Experiences with

Salvage therapy

hello all. Well my last two ( three month) PSA tests were 0.10 and MO. And RO. Recommend somewhat early salvage radiation treatment. A question I would like some input on is should I look into proton therapy over IMRT. I would need to travel to Fred hutch or Salt Lake City as I live in Reno Nv. Just

If we end up going down that road here is a recent paper on it. https://www.auajournals.org/doi/10.1097/JU.0000000000003890 (Post RT) Post RP https://www.auajournals.org/doi/10.1097/JU.0000000000003892 https://www.auajournals.org/doi/10.1097/JU.0000000000003891

https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival.

(2) Are the side effects of salvage radiation therapy the same as if radiation was the initial treatment option? (3) What is the SOC for salvage hormone therapy (that is combined with salvage radiation) after RP? How long do you need to take hormones for?

I underwent 35 sessions (70 Gy) of IMRT salvage radiation therapy (SRT) to my prostate bed only in July and August 2022. Now, 27 months after the radiation ended, I am seeing traces of blood in my stools about 10% of the time. There were a couple of instances where the spots were more noticeable.

ART= adjuvant radiation therapy, within 6 months after radical prostatectomy (RP) early SRT= salvage radiation therapy, after PSA ≥ 0.1ng/ml or 3 consecutive rises. Median was 0.2 ng/ml. Median 1 ½ years after RP.

I had a radical prostatectomy in 2021 followed by salvage radio therapy. My psa levels have been rising slowly since then and I wondered if there was any advice as to what it might mean and if there is anything I should be doing at this point?

And Salvage Therapy also in his case. No need to overtreat him. But should he not have hormones?! Anyone with similar experience? Just waiting and not knowing is so hard on us. I am soo close my dad and just gave birth the same time that he had his surgery.

The study found that [i]patients who received radiation therapy at PSA levels higher than 0.25 ng/mL had a 49% increase in all-cause mortality risk[/i] (95% CI 1.11-2.00, P=0.008).

And Salvage Therapy also in his case. No need to overtreat him. But should he not have hormones?! Anyone with similar experience? Just waiting and not knowing is so hard on us.I am soo close my dad and just gave birth the same time that he had his surgery.

Hello All I just completed the second BT procedure at MSK. Pain level was maybe 3 but mostly gone the next morning with some soreness. My next step I’m told is bloodwork in 3 months which I’m not concerned about. I am concerned about the 6 month MRI which could show if any cancer still remains. When

His MO wanted to see the third month's results in order to consider salvage radiation therapy. Luckily, third month's result came in at 0.012. Is it normal for PSA to fluctuate that much, from 0.006 to 0.029, then 0.012? Could this be a lab error? All tests were done at the same lab.

With prostate gone, it seems a higher portion of the bladder and rectum will be in the radiation target area when it comes to salvage therapy, and hence causing more side effects.

In the absence of salvage therapy (sRT), the median time from PSA recurrence to distant metastasis is 8 years. 2.

After surgery and salvage radiation therapy (SRT) have failed, it appears I'm headed for androgen deprivation therapy.

I had a radical prostatectomy that failed and then salvage radiation therapy that appears to have failed as well. A recent PSMA PET scan showed no signs of recurrent prostate cancer or metastases.

The AMPLITUDE clinical trial (NCT04497844) is evaluating the effectiveness of Akeega, a combination of the PARP inhibitor niraparib and abiraterone acetate, along with prednisone, for treating metastatic castration-sensitive prostate cancer (mCSPC). This combination therapy is being compared to the

A new research from Oslo University focuses on a new combination therapy for prostate cancer that uses a checkpoint inhibitor and an IRE1 blocker called MKC8866. The therapy works by blocking the IRE1 signaling pathway, which in turn reduces immunosuppressive effects in the tumor microenvironment and

Anyone seen this? This is what JSBMD is talking about https://pmc.ncbi.nlm.nih.gov/articles/PMC11083272/#sec6-ijms-25-04643 Conclusions TH inhibitors down-regulate DA levels and protect DA neurons, while DA receptor agonists function to activate post-synaptic DA receptors to alleviate PD symptoms

Can this be treated with targeted therapy such as Herceptin ( I am not aware of the presence of HER 2 ) but have been told that the surgical option would kill my husband who is 75 yrs old even though CT scan shows no spread . He has not had a PET scan.