks

[greygoose]

Your TSH has dropped because your FT4 has increased. It is now too high and that is why your FT3 has dropped.

When the FT4 gets to a certain level, it starts converting to more rT3 than T3, so the FT3 can drop rather than rise. You are a very poor converter.

Poor conversion can be due to low nutrient levels, but your nutrients appear good - although I would want my B12 higher than that. It can also be due simply to having Hashi's, and there's nothing you can do about that. So, the only solution is to obtain some T3 to take with a reduced dose of levo.

Anti-thyroidperoxidase Abs 183 (<34) was 232 on 18/09/2023

Antibodies fluctuate all the time, it doesn't mean much, and certainly doesn't mean that your Hashi's is improving. It pretty much irrelevant.

[Jasper79 in reply to greygoose]

Thanks.

That confirms my rough suspicions. My FT3 only dropped from 4.8 to 4.7 but TSH drop and FT4 increase were more distinct for no change in levo dose.

I see that I put wrong range on B12 should be 37.5 - 150 but your point is noted.

[greygoose in reply to Jasper79]

Oh! You hadn't had an increase in levo? I didn't realise that. In that case, the increase in your FT4 is more likely to be due to your Hashi's than your dose. So, I wouldn't change my dose if I were you. Maybe stop if for a short while if you have symptoms of over-dosing, but do it on your own, don't get your doctor involved. Start taking the levo again when you start to feel hypo.

[SlowDragon Administrator]

severe weight loss

How much do you weigh

Perhaps you need to reduce levothyroxine a SMALL Amount and look at getting T3 prescribed alongside levothyroxine

Perhaps reduce levothyroxine by 25mcg PER WEEK

so 100mcg 6 days and 75mcg on one day per week

Exactly what B complex are you taking. You might need a separate B12 as well

[Jasper79 in reply to SlowDragon]

About 72kg. I am 190cm tall. i was 87kg in 8/22.

BioCare Methyl B Complex see:

biocare.co.uk/methyl-b-comp...

[SlowDragon Administrator in reply to Jasper79]

Well some people loose weight when on inadequate replacement dose

And guidelines on dose by weight suggest you were likely not on high enough dose

[Jasper79 in reply to SlowDragon]

Thanks for response.

My previous tests after increase to 100mcg had TSH at or very close to 0.1 and FT4 between 20 and 22. So fairly distinct change in latest results.

I do not see how I can increase levo with these results. T3 supplementation seems only option.

Sounds as though getting that is very hard work.

[SlowDragon Administrator in reply to Jasper79]

It is increasingly possible but only via endocrinologist initially

And would need private consultation initially

Here’s link for how to request Thyroid U.K.list of private Doctors emailed to you, but within the email a link to download list of recommended thyroid specialist endocrinologists who will prescribe T3

Ideally choose an endocrinologist to see privately initially and who also does NHS consultations

thyroiduk.org/contact-us/ge...

[Jasper79 in reply to SlowDragon]

Thanks. I have the list and have booked private appointment with one that fits your recommendation.