Hello,
I used to be on Armour and then Nature Throid back in 2015-2017, feeling generally quite well up until few years ago when my endo put me on Levo due to NT reformulation. Even with added t3 I was feeling dreadful, with labs high in range.
I have asked to be moved to Armour about a year ago and still tweaking with full endo support.
I take 2.5 grains of Armour combined with 12.5 Levo. These are my latest results after 6 weeks on this dose:
TSH 0.01 (always suppressed)
FT3 6.2 (3.1-6.8) 83%
FT4 16.8 (12-22) 48%
All tested after 24 hours of taking meds.
I can't sleep on this dose (can't fall asleep, wake early too, feeling hot, tired, puffy, hungry, despite being on low glycemic diet for the past 2 months and losing 10 pounds thanks to cutting out sugar etc.). Today I started to get irritated (I'm before my ovulation). Base of my neck started to swell frequently on this dose, my boyfriend has noticed it.
Previously was on slightly more Levo and less Armour, with results:
FT3 5.8 (3.1-6.8) 73%
FT4 16.4 (12-22) 44%
I was able to sleep largely, but was feeling a bit depressed or flat, started to get bad bloating and crushing fatigue after 7 weeks on it.
NDT is so much better for me, I am functional, but still struggling with many symptoms.
I had vitamin tests done recently, my vit D was optimal, have added a bit to bump it up for winter, my B12 is towards top of range, iron was top of range with ferritin just under half range, folate over towards top of range, I also take zinc, omegas, selenium on top of above vits.
Thank you for reading.
Any advice on what to do or what I'm doing wrong, is very welcome. It is very hard to know which symptoms is from under or overmedication.
Is your hypothyroidism due to autoimmune thyroid disease also called Hashimoto’s diagnosed by high thyroid antibodies or by ultrasound scan
Are you on strictly gluten free diet
Do you typically split the NDT into 2 or 3 doses through the day
Was test done as early as possible in morning before eating or drinking anything other than water and last 1/2 or 1/3rd of daily dose NDT 8-12 hours before test
Last dose levothyroxine 24 hours before test
Yes, I have Hashis, my antibodies fell dramatically on Armour, from over 1000 to circa 260 recently (TPO), ATG is first time ever in range
I have been on GF diet for 2 years, but unfortunately didn't do anything to my antibodies or how I felt. Being on low glycemic diet helped tremendously.
My endo asked me to split before and I did that for 18 months more less, disaster, I was fluctuating so wildly during the day, I had to be in bed most of the time. Once changed to one dose in the morning I saw big improvements in wellbeing.
So my test was 24 hours after meds, Armour and levo. Do you think my FT3 is too high? Or what could be causing depressive moods and bloating with FT4 44%, FT3 73% results?
Thank you for responding
If last dose NDT was 24 hours before test, you have falsely low Ft3 result…..so yes
Perhaps try less Armour and more levothyroxine
Do you take levothyroxine waking or bedtime?
Always get same brand levothyroxine at each prescription?
Oh right okay, so in reality could I be over range? May I ask where your FT4 or FT3 are more less after 24/12 hrs please? Just trying to see if people have high FT3s, or do they need them lower. My symptoms are almost identical for over and under
I have swapped some Levo for Armour in August/September, my FT4 was 44%, FT3 was 73% after 7 weeks, I was able to sleep, but was also very fatigued, bloated and felt depressed (from being fatigued maybe), also had these weird head spins/vertigo episodes, which have gone away when went back to higher Armour and lower Levo. I wonder if my FT4 at 44% might be too low?
Would you know if there are any people doing well on lower ft4 and higher ft3?
I take Levo at waking, I have tried taking it at night and I was wide awake 😞
Always the same, brand Eltroxin
Thank you! 😀
Perhaps you need to test adrenals
regeneruslabs.com/products/...
We are all different
You can read my profile. I take most of my levothyroxine at bedtime. Highest dose of T3 at bedtime too….I find it improves sleep
Unfortunately have no access to any saliva testing here, I'm not in the UK
I will read your profile, thank you for your help 
Thanks again, I have read your profile, it seems like your ft4 is higher than mine and Ft3 lower (both top third of range). Something I need to consider.