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ASCO 23 - Transdermal square-wave testosterone therapy
This might interest followers of BAT. As you no doubt know, Denmeade's BAT cycle is a 28-day modulation of testosterone [T] from ~2,000 ng/dL down to near castrate. The BAT cycle typically begins with a T-cypionate injection into muscle. In the new pilot study, T was delivered daily, transdermally
This might interest followers of BAT. As you no doubt know, Denmeade's BAT cycle is a 28-day modulation of testosterone [T] from ~2,000 ng/dL down to near castrate. The BAT cycle typically begins with a T-cypionate injection into muscle. In the new pilot study, T was delivered daily, transdermally
pjoshea13
in
Fight Prostate Cancer
1 year ago
Teeth and gums
Does anyone get gums flairing at night like you want your teeth removed and receding gums. Along with feet going red hot from feeling cold all day.
Does anyone get gums flairing at night like you want your teeth removed and receding gums. Along with feet going red hot from feeling cold all day.
minka
in
NRAS
1 year ago
Constant oral thrush on Fostair
I am constantly struggling with oral thrush on the roof of my mouth and now painfully in my throat. I take 2 puffs morning / 2 puffs night Fostair. I use a spacer, brush my teeth, rinse my mouth and it still keeps happening. Usually Nystatin works but this time (after finishing antibiotics) it’s not
I am constantly struggling with oral thrush on the roof of my mouth and now painfully in my throat. I take 2 puffs morning / 2 puffs night Fostair. I use a spacer, brush my teeth, rinse my mouth and it still keeps happening. Usually Nystatin works but this time (after finishing antibiotics) it’s not
GMcC2
in
Lung Conditions Community Forum
1 year ago
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Learning to live with PMR
My PMR started with strange stiffness, as if I'd been riding a horse, around the hips and buttocks in April/May 2022. I ignored it as far as possible, trying physio with no success. It was when I did the Dales Way in Yorkshire in June/July that I realised my fatigue, slowness and trouble getting over
My PMR started with strange stiffness, as if I'd been riding a horse, around the hips and buttocks in April/May 2022. I ignored it as far as possible, trying physio with no success. It was when I did the Dales Way in Yorkshire in June/July that I realised my fatigue, slowness and trouble getting over
Orange_2022
in
PMRGCAuk
2 years ago
Fistula
hi all. Has anyone who has a full hysterectomy to help clear stage 4 endometriosis ended up with a fistula. Unfortunately my partner has been told she has this. We ended up in A&E the other night due to my partner being in a lot of abdominal pain. Has blood tests done and a ct scan which has shown a
hi all. Has anyone who has a full hysterectomy to help clear stage 4 endometriosis ended up with a fistula. Unfortunately my partner has been told she has this. We ended up in A&E the other night due to my partner being in a lot of abdominal pain. Has blood tests done and a ct scan which has shown a
Helpwithpain1984
in
Endometriosis UK
1 year ago
Severely constipated what next?
I've been slightly constipated for weeks until 8 days ago . Then I just stopped. Been in severe pain since and tried every laxative. Been to doctors and she put me on docusate sodium. Now I'm on molaxole powder and having 8 sachets in 6 hours for faecal impaction. Still nothing at all. I'm in pain now
I've been slightly constipated for weeks until 8 days ago . Then I just stopped. Been in severe pain since and tried every laxative. Been to doctors and she put me on docusate sodium. Now I'm on molaxole powder and having 8 sachets in 6 hours for faecal impaction. Still nothing at all. I'm in pain now
BlueKeith
in
IBS Network
1 year ago
Effect of thyroid dysfunction on N-terminal pro-B-type natriuretic peptide levels: A systematic review and meta-analysis
Papers regarding the impact of inappropriate thyroid hormone levels keep coming out. It would be a miracle if endocrinologists showed any evidence of having read them. And incorporated the lessons into their practices. [i]
Effect of thyroid dysfunction on N-terminal pro-B-type natriuretic peptide
Papers regarding the impact of inappropriate thyroid hormone levels keep coming out. It would be a miracle if endocrinologists showed any evidence of having read them. And incorporated the lessons into their practices. [i]
Effect of thyroid dysfunction on N-terminal pro-B-type natriuretic peptide
helvella
Thyroid UK
in
Thyroid UK
1 year ago
alendronic Acid
Have been prescribed this by Rhuemy after waiting 3 1/2 years to see one. Have been down to 1/2 and 1 mg but symptoms returned. Have been on 3 mg for 12 months but Rhuemy has upped me to 5mg explaining about ardrenals and hopes this will fully wake them up. To reduced to 4mg in 8 weeks and then down
Have been prescribed this by Rhuemy after waiting 3 1/2 years to see one. Have been down to 1/2 and 1 mg but symptoms returned. Have been on 3 mg for 12 months but Rhuemy has upped me to 5mg explaining about ardrenals and hopes this will fully wake them up. To reduced to 4mg in 8 weeks and then down
Fatsdomino
in
PMRGCAuk
2 years ago
Cool, newly discovered AI search engine for supplements - SUPP.ai
While updating my files on curcumin formulations (Thanks to MB's recent post on Thracurmin for cognitive function), this website popped up in my search results. It was developed by the Allen Institute for AI (founded by Microsoft co-founder, Paul Allen) and is designed to search for supplement interactions
While updating my files on curcumin formulations (Thanks to MB's recent post on Thracurmin for cognitive function), this website popped up in my search results. It was developed by the Allen Institute for AI (founded by Microsoft co-founder, Paul Allen) and is designed to search for supplement interactions
cujoe
in
Fight Prostate Cancer
1 year ago
Mouth ulcer
I ve had a mouth ulcer now for 8 days. At first it was bothering me (not painful) now nothing as if its not even there. Would it be possible to get an advice of how to get rid of it? It’s around 3-4mm in size. The redness improved. I never had fever of anything just it bothers me when the tongue hits
I ve had a mouth ulcer now for 8 days. At first it was bothering me (not painful) now nothing as if its not even there. Would it be possible to get an advice of how to get rid of it? It’s around 3-4mm in size. The redness improved. I never had fever of anything just it bothers me when the tongue hits
Anonymous4991
in
Dentistry Health Support
1 year ago
Health update
Hello everyone, not sure if this helps... I went through genetic testing and they found my KMT2B gene activated. This is odd due to my age and how aggresive it is. My Dr has never seen this happen before. In actuality, there is nothing in written human history (as far as I know) that shows late stage
Hello everyone, not sure if this helps... I went through genetic testing and they found my KMT2B gene activated. This is odd due to my age and how aggresive it is. My Dr has never seen this happen before. In actuality, there is nothing in written human history (as far as I know) that shows late stage
Hidden
in
Functional Neurological Disorder - FND Hope
1 year ago
Am I at risk of having too much calcium in my blood?
diagnosed Sept. 21 now tapered to 2 mg. in the summer I was informed that I would require some dental treatment, possibly an implant. After speaking to my dentist about the risks involved, as I was taking Alandronic acid, which I have always disliked taking, I decided for better or worse (and especially
diagnosed Sept. 21 now tapered to 2 mg. in the summer I was informed that I would require some dental treatment, possibly an implant. After speaking to my dentist about the risks involved, as I was taking Alandronic acid, which I have always disliked taking, I decided for better or worse (and especially
Fetlar73
in
PMRGCAuk
2 years ago
Medical Anxiety through the roof
Have always had some degree of medical anxiety but nothing too debilitating. Last few years though as a result of some bad experiences (panic attack when sent for MRI, horrendous treatment in hospital when admitted following a bout of mild pancreatitis after having my gall bladder removed, difficult
Have always had some degree of medical anxiety but nothing too debilitating. Last few years though as a result of some bad experiences (panic attack when sent for MRI, horrendous treatment in hospital when admitted following a bout of mild pancreatitis after having my gall bladder removed, difficult
Menno1525
in
Anxiety and Depression Support
2 years ago
Why we add an AART drug to ADT?
In response to a post asking if adding enzalutamide to ADT is beneficial: Xtandi would increase T levels if not simultaneously using an LHRH ADT. It blocks AR in hypothalamus leading to perception of deficit and increased LH and testicular testosterone. So enzalutamide or apalutamide used without ADT
In response to a post asking if adding enzalutamide to ADT is beneficial: Xtandi would increase T levels if not simultaneously using an LHRH ADT. It blocks AR in hypothalamus leading to perception of deficit and increased LH and testicular testosterone. So enzalutamide or apalutamide used without ADT
MateoBeach
in
Fight Prostate Cancer
1 year ago
Is Xtandi necessary or even helping me?
This may be a stupid question but it's been on my mind for a while. I started on Prostap (Lupron) last July and my testosterone dropped to less than 1.0 by October while on just that. My PSA was also below 1.0 by then. My MO started me on Xtandi towards the end of October and my T and PSA appear to
This may be a stupid question but it's been on my mind for a while. I started on Prostap (Lupron) last July and my testosterone dropped to less than 1.0 by October while on just that. My PSA was also below 1.0 by then. My MO started me on Xtandi towards the end of October and my T and PSA appear to
Benkaymel
in
Fight Prostate Cancer
1 year ago
Squalene Monooxygenase
New Australian study below [1]. When tumors outgrow their blood supply, they experience hypoxia (insufficient oxygen). The normal defence for any cell is the generation of hypoxia-inducible factors [HIFs]. HIFs have cell survival functions. In PCa, HIF-1alpha is the most studied. It triggers the
New Australian study below [1]. When tumors outgrow their blood supply, they experience hypoxia (insufficient oxygen). The normal defence for any cell is the generation of hypoxia-inducible factors [HIFs]. HIFs have cell survival functions. In PCa, HIF-1alpha is the most studied. It triggers the
pjoshea13
in
Fight Prostate Cancer
1 year ago
Night Pain , Left -Flank
Hello All ,I have been on Eligard , Zytiga , pred since Feb. 2022 . I have this pain on left flank about 8 o'clock right below the rib cage for about 8 months . The pain is at night but hardly during the day .I had a CT scan , x-ray , MRi , and nothing shows . I e-mailed my MO at V.A. yesterday and she
Hello All ,I have been on Eligard , Zytiga , pred since Feb. 2022 . I have this pain on left flank about 8 o'clock right below the rib cage for about 8 months . The pain is at night but hardly during the day .I had a CT scan , x-ray , MRi , and nothing shows . I e-mailed my MO at V.A. yesterday and she
reconjj
in
Fight Prostate Cancer
1 year ago
Kwells / Hyoscine Hydrobromide contraindication
Does anyone happen to know why those with thyroid problems or heart conditions and those over 60, (I have all three) should speak to their doctor before taking these for motion sickness. A pharmacist who was aware of my medical conditions suggested Kwells for me. Only just read the pil in full. I haven
Does anyone happen to know why those with thyroid problems or heart conditions and those over 60, (I have all three) should speak to their doctor before taking these for motion sickness. A pharmacist who was aware of my medical conditions suggested Kwells for me. Only just read the pil in full. I haven
Aurealis
in
Thyroid UK
2 years ago
Anal fissure
I was diagnosed with Hypothyroidism several years ago. I also suffer from a painful anal fissure. I see from my research that the 2 maybe connected. Can anyone shed any light on this? Much appreciated…,
I was diagnosed with Hypothyroidism several years ago. I also suffer from a painful anal fissure. I see from my research that the 2 maybe connected. Can anyone shed any light on this? Much appreciated…,
Whizzer2
in
Thyroid UK
2 years ago
eXroid treatment for Piles
For those who suffer in silence, are petrified of surgery or other invasive treatments for piles and are fed up with the horrible pain (like me) - look at eXroid treatment. The website is exroid.com
For those who suffer in silence, are petrified of surgery or other invasive treatments for piles and are fed up with the horrible pain (like me) - look at eXroid treatment. The website is exroid.com
Crazymouse
in
IBS Network
2 years ago
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