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Only mouse study, but interesting research on microbiome using astragaloside and scorpion venom
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathwayXujun You, Junfeng Qiu, Qixin Li, Qing Zhang, Wen Sheng, Yiguo Cao, Wei Fu BMC cancer 24 (1), 472, 2024 Background Prostate cancer (PCa) is becoming the
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathwayXujun You, Junfeng Qiu, Qixin Li, Qing Zhang, Wen Sheng, Yiguo Cao, Wei Fu BMC cancer 24 (1), 472, 2024 Background Prostate cancer (PCa) is becoming the
Graham49
in
Advanced Prostate Cancer
2 months ago
Strange definition of pernicious anemia
Found this questionable definition of pernicious anemia on a Johns Hopkins web page about gastritis: [i]
Pernicious anemia
. This is a form of anemia that happens when your stomach can't digest vitamin B-12.[/i] Even the best seem to get it wrong. https://www.hopkinsmedicine.org/health/conditions-and-diseases
Found this questionable definition of pernicious anemia on a Johns Hopkins web page about gastritis: [i]
Pernicious anemia
. This is a form of anemia that happens when your stomach can't digest vitamin B-12.[/i] Even the best seem to get it wrong. https://www.hopkinsmedicine.org/health/conditions-and-diseases
palmier
in
Pernicious Anaemia Society
2 months ago
Serum parathyroid hormone
Finally, after a year of the labs refusing to test Vit D, I finally had it tested, and as suspected, it was below the bottom of the scale - 23. So back on tablets and spray, and hopefully my leg muscles will start working again... The lab refusing to test has made me ill...grumble, grumble. Anyway
Finally, after a year of the labs refusing to test Vit D, I finally had it tested, and as suspected, it was below the bottom of the scale - 23. So back on tablets and spray, and hopefully my leg muscles will start working again... The lab refusing to test has made me ill...grumble, grumble. Anyway
serenfach
in
Thyroid UK
2 months ago
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Clotting
Since taking over my PA treatment with frequent injections, my symptoms have greatly ameliorated. However, there's one thing I hadn't anticipated. Recently I've had to have a couple of teeth extracted. Each time I've ended up in casualty because the bleeding wouldn't stop, and wondered about B12.
Since taking over my PA treatment with frequent injections, my symptoms have greatly ameliorated. However, there's one thing I hadn't anticipated. Recently I've had to have a couple of teeth extracted. Each time I've ended up in casualty because the bleeding wouldn't stop, and wondered about B12.
tomdickharry
in
Pernicious Anaemia Society
2 months ago
Confusing biopsy results
I was diagnosed with PA early 2023 after years of feeling hopeless and helpless, ( raised MCV , low 'normal' serum B12, positive Parietal Cell antibodies, no intrinsic factor antibodies) and I am SI B12 regularly, to which I am responding well, and finally starting to feel like I am coming out the
I was diagnosed with PA early 2023 after years of feeling hopeless and helpless, ( raised MCV , low 'normal' serum B12, positive Parietal Cell antibodies, no intrinsic factor antibodies) and I am SI B12 regularly, to which I am responding well, and finally starting to feel like I am coming out the
DiSews
in
Pernicious Anaemia Society
2 months ago
Cramp plus update
Hi everyone- just thought I would do an update on where I am at the moment. For the first time ever I am on my way down from 3mg to 2 and three quarter mg , never made it this far before without a flare. Very happy about that. I have also gradually stopped using Lansoprazole after 6.5 years. I went
Hi everyone- just thought I would do an update on where I am at the moment. For the first time ever I am on my way down from 3mg to 2 and three quarter mg , never made it this far before without a flare. Very happy about that. I have also gradually stopped using Lansoprazole after 6.5 years. I went
Purplegloss
in
PMRGCAuk
2 months ago
Teenager daughter in total denial of diagnosis
My 15 year old daughter got diagnosed with ADHD Inattentive type this spring and summer by two different doctors. First through some cognitive testing (where mild dyslexia was also diagnosed) and secondly through a psychiatrist. For us the diagnosis was almost a relieve, as a lot of things started to
My 15 year old daughter got diagnosed with ADHD Inattentive type this spring and summer by two different doctors. First through some cognitive testing (where mild dyslexia was also diagnosed) and secondly through a psychiatrist. For us the diagnosis was almost a relieve, as a lot of things started to
Westcoast2023
in
CHADD's ADHD Parents Together
11 months ago
Started Interferon
About two weeks ago I put a post on here about my anxiety around changing my treatment plan from Hydroxy to Peg Interferon. I had been sent the vaccine but not given any specific instruction about how to self inject. I appreciated the advice I was given from others who had trodden this path before
About two weeks ago I put a post on here about my anxiety around changing my treatment plan from Hydroxy to Peg Interferon. I had been sent the vaccine but not given any specific instruction about how to self inject. I appreciated the advice I was given from others who had trodden this path before
Reggieroo
in
MPN Voice
2 months ago
Just unbelievable
Helen's Hashi's Journey continues: History: has a HO hashimotos, and long HO feeling TATT, Sleep is poor, as soon as she lies down get fullness in head and ears this causes poor sleep, No snoring, but wakes with dry mouth and has nasal congestion. Examination: throat NAD- no uvula, chest clar, 95
Helen's Hashi's Journey continues: History: has a HO hashimotos, and long HO feeling TATT, Sleep is poor, as soon as she lies down get fullness in head and ears this causes poor sleep, No snoring, but wakes with dry mouth and has nasal congestion. Examination: throat NAD- no uvula, chest clar, 95
helenshubby
in
Thyroid UK
2 months ago
Peptic Liquid/ Gaviscon & B12 Injections
Hello! I was diagnosed with low B12 at the end of last year and on 3 monthly injections at my GP surgery… following a visit to my ENT consultant for ongoing ear issues and horrendous hay fever, he diagnosed me with silent reflux and suggested Gaviscon.. my question is, when I have my B12 injection would
Hello! I was diagnosed with low B12 at the end of last year and on 3 monthly injections at my GP surgery… following a visit to my ENT consultant for ongoing ear issues and horrendous hay fever, he diagnosed me with silent reflux and suggested Gaviscon.. my question is, when I have my B12 injection would
Hidden
in
Pernicious Anaemia Society
2 months ago
My RLS has settled for the time being. Thank you for the information and support!
For the past six months, I've been RLS free! I'm so happy about this and it has made such a difference to my sleep and wellbeing. I have the wonderful, supportive people on here to thank, and especially SueJohnson. Because I received such a good amount of information last year, I was able to check
For the past six months, I've been RLS free! I'm so happy about this and it has made such a difference to my sleep and wellbeing. I have the wonderful, supportive people on here to thank, and especially SueJohnson. Because I received such a good amount of information last year, I was able to check
SummerDark
in
Restless Legs Syndrome
2 months ago
More on D3 supplementation (only if you're really into it)
This may be a bit boring, as well as off-topic; but I was curious; so I looked up a bit more on how much to supplement vitamin D, so as to get the benefits and still be on the safe side.
What's recommended?
In the U.S., the NIH (National Institutes of Health) advises "consumers" to aim for
This may be a bit boring, as well as off-topic; but I was curious; so I looked up a bit more on how much to supplement vitamin D, so as to get the benefits and still be on the safe side.
What's recommended?
In the U.S., the NIH (National Institutes of Health) advises "consumers" to aim for
UsableThought
in
Restless Legs Syndrome
2 months ago
latest bloods ahead of neurology appt tomoz advice needed
hi all Just got my latest bloods is ahead of my neurology appt tomoz and am looking for advice Serum ferritin - 37 down from 54 Serum folate >20 Serum magnesium 0.91 Platelets 120 mine are usually low Serum iron level 16 Transferrin 2.3 I’ve also got low calcium at 2.09 And High anticardiolipin
hi all Just got my latest bloods is ahead of my neurology appt tomoz and am looking for advice Serum ferritin - 37 down from 54 Serum folate >20 Serum magnesium 0.91 Platelets 120 mine are usually low Serum iron level 16 Transferrin 2.3 I’ve also got low calcium at 2.09 And High anticardiolipin
Zenawarrior73
in
Restless Legs Syndrome
2 months ago
How soon can I re-test folate levels?
After getting a low folate blood test, I have changed my diet to greatly increase folate intake (can't tolerate any folate supplement). How soon can I take another blood test to see if my levels have come up? It has been 3 weeks since I changed my diet.
After getting a low folate blood test, I have changed my diet to greatly increase folate intake (can't tolerate any folate supplement). How soon can I take another blood test to see if my levels have come up? It has been 3 weeks since I changed my diet.
Carrie234
in
Thyroid UK
2 months ago
Looking for vitamin C infusions in Perth, Western Australia without glutathione?
Dear all Vitamin C infusions were tremendously helpful for my Dad in 2017 when he was diagnosed with metastatic prostate cancer and underwent a prostatectomy, chemotherapy and radiotherapy. Now trying to find them again. Those I have found include glutathione which I think is not good with cancer.
Dear all Vitamin C infusions were tremendously helpful for my Dad in 2017 when he was diagnosed with metastatic prostate cancer and underwent a prostatectomy, chemotherapy and radiotherapy. Now trying to find them again. Those I have found include glutathione which I think is not good with cancer.
TomsD1
in
Advanced Prostate Cancer
2 months ago
Follow up results
Hi TiggerMe Here are the results that I said I would post. NHS 21 June 8 am, fasted, no levo for 24 hrs, stopped b complex 6 days before. TSH: 1.12 (0.27-4.2) 21.6% T4: 17.5 (12-22) 55% T3: 4.6 (3.1-6.8) 40.4% Serum Vit D: 69nmol/L (50-300) >50 adequate Serum Ferritin: 54ng/ml (30-150) Serum
Hi TiggerMe Here are the results that I said I would post. NHS 21 June 8 am, fasted, no levo for 24 hrs, stopped b complex 6 days before. TSH: 1.12 (0.27-4.2) 21.6% T4: 17.5 (12-22) 55% T3: 4.6 (3.1-6.8) 40.4% Serum Vit D: 69nmol/L (50-300) >50 adequate Serum Ferritin: 54ng/ml (30-150) Serum
pastashapes
in
Thyroid UK
2 months ago
Compensated Cirrhosis - Sudden Extreme Increase in Liver Stiffness - Under Treatment, Blood Tests Normalized
During annual medical tests in Feb 2024: - Saw elevated Liver Enzymes, Hi bilirubinFibroscan (ordered by Dr) Stage 2 Fatty Liver, LSM 12.59, Early eosphageal varices, normal platelets (low end of normal) - Compensated Child-A Cirrhosis - Diabetic, high Cholesterol, hi triglycerides Hypertension: All
During annual medical tests in Feb 2024: - Saw elevated Liver Enzymes, Hi bilirubinFibroscan (ordered by Dr) Stage 2 Fatty Liver, LSM 12.59, Early eosphageal varices, normal platelets (low end of normal) - Compensated Child-A Cirrhosis - Diabetic, high Cholesterol, hi triglycerides Hypertension: All
ZeroInfiniti
in
British Liver Trust
2 months ago
Compensated Cirrhosis - Sudden Extreme Increase in Liver Stiffness while Blood Reports Have become Normal
During annual medical tests in Feb 2024: - Saw elevated Liver Enzymes, Hi bilirubinFibroscan (ordered by Dr) Stage 2 Fatty Liver, LSM 12.8, Early eosphageal varices, normal platelets (low end of normal) - Compensated Child-A Cirrhosis - Diabetic, high Cholesterol, hi triglycerides Hypertension: All
During annual medical tests in Feb 2024: - Saw elevated Liver Enzymes, Hi bilirubinFibroscan (ordered by Dr) Stage 2 Fatty Liver, LSM 12.8, Early eosphageal varices, normal platelets (low end of normal) - Compensated Child-A Cirrhosis - Diabetic, high Cholesterol, hi triglycerides Hypertension: All
ZeroInfiniti
in
Living with Fatty Liver and NASH
2 months ago
Painful indigestion
I have pernicious anaemia treated with vit b12 injections. Prior to being diagnosed I suffered with terrible indigestion and the usual meds, like gaviscon, windeze, omprezole did nothing to alleviate it. Since starting the b12 injections the indigestion is less frequent but still very painful and wakes
I have pernicious anaemia treated with vit b12 injections. Prior to being diagnosed I suffered with terrible indigestion and the usual meds, like gaviscon, windeze, omprezole did nothing to alleviate it. Since starting the b12 injections the indigestion is less frequent but still very painful and wakes
Kangarooiom
in
Pernicious Anaemia Society
2 months ago
Advice re levothyroxine dosage
HelloI would be very greatful for advice regarding my next move re Levothyroxine dosage. On 10 May 2024 began 100mcg levothyroxine after titrating up following blood tests and still experiencing symptoms since Jan 24. Did finger prick test on 20 June (test taken at 7.30 am, fasted and no levo 24 hours
HelloI would be very greatful for advice regarding my next move re Levothyroxine dosage. On 10 May 2024 began 100mcg levothyroxine after titrating up following blood tests and still experiencing symptoms since Jan 24. Did finger prick test on 20 June (test taken at 7.30 am, fasted and no levo 24 hours
pastashapes
in
Thyroid UK
2 months ago
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