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The use of combination therapy in Ireland
This downloable paper shows that Irish doctors are quite ready to prescribe T4/T3 combination therapy and are not dissuaded from doing so:
Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients: A THESIS questionnaire survey of members of the Irish Endocrine Society
December 2022
This downloable paper shows that Irish doctors are quite ready to prescribe T4/T3 combination therapy and are not dissuaded from doing so:
Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients: A THESIS questionnaire survey of members of the Irish Endocrine Society
December 2022
diogenes
in
Thyroid UK
1 year ago
Enhertu next treatment??
I have been posting a lot lately. Thank you everyone for all your help. Some history…..I have lobular MBC. I have Mets in stomach lining, liver, and hip bone. got almost a year and a half from ibrance. After that I was on Exemestane and Everolimus for 2 months and all my liver mets grew. My
I have been posting a lot lately. Thank you everyone for all your help. Some history…..I have lobular MBC. I have Mets in stomach lining, liver, and hip bone. got almost a year and a half from ibrance. After that I was on Exemestane and Everolimus for 2 months and all my liver mets grew. My
Ticket123
in
SHARE Metastatic Breast Cancer
11 months ago
The T3-4-Hypo trial
I think this has previously been mentioned. [i][/i] [i]
The T3-4-Hypo trial
[/i] [i]A Dutch national randomized placebo-controlled double-blind multicenter trial of LT4/LT3 combination therapy in patients with autoimmune hypothyroidism.[/i] https://t3-4-hypotrial.nl/english/ I note that the
I think this has previously been mentioned. [i][/i] [i]
The T3-4-Hypo trial
[/i] [i]A Dutch national randomized placebo-controlled double-blind multicenter trial of LT4/LT3 combination therapy in patients with autoimmune hypothyroidism.[/i] https://t3-4-hypotrial.nl/english/ I note that the
helvella
Thyroid UK
in
Thyroid UK
1 year ago
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Blood Test Result
After being on ADT for two weeks, my blood test shows my Testosterone to be 109 (low). I guess this is the goal of ADT, to lower my Testosterone. However, in the same test result, the following was flagged as either low or high. Can my ADT attributed to the issues flagged by the test result? RBC
After being on ADT for two weeks, my blood test shows my Testosterone to be 109 (low). I guess this is the goal of ADT, to lower my Testosterone. However, in the same test result, the following was flagged as either low or high. Can my ADT attributed to the issues flagged by the test result? RBC
toyman79912
in
Advanced Prostate Cancer
11 months ago
Requesting Help to Develop Bespoke BAT
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
CurrentSEO
in
Fight Prostate Cancer
11 months ago
Requesting Help to Develop Bespoke BAT Protocol
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
Brief history. Diagnosed in July 2020 with oligometastatic PC with PSA 1,600… picked at 13,000+ after biopsy, Gleason 8. One previous bone femur lesion ( succesfuly treated by SBRT and 3 pelvic lymphodes (succesfuly treated by Lu-177). Discordance and previous existence of FDG+/PSMA- lesions. Volume
CurrentSEO
in
Advanced Prostate Cancer
11 months ago
PSA Went Up After Start of ADT
I had my prostate removed in January. I started ADT about two weeks ago and just received my second session of radiation. Prior to starting ADT, my PSA was .37 and a month prior was .22. I had blood drawn right after my first session of radiation yesterday and got the result back today. My PSA has
I had my prostate removed in January. I started ADT about two weeks ago and just received my second session of radiation. Prior to starting ADT, my PSA was .37 and a month prior was .22. I had blood drawn right after my first session of radiation yesterday and got the result back today. My PSA has
toyman79912
in
Advanced Prostate Cancer
11 months ago
Estradiol levels high? and progesterone help!
Good morning! I'm 47, and have been on HRT for about 2 years. I have evorel 50 and 2 weeks of micronised progesterone every 12 weeks. I also have under active thyroid disease and have to have vitamin b12 injections, so some symptoms can get confused! HRT has managed hot flushes and other peri-specific
Good morning! I'm 47, and have been on HRT for about 2 years. I have evorel 50 and 2 weeks of micronised progesterone every 12 weeks. I also have under active thyroid disease and have to have vitamin b12 injections, so some symptoms can get confused! HRT has managed hot flushes and other peri-specific
Laundretta
in
Menopause and Perimenopause Support
11 months ago
At Rock bottom
So.. I’ve reached 50, I started Peri menopause a few years ago now. The beginning of last year I was really struggling to remember things, my mental health was awful, my periods all over the place but when they came I was literally flooding and some days unable to leave the house as it was so bad. I
So.. I’ve reached 50, I started Peri menopause a few years ago now. The beginning of last year I was really struggling to remember things, my mental health was awful, my periods all over the place but when they came I was literally flooding and some days unable to leave the house as it was so bad. I
sickandsore
in
Menopause and Perimenopause Support
11 months ago
Docetaxel and deterioration
My oncologist last Tuesday informed me that: 1. The drug I am on, Xtandi, is going to fail. The is hoping it will manage the rest of this year and the next. 2. After that, all she has in her armoury is docetaxel, with 6 - 10 cycles spaced at 3 weekly intervals. She expressed concern that, as I
My oncologist last Tuesday informed me that: 1. The drug I am on, Xtandi, is going to fail. The is hoping it will manage the rest of this year and the next. 2. After that, all she has in her armoury is docetaxel, with 6 - 10 cycles spaced at 3 weekly intervals. She expressed concern that, as I
BrentW
in
Advanced Prostate Cancer
11 months ago
ET and HRT
HiHas anyone with ET also taken HRT. I was prescribed Oestrogen pessaries to treat post menopausal bladder issues , I will obviously check with haematologist, but as all vary with some erring on side of caution, was wondering if anyone else was given the go ahead. I really do need some help with the
HiHas anyone with ET also taken HRT. I was prescribed Oestrogen pessaries to treat post menopausal bladder issues , I will obviously check with haematologist, but as all vary with some erring on side of caution, was wondering if anyone else was given the go ahead. I really do need some help with the
jodary
in
MPN Voice
11 months ago
Advice on metavive or hrt
Hi allI just wanted to ask whether anyone has had good results with metavive? Or whether hrt is the way to go. I've just had review with nhs endocrinologist. I've been on 100 t4 and 15 t3 since December last year. My bloods are TSH <0.01 (0.35-3.94) T4 11.4 (8-19.1) T3 5.7 (2.4-6) I had bloods
Hi allI just wanted to ask whether anyone has had good results with metavive? Or whether hrt is the way to go. I've just had review with nhs endocrinologist. I've been on 100 t4 and 15 t3 since December last year. My bloods are TSH <0.01 (0.35-3.94) T4 11.4 (8-19.1) T3 5.7 (2.4-6) I had bloods
BiscuitBaby
in
Thyroid UK
11 months ago
PSA Nadir After RT+ADT for Prostate Cancer Predicts Outcomes
monthshttps://www.renalandurologynews.com/home/news/urology/prostate-cancer/psa-nadir-after-rtadt-for-prostate-cancer-predicts-outcomes/?utm_medium=email&utm_source=rasa_io&utm_campaign=newsletter One could read this and construe that that 6 months of ADT would be as good as as 24-36 but of course
monthshttps://www.renalandurologynews.com/home/news/urology/prostate-cancer/psa-nadir-after-rtadt-for-prostate-cancer-predicts-outcomes/?utm_medium=email&utm_source=rasa_io&utm_campaign=newsletter One could read this and construe that that 6 months of ADT would be as good as as 24-36 but of course
Scout4answers
in
Advanced Prostate Cancer
11 months ago
Castrate Resistance Mechanism & Statins
https://medicine.wustl.edu/news/study-reveals-how-treatment-resistant-prostate-cancer-supplies-its-own-hormonal-fuel/ Good afternoon chaps - read the above article re mechanisms leading to castrate resistance ; In summary it appears to conclude that the PCa tumours sense the lack of testosterone
https://medicine.wustl.edu/news/study-reveals-how-treatment-resistant-prostate-cancer-supplies-its-own-hormonal-fuel/ Good afternoon chaps - read the above article re mechanisms leading to castrate resistance ; In summary it appears to conclude that the PCa tumours sense the lack of testosterone
PSA680
in
Advanced Prostate Cancer
11 months ago
Goat whey, casein, IGF-1 etc. - Do they promote or slow cancer growth?
I've been trying for many years to decide whether to take a protein powder supplement to help maintain muscle mass. Since I started on ADT in 2016, I've lost 30 pounds. I don't know how much is due to the ADT, and how much is due to my diet. I'm 172 pounds now. I was muscular and athletic at 202,
I've been trying for many years to decide whether to take a protein powder supplement to help maintain muscle mass. Since I started on ADT in 2016, I've lost 30 pounds. I don't know how much is due to the ADT, and how much is due to my diet. I'm 172 pounds now. I was muscular and athletic at 202,
GeorgeGlass
in
Advanced Prostate Cancer
11 months ago
Asking employer for accommodations - yes, no, maybe?
Quick background:BCRed about 2.5 years after adjuvant RT to prostatic bed after RARP. Started Firmagon in May 2022 after nothing seen on PSMA PET/CT with PSA at 0.4. Switched to Orgovyx in November since injection site reaction was compromising QoL. Just before BCR was detected, I started taking adderall
Quick background:BCRed about 2.5 years after adjuvant RT to prostatic bed after RARP. Started Firmagon in May 2022 after nothing seen on PSMA PET/CT with PSA at 0.4. Switched to Orgovyx in November since injection site reaction was compromising QoL. Just before BCR was detected, I started taking adderall
farmanerd
in
Advanced Prostate Cancer
11 months ago
Levothyroxine and HRT
Hi, I've just had some bloods done due to weight gain, feeling generally unwell, menopausal symptoms and also to review my underactive thyroid, I'm on 125mcg Levothyroxine. My T4 is 21 (range 11.20-20.20), TSH 0.04 (range 0.27-4.20), FSH has been measured at 55.9. My GP wants to start me on HRT. Does
Hi, I've just had some bloods done due to weight gain, feeling generally unwell, menopausal symptoms and also to review my underactive thyroid, I'm on 125mcg Levothyroxine. My T4 is 21 (range 11.20-20.20), TSH 0.04 (range 0.27-4.20), FSH has been measured at 55.9. My GP wants to start me on HRT. Does
PinkPants3
in
Thyroid UK
11 months ago
Any advice would be appreciated
Three years ago my dear friend was diagnosed with metastisized prostate cancer. Stage 8. Cancer had spread to bone but not to lymph nodes or organs. HealthUnlocked helped me, as primary support person, to navigate options, to formulate useful questions for our medical team, to anticipate treatment side
Three years ago my dear friend was diagnosed with metastisized prostate cancer. Stage 8. Cancer had spread to bone but not to lymph nodes or organs. HealthUnlocked helped me, as primary support person, to navigate options, to formulate useful questions for our medical team, to anticipate treatment side
SupportP
in
Advanced Prostate Cancer
11 months ago
Pluvicto and tongue and taste issues
Previously posted the below message. Just had third Pluvicto infusion (6/9) and tongue and taste issue has gotten worse. Tried all suggestions from Oral Medicine at Dana and suggestions on HealthUnlocked. Has anyone experienced this issue and if so, any further suggestions. Your input always appreciated
Previously posted the below message. Just had third Pluvicto infusion (6/9) and tongue and taste issue has gotten worse. Tried all suggestions from Oral Medicine at Dana and suggestions on HealthUnlocked. Has anyone experienced this issue and if so, any further suggestions. Your input always appreciated
TTJJ1
in
Advanced Prostate Cancer
11 months ago
Really interesting article on central hypothyroidism
Sorry if this article has already been posted but I found this a very helpful discussion and guidance piece https://thyroidpatients.ca/2020/01/12/screening-central-hypo-during-thyroid-therapy/ I'm preparing for battle over my suppressed tsh of over a decade's standing when I see the endocrinologist next
Sorry if this article has already been posted but I found this a very helpful discussion and guidance piece https://thyroidpatients.ca/2020/01/12/screening-central-hypo-during-thyroid-therapy/ I'm preparing for battle over my suppressed tsh of over a decade's standing when I see the endocrinologist next
Reefseeker
in
Thyroid UK
1 year ago
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