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Experiences with
Saxagliptin / Metformin
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Is carvedilol making you cold?
I recently had my Carvedilol increased to 6.25mg twice a day. Lately, I am freezing to the bone. I turn my heating up and up and am still cold when everyone else says its like a sauna. I just wondered if anyone else has this? It could also be my recent addition of diabetes medication, Sitagliptin. Never
I recently had my Carvedilol increased to 6.25mg twice a day. Lately, I am freezing to the bone. I turn my heating up and up and am still cold when everyone else says its like a sauna. I just wondered if anyone else has this? It could also be my recent addition of diabetes medication, Sitagliptin. Never
Erish
in
British Liver Trust
3 months ago
Metformin again
cohort study https://www.nature.com/articles/s41391-024-00871-7
cohort study https://www.nature.com/articles/s41391-024-00871-7
Maxone73
in
Fight Prostate Cancer
1 day ago
I was diagnosed with GCA in November and was started on 40mg of prednisone.
I experienced really bad steroid induced diabetes which seems a bit more in control now. I am currently down to 8mg of Prednisone, then 120mg of Glyclazide and 500mg of Metformin for the diabetes In the last few days I have felt very depressed and anxious. I am not sure if this is related to my
I experienced really bad steroid induced diabetes which seems a bit more in control now. I am currently down to 8mg of Prednisone, then 120mg of Glyclazide and 500mg of Metformin for the diabetes In the last few days I have felt very depressed and anxious. I am not sure if this is related to my
Ambatu
in
PMRGCAuk
7 days ago
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raised HbA1c
I told my GP I hadn’t had any bloods done for well over a year when I went regarding a skin problem. She only ordered FBC and HbA1c. Unfortunately no ESR or U&E’s. I’m a bit upset as HbA1c gone up to 50 which puts me in diabetic realm. I try to keep carbs low but ‘could do better’. Just had message
I told my GP I hadn’t had any bloods done for well over a year when I went regarding a skin problem. She only ordered FBC and HbA1c. Unfortunately no ESR or U&E’s. I’m a bit upset as HbA1c gone up to 50 which puts me in diabetic realm. I try to keep carbs low but ‘could do better’. Just had message
Temeraire
in
PMRGCAuk
9 days ago
List of drugs by their metastatic prostate cancer cancer fighting properties
I asked ChatGPT to put the following drugs in order of their metastatic prostate cancer cancer fighting properties: Metformin, statins, mebendazole, vitamin C, doxycline, Silymarin and Esomeprazole (Nexium). Here is the answer from ChatGPT: Determining the order of these drugs based on their potential
I asked ChatGPT to put the following drugs in order of their metastatic prostate cancer cancer fighting properties: Metformin, statins, mebendazole, vitamin C, doxycline, Silymarin and Esomeprazole (Nexium). Here is the answer from ChatGPT: Determining the order of these drugs based on their potential
Seasid
in
Advanced Prostate Cancer
9 days ago
Metformin and clomid
I've just been prescribed metformin to take for 28 days and then clomid on day 2 - 6 of my period. I'm overweight and don't actually meet the criteria for it but it has been 7 years since trying so genuinely think she took pity on me. Has anyone had any success? I'm trying two cycles to see if I ovulate
I've just been prescribed metformin to take for 28 days and then clomid on day 2 - 6 of my period. I'm overweight and don't actually meet the criteria for it but it has been 7 years since trying so genuinely think she took pity on me. Has anyone had any success? I'm trying two cycles to see if I ovulate
Anonymous29
in
Fertility Network UK
16 days ago
Neuropathy and Osteoarthritis
Hello All, I am writing on behalf of my 89 year old mom who has been struggling with severe leg and back pain. Mom had Guillaune Barre Syndrome in 2009 resulting from the flu vaccine and both knee replacements prior to that. She is diabetic and otherwise cognitively fine. Her pain causes her syncope
Hello All, I am writing on behalf of my 89 year old mom who has been struggling with severe leg and back pain. Mom had Guillaune Barre Syndrome in 2009 resulting from the flu vaccine and both knee replacements prior to that. She is diabetic and otherwise cognitively fine. Her pain causes her syncope
Mira_Mira
in
Restless Legs Syndrome
18 days ago
When to take Metformin for maximum reduction of HbA1c?
I take metformin 850mg three times daily and no other anti-diabetic medicine. I have been taking it for some time without adverse effects and now, mainly because I am on prednisone, want to achieve maximum reduction of my HbA1c. When should I take the tablets to achieve this please?
I take metformin 850mg three times daily and no other anti-diabetic medicine. I have been taking it for some time without adverse effects and now, mainly because I am on prednisone, want to achieve maximum reduction of my HbA1c. When should I take the tablets to achieve this please?
kangaroojohn
in
Diabetes Research & Wellness Foundation
23 days ago
Hot weather intolerance - pmr, Pred or old age?
In a previous life - pre PMR - I was a real sun worshipper, loving every moment I could spend outside no matter how hot. Mediterranean holidays in the mid 30s were the best days of my life. I now seemed to have turned into my Mother who used to complain it was ‘far too hot’ the minute the temperature
In a previous life - pre PMR - I was a real sun worshipper, loving every moment I could spend outside no matter how hot. Mediterranean holidays in the mid 30s were the best days of my life. I now seemed to have turned into my Mother who used to complain it was ‘far too hot’ the minute the temperature
Mandyq
in
PMRGCAuk
24 days ago
What could be causing weight gain when bloods are optimum?
Hi all, I'd really like to get some advice re my results. I have been on a long journey (26 years) and never been able to tolerate thyroxine. After investigation it was discovered my reverse T3 was high and likely caused by me having the DIO2 variant. About three years ago I went private and absolutely
Hi all, I'd really like to get some advice re my results. I have been on a long journey (26 years) and never been able to tolerate thyroxine. After investigation it was discovered my reverse T3 was high and likely caused by me having the DIO2 variant. About three years ago I went private and absolutely
Tiredofthis77
in
Thyroid UK
28 days ago
Blood test timing when insulin dependent
I have been underactive ever since RAI over thirty years ago. Unfortunately, due to poor management of thyroxine dosage (consultant didn't know what he was doing and left me to GP) I gained a lot of weight which just wouldn't shift. So I was diagnosed with type 2 diabetes and was prescribed Metformin
I have been underactive ever since RAI over thirty years ago. Unfortunately, due to poor management of thyroxine dosage (consultant didn't know what he was doing and left me to GP) I gained a lot of weight which just wouldn't shift. So I was diagnosed with type 2 diabetes and was prescribed Metformin
LynetteP
in
Thyroid UK
1 month ago
Pathologic fracture of Iliac crest
Such a complicated journey...but essentially after successful spinal stenosis surgery in March,Ienjoyed a few weeks of good health and mobility. I continued Piqray and had to start metformin. In May, I began experiencing increasing pain in my right hp where the cancer is located. Scans were ordered
Such a complicated journey...but essentially after successful spinal stenosis surgery in March,Ienjoyed a few weeks of good health and mobility. I continued Piqray and had to start metformin. In May, I began experiencing increasing pain in my right hp where the cancer is located. Scans were ordered
Dragonfly2
in
SHARE Metastatic Breast Cancer
1 month ago
Decapeptyl SR and the side effects with other medications, which has caused such bad rib cage structure effects?
I have pectus carinatum/pigeon chest from when aged 10 left over from meningitis, I also have Juvenile Myoclonic Epilepsy, not a good mixture, as such have probably broken every rib in my already weakened chest? I was diagnosed with Prostate Cancer in 2022, but the Decapeptyl SR injections considerably
I have pectus carinatum/pigeon chest from when aged 10 left over from meningitis, I also have Juvenile Myoclonic Epilepsy, not a good mixture, as such have probably broken every rib in my already weakened chest? I was diagnosed with Prostate Cancer in 2022, but the Decapeptyl SR injections considerably
Adlon57
in
Bone Health and Osteoporosis UK
1 month ago
Do I need to be medicated with these results ?
**EDITED 17.06.24 TO ADD MORE SYMPTOMS I REMEMBERED**
My Private Doctor wants to trial me on combined T4/T3.
Lab Results
Feb 2023
TSH - 1.33 (0.27-4.2) T4 - 18.9 (12-22) T3 - 4.6 (3.1-6.8) D3 - 158 (50-200) Iron - not tested Ferritin - not tested B12 - 204 (25.1-165
**EDITED 17.06.24 TO ADD MORE SYMPTOMS I REMEMBERED**
My Private Doctor wants to trial me on combined T4/T3.
Lab Results
Feb 2023
TSH - 1.33 (0.27-4.2) T4 - 18.9 (12-22) T3 - 4.6 (3.1-6.8) D3 - 158 (50-200) Iron - not tested Ferritin - not tested B12 - 204 (25.1-165
ShiningStar77
in
Thyroid UK
1 month ago
Development of metformin resistance in PCa cells after long-term treatment
I just came across this article that seems to suggest PC cells develop resistance to metformin after "long term use" which can be reversed by withholding metformin for 30 days: https://www.nature.com/articles/s41392-023-01516-2 Under the Results section: >Metformin resistance was suggested to be associated
I just came across this article that seems to suggest PC cells develop resistance to metformin after "long term use" which can be reversed by withholding metformin for 30 days: https://www.nature.com/articles/s41392-023-01516-2 Under the Results section: >Metformin resistance was suggested to be associated
DrawingSnowmen
in
Advanced Prostate Cancer
1 month ago
Methionine restricted diet for recurring PSA and positive PMSA pet scan w/ 1 bone met
quick to the point. PSMA pet showed 1 L2 small met and some lymph activity. My PSA went from 2.01 to 2.9 in one month. after doing some research on diets and supplements . I found that the keto diet is extremely high in the amino acid methionine and I made it worse trying to reduce my blood pressure
quick to the point. PSMA pet showed 1 L2 small met and some lymph activity. My PSA went from 2.01 to 2.9 in one month. after doing some research on diets and supplements . I found that the keto diet is extremely high in the amino acid methionine and I made it worse trying to reduce my blood pressure
Eieio
in
Advanced Prostate Cancer
1 month ago
Sitagliptin
Hi all Does anyone know if this medicine for type 2 diabetes has any effect on RLS/PLMD. I did a search and could not find it. I have been on 2 diabetic mecicines and both have sent my legs crazy or has other side effects. Thanks.
Hi all Does anyone know if this medicine for type 2 diabetes has any effect on RLS/PLMD. I did a search and could not find it. I have been on 2 diabetic mecicines and both have sent my legs crazy or has other side effects. Thanks.
CORFUORBUST
in
Restless Legs Syndrome
8 months ago
Metformin during pregnancy
I heard this dilemma so much around metformin, whether or not to take it during pregnancy. Is someone has pcos and insulin resistance, will it be better to continue metformin after conceiving naturally? Does it have any side effects? No one gives a concrete answer to this. Advices much appreciated
I heard this dilemma so much around metformin, whether or not to take it during pregnancy. Is someone has pcos and insulin resistance, will it be better to continue metformin after conceiving naturally? Does it have any side effects? No one gives a concrete answer to this. Advices much appreciated
Hope_1996
in
Fertility Network UK
1 month ago
Anyone know about Dr's or consultants prescribing metformin for endometriosis?
I recently got access to ALL my medical records from the consultants I had been referred to over the years and saw that in the past I had been prescribed metformin, altavita and amitryptaline at the same time by an endocrinologist. I presumed at the time it was for my underactive Thyroid and wasn't on
I recently got access to ALL my medical records from the consultants I had been referred to over the years and saw that in the past I had been prescribed metformin, altavita and amitryptaline at the same time by an endocrinologist. I presumed at the time it was for my underactive Thyroid and wasn't on
Escapologygirl
in
Endometriosis UK
2 months ago
is ‘just thrush’ reallly this painful?
Briefly: 77 years old female three normal births early menopause due to treatment for Bladder Cancer at age 40. Free and clear as of last check 10 years ago. No Hormones taken ever. 3 years ago started horrendous uncontrollable diarrhoea all test done no answer’get on with it’ even loosing control on
Briefly: 77 years old female three normal births early menopause due to treatment for Bladder Cancer at age 40. Free and clear as of last check 10 years ago. No Hormones taken ever. 3 years ago started horrendous uncontrollable diarrhoea all test done no answer’get on with it’ even loosing control on
Nonameme
in
BASHH
2 months ago
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