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Studies help explain why some prostate cancers become resistant to hormone therapy
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
zeitgeistxx
in
Advanced Prostate Cancer
8 months ago
stopping HRT patches
hello, I hope this is not an insensitive question. I’m waiting for a date for a colonoscopy and a gyne referral following 10 months of [i]malaise [/i]with cancer flag bloods in February and ongoing symptoms of bloating, spotting, RHS side pelvic sharp stabbing pain, period like pain (61) and back ache
hello, I hope this is not an insensitive question. I’m waiting for a date for a colonoscopy and a gyne referral following 10 months of [i]malaise [/i]with cancer flag bloods in February and ongoing symptoms of bloating, spotting, RHS side pelvic sharp stabbing pain, period like pain (61) and back ache
Stills
in
My Ovacome
8 months ago
Dig the low, low, low, low, lowdown! PSA Update 💙
https://youtu.be/CWW6DRscQIc?si=61otmpzO3ugAJB0D 1.7 Woo Hoo😂🤙 The lowest PSA since 01/2018 @1.3 (552.2, 633, 840.2 in 2014) 39 chemos & 28 IMRT radiation sessions What a crazy 9 yr Rollercoaster Long Strange trip it's been 🤣 I ain't complaining Ain't Misbehavin, Stormy Weather on the
https://youtu.be/CWW6DRscQIc?si=61otmpzO3ugAJB0D 1.7 Woo Hoo😂🤙 The lowest PSA since 01/2018 @1.3 (552.2, 633, 840.2 in 2014) 39 chemos & 28 IMRT radiation sessions What a crazy 9 yr Rollercoaster Long Strange trip it's been 🤣 I ain't complaining Ain't Misbehavin, Stormy Weather on the
dockam
in
Advanced Prostate Cancer
6 months ago
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Stuck. Help Plz.
Hi, thanks for all the info here. I’ve been reading for hours, think I’ve tried to absorb too much too quickly as my brain feels like it’s going to pop! I’ve been feeling nauseous with low pain headaches for a month so had a GP apt last week. Bloods were done and all appears normal apart from thyroid
Hi, thanks for all the info here. I’ve been reading for hours, think I’ve tried to absorb too much too quickly as my brain feels like it’s going to pop! I’ve been feeling nauseous with low pain headaches for a month so had a GP apt last week. Bloods were done and all appears normal apart from thyroid
Hidden
in
Thyroid UK
8 months ago
FDA approves niraparib and abiraterone acetate plus prednisone for BRCA-mutated metastatic castration-resistant prostate cancer - 08/11/2023
On August 11, 2023, the Food and Drug Administration approved the fixed dose combination of niraparib and abiraterone acetate (Akeega, Janssen Biotech, Inc.), with prednisone, for adult patients with deleterious or suspected deleterious BRCA-mutated castration-resistant prostate cancer (mCRPC), as determined
On August 11, 2023, the Food and Drug Administration approved the fixed dose combination of niraparib and abiraterone acetate (Akeega, Janssen Biotech, Inc.), with prednisone, for adult patients with deleterious or suspected deleterious BRCA-mutated castration-resistant prostate cancer (mCRPC), as determined
cujoe
in
Fight Prostate Cancer
11 months ago
Advice about recent NDT thyroid blood tests and high SHBG
Hi there! Is there any connection between high SHBG and taking NDT thyroid medication? I've been feeling better than ever on my Erfa thyroid medication and I don't feel over medicated at all, but I had high SHBG. My estradiol also seems high. I've read that one reason for high SHBG can be hyperthyroidism
Hi there! Is there any connection between high SHBG and taking NDT thyroid medication? I've been feeling better than ever on my Erfa thyroid medication and I don't feel over medicated at all, but I had high SHBG. My estradiol also seems high. I've read that one reason for high SHBG can be hyperthyroidism
RatherBeSleeping
in
Thyroid UK
8 months ago
Break from ADT or not?
Hi everyone, my Dad was recommended 18-24 months of Lupron/Zytiga/Prednisone after Radiation Therapy. We reached that time and MO said that is up to my Dad if he wants to continue the treatment or not. Lately my dad had high blood pressure over 200 and he ended up in ER, but now the blood pressure is
Hi everyone, my Dad was recommended 18-24 months of Lupron/Zytiga/Prednisone after Radiation Therapy. We reached that time and MO said that is up to my Dad if he wants to continue the treatment or not. Lately my dad had high blood pressure over 200 and he ended up in ER, but now the blood pressure is
Simonapo
in
Advanced Prostate Cancer
8 months ago
Blood Pressure experience and views sought
Hi allI have been feeling ropey,v lethargic and a bit slow for a few months now, despite increase in Levothyroxine. I had attributed this to constant blood loss(months) following HRT which didn't suit me,however this stopped 2 months ago. Previous blood tests showed haemoglobin on the low side so have
Hi allI have been feeling ropey,v lethargic and a bit slow for a few months now, despite increase in Levothyroxine. I had attributed this to constant blood loss(months) following HRT which didn't suit me,however this stopped 2 months ago. Previous blood tests showed haemoglobin on the low side so have
Pebble23
in
Thyroid UK
8 months ago
ADT therapy and breast enlargement
Hello, any feedback on outlook for breast enlargement with ADT therapy ..currently taking Lupron and Bicalutmide? Diagnosed in Japan this June , 56, Gleason 7 , 4+3, PSA18, most likely no metastasis..was fairly fit…165, 5’10 but gaining weight and some man boobs. I generally was working out 4 days a
Hello, any feedback on outlook for breast enlargement with ADT therapy ..currently taking Lupron and Bicalutmide? Diagnosed in Japan this June , 56, Gleason 7 , 4+3, PSA18, most likely no metastasis..was fairly fit…165, 5’10 but gaining weight and some man boobs. I generally was working out 4 days a
Yokohama2023
in
Advanced Prostate Cancer
8 months ago
What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
10 months ago
Stopped taking Orgovyx 7 months ago (T recovery only 80 baseline was 286 ) do I start TRT? am I risking Reoccurrence?
I stopped RT (IMRT 20 tx ) on 2/28/23. I stopped orgovyx (4 months) on 5/31/23 . (It has now been 6 months since stopping orgovyx. My T has recovered to 80. My baseline is 286.(which was fine) Advised when given choice of adt -4 months of orgovyxx- then 4 months for recovery of T- that didn't happen
I stopped RT (IMRT 20 tx ) on 2/28/23. I stopped orgovyx (4 months) on 5/31/23 . (It has now been 6 months since stopping orgovyx. My T has recovered to 80. My baseline is 286.(which was fine) Advised when given choice of adt -4 months of orgovyxx- then 4 months for recovery of T- that didn't happen
JWS13
in
Advanced Prostate Cancer
8 months ago
HRT and migraines
I'd be interested to know if there are women out there who can definitely say that taking HRT has helped them with migraines. I know that the research says that there is no evidence that it helps, if anything, probably makes it worse. Or were you prescribed some medication for menopause and it actually
I'd be interested to know if there are women out there who can definitely say that taking HRT has helped them with migraines. I know that the research says that there is no evidence that it helps, if anything, probably makes it worse. Or were you prescribed some medication for menopause and it actually
Chleo11
in
National Migraine Centre
8 months ago
Restless legs.
I have severe restless legs, as previously discussed within this forum. Over the past few years intercourse has become quite painful - middle age woman syndrome. Recently my GP started me on 10 milligrams estradiol vagifem pessaries. I understand that hrt has a significant impact on rls. My rls was
I have severe restless legs, as previously discussed within this forum. Over the past few years intercourse has become quite painful - middle age woman syndrome. Recently my GP started me on 10 milligrams estradiol vagifem pessaries. I understand that hrt has a significant impact on rls. My rls was
Trish8433
in
Restless Legs Syndrome
8 months ago
methotrexate
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling out
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling out
tresa56
in
NRAS
10 months ago
Favorite RA drug? I have so much anxiety about trying a new one
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling
I am currently on hydroxychloroquine and my doctor wants me to move to Methotrexate . I am stil getting hand pain and foot pain ect on the hydroxy.... The side effects of all these drugs terrifies me.. Anyone on Methotrexate and like it? Do you have more energy? Do you drink alcohol...Hair falling
tresa56
in
FieryBones - RA Community
10 months ago
Recurrence after prostatectomy
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
Fred312
in
Advanced Prostate Cancer
8 months ago
fed up of feeling so rubbish!!
Following up from previous posts: Brief history : diagnosed with hypothyroidism in March after going to the DRs initially thinking my HRT needed tweaking, awful brain fog, hair loss, brittle peeling ridged nails, cold feet but extreme sweating at times incl night sweats, dry flaky skin, horrible joint
Following up from previous posts: Brief history : diagnosed with hypothyroidism in March after going to the DRs initially thinking my HRT needed tweaking, awful brain fog, hair loss, brittle peeling ridged nails, cold feet but extreme sweating at times incl night sweats, dry flaky skin, horrible joint
Vorney
in
Thyroid UK
8 months ago
ADT working mechanism
I was just wondering, I heard dr. Richard Joel Wassersug Saying that ADT works well and better if you continue with it but if you start and stop, start and stop, it doesn’t work as well. Did all of you from your own experiences found this to be the case based on your experiences? Thanks for any feedback
I was just wondering, I heard dr. Richard Joel Wassersug Saying that ADT works well and better if you continue with it but if you start and stop, start and stop, it doesn’t work as well. Did all of you from your own experiences found this to be the case based on your experiences? Thanks for any feedback
Ahk1
in
Advanced Prostate Cancer
8 months ago
restricted urinary flow
Finished IMRT/ SBRT radiation to lymph nodes last week. Since then Ive begun have early AM restricted urinary flow - Very narrow stream. Rad Onc suggested tamsulosin or ibuprophen. MO, tamsulosin. Any work around for the early AM problem that I could take overnight? Ibuprophen has to be taken all
Finished IMRT/ SBRT radiation to lymph nodes last week. Since then Ive begun have early AM restricted urinary flow - Very narrow stream. Rad Onc suggested tamsulosin or ibuprophen. MO, tamsulosin. Any work around for the early AM problem that I could take overnight? Ibuprophen has to be taken all
kainasar
in
Fight Prostate Cancer
7 months ago
thrombotic thrombocytopenic purpura (TTP)
Warriors: Recently, I posted about 1 year side effects. Thank you for all of your responses. My SEs got the best of me and I’m writing from a hospital bed. The current theory is I have TTP, which is associated with hormonal therapy. I wanted to write and see if any of you have had the misfortune
Warriors: Recently, I posted about 1 year side effects. Thank you for all of your responses. My SEs got the best of me and I’m writing from a hospital bed. The current theory is I have TTP, which is associated with hormonal therapy. I wanted to write and see if any of you have had the misfortune
TMcgee
in
Advanced Prostate Cancer
8 months ago
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