Time do add t3?: Hello, these are my results... - Thyroid UK

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Time do add t3?

Lucas22 profile image
10 Replies

Hello, these are my results after 7 weeks taking 112 mcg of Sinthyroid. TSH: 0.49 REF: 0.35 - 4.9

Free T4: 1.09 ng/dl REF: 0.60 - 1.40 ng/dl

Free T3: 2.3 pg/ml REF: 2.3 - 4.10 pg/ml

Is it time to ask the doctor to add T3? How much? Do I have access to the dissected thyroid if I switch to it directly, would the correct dose be 1.5 grains?

Thank you.

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Lucas22 profile image
Lucas22
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SlowDragon profile image
SlowDragonAdministrator

Before considering adding T3 you need to get vitamin D, folate, ferritin and B12 tested and if results are not at GOOD levels improve by supplementing

GOOD vitamin levels can significantly improve conversion of Ft4 to Ft3

Do you have autoimmune thyroid disease also called Hashimoto’s diagnosed by high thyroid antibodies?

Lucas22 profile image
Lucas22 in reply to SlowDragon

Hello.These are my results:

Vitamin D3: 86 ng/ml REF: 20 - 100 (I take 5.000 iu every day).

Folate: 11,84 ng/ml REF: 4,6 - 18,70

Ferritin: 183,28 ng/ml REF: 21,81 - 274,66

B12: 643,9 pg/ml REF: 197 - 771

Anti-TPO: < 3 ui/ml REF: < 5,61

Anti-TBG: < 3 ui/ml REF: < 4,11

SlowDragon profile image
SlowDragonAdministrator in reply to Lucas22

So vitamin levels are good

Vitamin D might be a bit high. Perhaps consider reducing dose a little

Ft4 is 61.25% through range

You have room to try further increase in levothyroxine

Helpful calculator for working out percentage through range

chorobytarczycy.eu/kalkulator

Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine,

"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.

In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l.

Most patients will feel well in that circumstance.

But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.

This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."

(That’s Ft3 at 58% minimum through range)

You can obtain a copy of the articles from Thyroid UK email print it and highlight question 6 to show your doctor

 please email Dionne at

tukadmin@thyroiduk.org

Lucas22 profile image
Lucas22 in reply to SlowDragon

Thank you for your help.

Good to know that there are people who are just fine with T4, because researching it seems that T3 is needed by everyone.

So, I think I will increase my dose to 125 mcg, or up to 137 mcg, I will go until the free T4 gets high, forgetting the TSH. If that doesn't work, then it's time to try T3.

jrbarnes profile image
jrbarnes

Have you tried a higher dose than 112mcg? Have you tried another brand of thyroid medication other than Synthroid? I felt very unwell on Synthroid but I feel better on another brand. I am a 47 kg woman and I take more than 88mcg. Every 6 weeks you get blood tests done and then increase your medication until you feel better. I like my T4 levels to be high. I have many problems if they are low. I am not a doctor but your tests show you may need a higher dose.

Lucas22 profile image
Lucas22 in reply to jrbarnes

Yes, my doctor suggested switching from Synthorid to Levoid (a generic brand). He said that the generic is micronized and Synthroid is not.

jrbarnes profile image
jrbarnes in reply to Lucas22

I have not read of the difference in pills being micronized but I took generic brands for ten years and always did much better on them and had higher T4 levels. This is interesting information. thank you.

Jazzw profile image
Jazzw in reply to Lucas22

I think he’s barking up the wrong tree—I think you simply need a raise in Synthroid dose. Your FT4 has a way to go before it hits the top of the range, meaning there’s plenty of room for an increase in Synthroid.

I’d be looking to try 125mcg and even 150mcg Synthroid before adding the complication of T3.

Lucas22 profile image
Lucas22 in reply to Jazzw

Complication of t3, why?Also if I go to 125, 137 or 150 mcg of T4 my TSH will be supressed? It is already low.

Jazzw profile image
Jazzw in reply to Lucas22

T3’s not as easy to work with. It has a more immediate effect, not everyone finds it easy to take.

And a suppressed TSH doesn’t matter.

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