ryanj You're certainly not overmedicated, the aim of a treated hypo patient generally is for TSH to be 1 or below and FT4 and FT3 in the upper part of their respective reference ranges. Your TSH is in a reasonable place, your FT4 just about right (in the upper third of it's range) but your FT3 is way too low, it should be in the upper quarter of it's range but is right down at the very bottom. This indicates that you aren't converting T4 to T3 very well at all and need T3 added to your Levo.
What you are doing, though, instead of making FT3, you are in fact making reverse T3 - confirmed by your way over range rT3 result and the low ratio of 6.82 (over 20 is said to be where it should be).
Unfortunately, NHS doctors either don't know anything about this or refuse to recognise it.
How to lower rT3? Well, it's recommended to lower Levo and add T3, sometimes it's recommended to take T3 only for a few weeks to clear the rT3 then reintroduce Levo.
Here are some links I saved when I was looking into this which will help (not in any particular order, just plough through them):
You should get the idea from those.
What do you then do with that knowledge? That's a hard one. It's usually a case of go it alone because the NHS doesn't treat it because it doesn't accept it.
As for the rest of your results:
Thyroglobulin Antibody 429 (0-115)
Thyroid Peroxidase Antibody 185.8 (0-34)
Both types of antibodies are high confirming autoimmune thyroid disease aka Hashimoto's (autoimmune thyroiditis in doctor speak). You could point this out to your GP but they just say the treatment is no different. Actually it isn't. Hashi's is where antibodies attack the thyroid and gradually destroy it. It's the resulting Hypothyroidism that is treated.
What your GP probably won't know is that you can help reduce the antibodies by adopting a strict gluten free diet. Gluten contains gliadin which is a protein thought to trigger antibody attacks. Read about the gluten/thyroid connection here
Supplementing with selenium L-selenomethionine 200mcg daily and keeping TSH suppressed also help reduce the antibodies. Some people find they need to be dairy free too. But one step at a time!
Some reading about Hashi's:
Vitamin B12 291.2 (140-724)
Folate 6.4 (2.91 - 50 )
B12 and folate work together. Folate should be at least half way through the range, so 27+ with that range.
B12 under 500 can cause neurological problems. Recommended level is very top of range, even 900-1000.
You can buy some sublingual methylcobalamin lozenges 5000mcg (such as Solgar or Jarrow's) and take one daily. Finish the bottle then buy the 1000mcg dose as maintenance.
When taking B12 we need a B Complex to balance all the B vitamins. If you buy one with 400mcg methylfolate that will help raise your folate level. Look at Thorne Basic B (one daily) or Metabolics B Complex (two daily), both are good, the Metabolics has no fillers or unnecessary ingredients.
B vits should be taken in the morning, no later than lunchtime as they can be stimulating and may affect sleep if taken later in the day.
25 OH Vitamin D 52.5 (50-200)
Recommended level for Vit D is 100-150nmol/L. You can buy some D3 softgels (such as Doctor's Best) and take 5000iu daily for 3 months then retest. When you've reached the recommended level reduce to a maintenance dose. That could be 2000iu, maybe less in summer, we have to find our own maintenance dose by retesting once or twice a year to keep within the recommended range.
When taking D3 there are important cofactors needed which you can read about here
D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds.
Magnesium comes in different forms, check here to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds
Check the other cofactors too.
Ferritin 248 (13-150)
You will need to speak to your GP about this.
CRP 2.8 (0-5)
This is fine, CRP is an inflammation marker and you are well within range.
Sorry about all the reading, but you really need to learn as much as you can because the doctors rarely know enough to help us.