How to add T3 to my Synthroid medication? - Thyroid UK

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How to add T3 to my Synthroid medication?

Lucas22 profile image
4 Replies

Hello.

These are my blood results after taking 100 mcg of Synthroid for 6 weeks:

TSH: 2,19 uiu/ml – Ref: 0,35 – 4,94

Free T3: 2.15 pg/ml Ref: 1,88 – 3,18 20% in range

Free T4: 0,94 ng/dl Ref: 0.70 – 1.48 30% in range

In UK reference range:

Free T3: 3.3 pmol/l Ref: 3.1 – 6.8 5% in range

Free T4: 12.1 pmol/l Ref: 12-22 - 1% in range

My Cholesterol is high, at 243 mg/dl

Vitamin D3 is 65,4 ng/ml Ref: 30- 100

Ferritin is 171,22 ng/ml ref 21,81 – 274, 66 ng/ml

B12 is 569,2 pg/ml Ref: 197 – 771

Interesting is that my copper levels are low:

Serum copper: 72,2 mg/dl REF: 70 – 150 2% in range

Ceruloplasmim: 17,9 mg/dl Ref : 20 – 60 Below range

Can be the copper deficiency the reason that I can not tolerate T3 medication?

Whit these results, worring and desesparate about the low free t3 level, I began to take 5 mcg of T3, two times a day, and fell horrible, very, very tired, whit slow energy.

Should I reduce my dose of T4 before starting T3?

Just to add that I did a trial of hydrocortisone for 8 weeks, at 10 mg each day, and fell better energy whit it, but still was not capable of tolerating T3 medication, so I weaned of the cortisol medication whit no problem, and my morning serum cortisol is ok on the blood test, at 17 in a range of 8 to 20, so I not became dependent of it, thanks God.

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Lucas22
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4 Replies
Lalatoot profile image
Lalatoot

What makes you think you need T3? At the moment you need an increase in T4 medication as shown by a TSH above 2 and an ft4 less than halfway through range.You cannot transpose your set of results into a UK range. There is no standard UK range. That is why we just need the result and the range.

JAmanda profile image
JAmanda in reply to Lalatoot

Agree, raise your t4 and see how you are after 6 eeeks. It will save you a lot of trouble and expense if you can get well on t4 - as many do - you don't look like you have a problem converting but you'll see better in six weeks after a dose increase of t4. Really forget the T3 for now

shaws profile image
shawsAdministrator

Hi Lucas 22, I have looked at your Profile page but there's no history of your journey to be diagnosed as hypothyroid although you've had lots of posts. I'm sorry you have hypothyroidism.

The aim for us is to have a TSH around 1 or lower with both Frees (T4 and T3) in the upper part of the ranges.

Occasionally it is good to read about the member's particular journey to be diagnosed etc without them being asked repeat questions.

A higher cholesterol level is common in hypothyroidism because our system has slowed down and we're not yet on a sufficient dose. It should gradually reduce when we're taking sufficient replacement thyroid hormones.

You could increase your T4 dose if you wish as the aim is a TSH of 1 or lower. Also check your B12, Vit D, iron, ferritin and folate.

We can also get weary trying our best to relieve clinical symptoms ourselves.

When we do get to a dose that makes us well again it is a great feeling. I hope you do so in the near future.

You will know that T3 is the Active Thyroid Hormone needed in all of our T3 receptor cells, and T4 is the inactive hormone and has to convert to T3.

I couldn't tolerate levo at all and I felt very unwell on it. So our bodies are all different and it does take time to find a way to relieve all of the clinical symptoms.

One of the oldest thyroid hormone replacements is known as NDTs (natural dessicated thyroid hormones) but now difficult to source. Being made from animals' thyroid glands it saved lives from 1892 onwards. There were also no blood tests either but people recovered. Again, it doesn't suit everyone.

Regards.

SlowDragon profile image
SlowDragonAdministrator

You can’t rush thyroid hormones

Did you start on 100mcg levothyroxine..or build up to this dose

Far too early to consider adding T3

Getting settled on levothyroxine and fine tuning dose can take 6-12 months

Suggest you get 25mcg dose increase in levothyroxine and retest in another 8 weeks

Vitamin levels look good. Presumably you supplement?

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