help with results

[Ajva]

hi everyone,

I am currently on 100mcg t4 (tirisont) and t3 compounded t3 9.5mcg.

I was originally on 1 grain armour and 50mcg tirisont but struggled to get bloods optimal t3 was going over range and t4 low.

I am not feeling great at all on synthetics. I have extreme fatigue, hair loss, histamine reactions and a lot of muscle pain, weakness, heart racing. My pharmacist said to reset the t3 stop for a week then restart. So I went back up to 5mcg and dropped the other 4.5mcg.

I am at a loss what to do as my antibodies are getting higher and higher on synthetics. I can’t raise my t3 anymore, my asthma is awful and I can hardly get out of bed, I am so bunged up from histamine reactions I can’t taste or smell (9 weeks ongoing)

Bloods were 24hours after meds, no biotin, fasting. I also take vit D, iron, b12 and coq10, probiotic.

I will get vit levels checked in next bloods.

Any help would be appreciated because this is really getting me down.

THYROGLOBULIN ANTIBODIES 1,834IU/mL

THYROID PEROXIDASE ANTIBODIES< 34 R500

[greygoose]

The fact that your antibodies are rising has nothing to do with your thyroid hormone being synthetic. Antibodies fluctuate all the time, but are usually highest after an immune system attack on the thyroid when they have a job to do, cleaning up the blood.

So, how did you feel went taking Armour and Tirosint? You weren't on a very high dose, so pretty certain that your FT3 going over-range had more to do with your Hashi's, and the immune system attacks on the thyroid, than the Armour.

My pharmacist said to reset the t3 stop for a week then restart.

My personal opinion is that your pharmacist is talking b***s. What does s/he mean by 'resetting the T3'?

I can’t raise my t3 anymore

Why?

I am so bunged up from histamine reactions

Are you taking an antihistamine?

Bloods were 24hours after meds

In which case, you have a false 'low' FT3. Had you left just 8 to 12 hours - which is what we recommend for T3 - it would have been higher in range.

[Ajva in reply to greygoose]

I did feel better on the armour and tirisont but still had symptoms of fatigue, hair loss etc. but I had some weeks I felt much better. I am on 9 weeks and I haven’t really had any good weeks. I know it takes us a while to adapt but my mood/ fatigue has been dreadful. I am tempted to swap back to 1 grain armour and add in 75mcg tirosint.

I do seem to be sensitive to t3 as I do have pots, MCAS & orthostatic hypertension. As soon as I go over 9.5mcg of t3 I can’t get my heart rate down even on my heart meds.

Antihistamines are an issue for me as I also have ME and I can’t seem to find one that suits me and doesn’t knock me out all day and night. So have given up on that.

Sorry don’t know why I put 24hours! I took last meds at 8:30pm and bloods were done at 9am!

Thank you for replying

[greygoose in reply to Ajva]

I think, if I were you, that I would swop back to Armour/Tirosint. Perhaps you just weren't on a high enough dose and that's why you still had symptoms.

Sorry don’t know why I put 24hours! I took last meds at 8:30pm and bloods were done at 9am!

OK, so those labs aren't worth very much, then. Impossible to say what your normal circulating levels of T4 and T3 are. They could be much lower. We always recommend a gap of 24 hours between the last dose of levo and the blood draw, and 8-12 hours for T3/Armour.

[Ajva in reply to greygoose]

I didn’t know this, thank you so much for taking the time to reply. I think your right I just wasn’t on a high enough dose. These are my bloods on armour and tirisont 1 grain + 50mcg tirisont

Pink

[greygoose in reply to Ajva]

Well, your FT3 is high, but if you took your Armour just before the blood draw then the results aren't reliable.

[Ajva in reply to greygoose]

no armour was 12 hours before these bloods.

This is the treason I came off of armour due to high t3. I am just concerned if I go back on it my t3 is just going to go over range.

[greygoose in reply to Ajva]

But, if you didn't feel over-medicated (you said you still had hypo symptoms) then it doesn't much matter if it goes a little over-range. Ranges are only a rough guide, not set in stone.

[Ajva in reply to greygoose]

yes you are right I always forget it is just a guide. I did have racing heart but once I took my heart meds things would calm down. I think my only option now is to go back on the combination as my body only seems to tolerate t3 in NDT form.

[Hedgeree]

Hi Ajva,

I realise I'll have to Google the thyroid and histamine connection as I don't know much about it but what causes your reactions? I'm fairly new to thyroid problems so curious.

Best wishes.

[SlowDragon Administrator]

Are you on strictly gluten free diet and dairy free diet

Or tried either

What were most recent vitamin results and how long since last tested

Not taking a daily vitamin B complex?

Or a magnesium supplement?

[Ajva]

yes I take magnesium and I am strictly gluten free and minimal dairy. I guess I need to completely cut the dairy as well now. Will post recent vitamins but have since added b complex the Thorne ones recommended on this page. I also have 3 electrolyte drinks a day which are the re-lyte ones which are the cleanest on the market. Thank you for replying to me. Vits last tested end of October but will retest everything in 6/8 weeks from now.

Pink

[SlowDragon Administrator in reply to Ajva]

Vitamin D and ferritin levels are rather low

[Ajva in reply to SlowDragon]

since those bloods I have started taking b complex, vit D and iron. Hopefully will get my levels up a bit soon