Please can I have some advice on recent blood tests before I go to see the g.p?
I have taken for some years 200mcg levo from g.p. plus 4.5 grains ndt which i source separately (g.p. knows about it but usually ignores) and felt well. I appreciate this is a hefty dose but b.p. ok and palpitations, anxiety, temp, head aches all none existent since on ndt. I also take b12 and use serenity cream, no iron.
However, couple months ago g.p. reduced levo down to 175mcg and will probs want it to go down further. Since reducing I have started to have resurgence of aches and pains and weariness.
Should I be continuing to reduce my dose given the test results below or not given the resurgence of hypo effects? Not sure how to interpret?
Thanks
Biochemistry
CRP 2.60 range <5.0mg/L
Ferritin 166.5 range 20 - 150ug/L
Thyroid Function
TSH<0.005 range 0.27 - 4.20IU/L
T4 Total 151.5 range 64.5 - 142.0nmol/L
Free T4 40.82 range 12 - 22pmol/L
Free T3 11.90 range 3.1 - 6.8pmol/L
Reverse T3 55.0 range 10 - 24ng/dL
Reverse T3 ratio 14.09 range Normal >15, Borderline 12-15, Low <12
Immunology
Anti-Thyroidperoxidase abs 574.2 range <34kIU/L
Anti-Thyroglobulin Abs115.6 range <115kU/L
Vitamins
Vitamin D (25 OH) 91 range Deficient <25nmol/L, Insufficient 25 - 50, Consider reducing dose >175
Your reverse T3 is high because you are over medicated with FT4 and FT3 considerably over range. FT4 should be <22 and FT3 should be <6.8. You need to substantially reduce dose.
Being over medicated can cause fatigue and musculoskeletal pain and make you feel very unwell.
Thyroid antibodies are positive for autoimmune thyroid disease (Hashimoto's) which causes 90% of hypothyroidism. 100% gluten-free diet may improve symptoms and reduce antibodies.
I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.
I think it's likely your T4 and T3 levels built up and reached a tipping point and it is that, rather than the 25mcg dose reduction, which has made you feel unwell.
If you get your dose of levo reduced until your Free T4 and Free T3 are in range, but testing shows you still have high levels of reverse T3, then I would suggest you get a full blood count and an iron panel done. There is a condition called Anaemia of Chronic Disease (or Anaemia of Chronic Inflammation) which may fit you, but it is a long shot on the basis of just the results you've listed and you need to know more.
The reason I'm mentioning this is because I had iron deficiency anaemia (IDA) and anaemia of chronic disease (ACD) together. My IDA lowered my ferritin, and the ACD increased it. It looked normal to a doctor's eyes. And yet my serum iron was in my boots and my TIBC was also well below range and my GP didn't know, because she never did an iron panel. Despite this my CRP (an inflammation indicator) was not high (nor is yours). But my reverse T3 was way over range. (Like yours.)
I realise I'm going out on a limb with the above. Don't take it too seriously. I'm not a doctor.
Results now mostly in range but feel worse but not consistently- tired, can't sleep properly, panic attacks, throbbing legs and hands, aches and pains etc. Sometimes one thing, sometimes another, but no consistency = very odd.
Please can you have a look and see what you think I should do next?
AKatieD, people often ignore updates to old threads on this forum. You should create a new thread and refer back to this one to increase your chance of getting replies.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Please help with my test results, esp the Reverse T3 ratio
Blood test
Trying to understand test results, please can anyone advise how to read them? 
