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Prostate-specific antigen (PSA)
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A question about radiation resistance
(such as
PSA
drops, but not significantly) I did have PSMA immediately prior to SBRT that only showed
PSA
at site of lesion.
(such as
PSA
drops, but not significantly) I did have PSMA immediately prior to SBRT that only showed
PSA
at site of lesion.
Chasbearcat999
in
Prostate Cancer Network
19 days ago
Rising PSA
I'm Poollover, Just got the results of a blood test and my
PSA
went up from 0.67 to 0.77. I'm on Orgovyx and Zytiga. I'm 86 years old. How concerned should I be? 8 months ago it was about 12. That was before medication. Also slightly anemic. What are my options? Terry
I'm Poollover, Just got the results of a blood test and my
PSA
went up from 0.67 to 0.77. I'm on Orgovyx and Zytiga. I'm 86 years old. How concerned should I be? 8 months ago it was about 12. That was before medication. Also slightly anemic. What are my options? Terry
Poollover
in
Advanced Prostate Cancer
3 months ago
PCa doctors in Phoenix area?
My friend has
PSA
of 9.3. Last
PSA
was in mid 1's. Lives in Phoenix area. Was treated for frequent urination with Flomax in the past,, but hasn't been on it for a long time. Any recommendations for doctor for initial consultation? Thanks
My friend has
PSA
of 9.3. Last
PSA
was in mid 1's. Lives in Phoenix area. Was treated for frequent urination with Flomax in the past,, but hasn't been on it for a long time. Any recommendations for doctor for initial consultation? Thanks
Piano777
in
Prostate Cancer Network
9 days ago
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Mikemike
Metastices showed up 14 most later...
PSA
6.7 up to 16.2 in 6 weeks. PSMA pet showed two rib mets and 1 other on the pubic ramus. Radiated all at Mayo/Jax...
psa
16.2...down to 7...last
PSA
earlier this week two 4.9. What else can I help you with? Prostatectomy OR radiation?
Metastices showed up 14 most later...
PSA
6.7 up to 16.2 in 6 weeks. PSMA pet showed two rib mets and 1 other on the pubic ramus. Radiated all at Mayo/Jax...
psa
16.2...down to 7...last
PSA
earlier this week two 4.9. What else can I help you with? Prostatectomy OR radiation?
Poppy1952
in
Advanced Prostate Cancer
11 days ago
Failed RP & SRT; Negative PSMA PET
biochemical recurrence threshold at 0.21 ng/mL NOV 2021 - PSMA PET scan with
PSA
at 0.22 ng/mL; no signs of cancer MAY 2022 - Six-month dose of Eligard in advance of SRT;
PSA
at 0.36 ng/mL JUL-AUG 2022 - 35 sessions of IMRT to prostate bed only MAR 2023 -
PSA
0.13 ng/mL MAY 2023 -
PSA
0.11 ng/mL
biochemical recurrence threshold at 0.21 ng/mL NOV 2021 - PSMA PET scan with
PSA
at 0.22 ng/mL; no signs of cancer MAY 2022 - Six-month dose of Eligard in advance of SRT;
PSA
at 0.36 ng/mL JUL-AUG 2022 - 35 sessions of IMRT to prostate bed only MAR 2023 -
PSA
0.13 ng/mL MAY 2023 -
PSA
0.11 ng/mL
dans_journey
in
Advanced Prostate Cancer
4 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own
PSA
values versus time plot. You can see there is an exponential rise in
PSA
starting at around 6/1/23, and doubling from
PSA
= 5 to 10 in about 8 months. My MRI at
PSA
= 10 showed a T3a tumor about 1.3 cm long (PIRADS 5).
Here are my own
PSA
values versus time plot. You can see there is an exponential rise in
PSA
starting at around 6/1/23, and doubling from
PSA
= 5 to 10 in about 8 months. My MRI at
PSA
= 10 showed a T3a tumor about 1.3 cm long (PIRADS 5).
janebob99
in
Prostate Cancer Network
3 months ago
Studies re: PSA > 0.5% after RT
prostate-cancer/even-low-
psa
-levels-after-rt-adt-can-predict-prostate-cancer-outcomes/ https://dailynews.ascopubs.org/do/
psa
-nadir-6-months-after-radiotherapy-strongly-prognostic-long-term-survival-patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429233/
prostate-cancer/even-low-
psa
-levels-after-rt-adt-can-predict-prostate-cancer-outcomes/ https://dailynews.ascopubs.org/do/
psa
-nadir-6-months-after-radiotherapy-strongly-prognostic-long-term-survival-patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429233/
quietcorner
in
Advanced Prostate Cancer
2 months ago
Erleada or Xtandi with Orgovyx, preference one way or the other?
PSA
5.4 started Orgovyx along with Xtandi for 12 months of 2023, vacation from 01/24 thru 05/24
PSA
back to 4.8 along with new mets along with worsening former mets. 2023 Orgovyx/Xtandi combo dropped
PSA
to non detectable in 3 months.
PSA
5.4 started Orgovyx along with Xtandi for 12 months of 2023, vacation from 01/24 thru 05/24
PSA
back to 4.8 along with new mets along with worsening former mets. 2023 Orgovyx/Xtandi combo dropped
PSA
to non detectable in 3 months.
Wynnsts
in
Advanced Prostate Cancer
3 days ago
Pluvicto still working well
So far: Aug 16:
PSA
99.7
Aug 21: Pluvicto
#1
Sep 11:
PSA
106
Sep 28:
PSA
91.8
Oct 05: Pluvicto
#2
Oct 25:
PSA
57.8
Nov 09:
PSA
47.4
Nov 16: Pluvicto
#3
Dec 06:
PSA
31.8
Dec 28:
PSA
26.5[/
So far: Aug 16:
PSA
99.7
Aug 21: Pluvicto
#1
Sep 11:
PSA
106
Sep 28:
PSA
91.8
Oct 05: Pluvicto
#2
Oct 25:
PSA
57.8
Nov 09:
PSA
47.4
Nov 16: Pluvicto
#3
Dec 06:
PSA
31.8
Dec 28:
PSA
26.5[/
Miccoman
in
Advanced Prostate Cancer
4 months ago
Rising PSA
In one year
PSA
has been rising. Up to 14 now. Dr. Aggarwal says no longer treat
PSA
# only scan results. Yet, CT with contrast is not definitive. Thoughts? Thank you!
In one year
PSA
has been rising. Up to 14 now. Dr. Aggarwal says no longer treat
PSA
# only scan results. Yet, CT with contrast is not definitive. Thoughts? Thank you!
JolleySprings
in
Advanced Prostate Cancer
3 months ago
PSA uptick
His
PSA
has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning signal. Other labs are stable and bone scan a few months ago was stable.
His
PSA
has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning signal. Other labs are stable and bone scan a few months ago was stable.
mediocra
in
Advanced Prostate Cancer
3 months ago
Cause for concern?
Ignorant/lazy docs only take notice of the
PSA
, when it is widely known that at low
PSA
PSADT is equally, if not more an important factor, for estimating the probability of a positive PSMA PET/CT detection. With your PSADT of 5 months.....................
Ignorant/lazy docs only take notice of the
PSA
, when it is widely known that at low
PSA
PSADT is equally, if not more an important factor, for estimating the probability of a positive PSMA PET/CT detection. With your PSADT of 5 months.....................
m1946
in
Prostate Cancer Network
2 months ago
Appropriate Treatment
I was diagnosed with stage 4 prostate cancer
PSA
29.1 which had metastatised to lymph nodes, ribs & spine after a few months on Abiraterone and Prednisone my
PSA
count dropped to 0.06 After 30 months my
PSA
started to rise at 10.2 my treatment was declared ineffective Lutetium 177 treatment was recommended
I was diagnosed with stage 4 prostate cancer
PSA
29.1 which had metastatised to lymph nodes, ribs & spine after a few months on Abiraterone and Prednisone my
PSA
count dropped to 0.06 After 30 months my
PSA
started to rise at 10.2 my treatment was declared ineffective Lutetium 177 treatment was recommended
154Eleventh
in
Advanced Prostate Cancer
1 month ago
improving!
My
PSA
reading a few months ago was 1900+. it had been rising constantly for three years. Then I started taking Fenbendazole tablets for three days each week, and my
PSA
reading dropped by 400 each month and it is now 800+ and hopefully continuing to reduce! Mobellman
My
PSA
reading a few months ago was 1900+. it had been rising constantly for three years. Then I started taking Fenbendazole tablets for three days each week, and my
PSA
reading dropped by 400 each month and it is now 800+ and hopefully continuing to reduce! Mobellman
Mobellman
in
Advanced Prostate Cancer
20 days ago
Time to PSA Nadir is related to progression-free-survival
Initiation of any secondary hormone treatment for rising
PSA
also was considered as a progression event."[/i] What is interesting and unexpected is the "Third Phase" (where the Time to
PSA
Nadir is greater than 17 months).
Initiation of any secondary hormone treatment for rising
PSA
also was considered as a progression event."[/i] What is interesting and unexpected is the "Third Phase" (where the Time to
PSA
Nadir is greater than 17 months).
janebob99
in
Advanced Prostate Cancer
2 months ago
Uh... Oh... New Phase Awaits?
Worked well so was able to stop...BUT NOW Starting to look like castrate resistance: 9/14/23
PSA
= 0.26 Total T = 41 11/28/23
PSA
= 1.2 Total T = 51 1/15/24
PSA
= 1.7 Total T = 64 3/18/24
PSA
= 2.6 Total T = 56 We are going to do 1 more in 2 months. Then ? Am I castrate resistant?
Worked well so was able to stop...BUT NOW Starting to look like castrate resistance: 9/14/23
PSA
= 0.26 Total T = 41 11/28/23
PSA
= 1.2 Total T = 51 1/15/24
PSA
= 1.7 Total T = 64 3/18/24
PSA
= 2.6 Total T = 56 We are going to do 1 more in 2 months. Then ? Am I castrate resistant?
compiler
in
Advanced Prostate Cancer
2 months ago
PSA rise
2 months ago my
PSA
was 20. I have had extensive screening done prior to starting a clinical trial on Tuesday. My
PSA
has gone up to 367 since then. CT scan showed no significant change and I had bone scan yesterday.
2 months ago my
PSA
was 20. I have had extensive screening done prior to starting a clinical trial on Tuesday. My
PSA
has gone up to 367 since then. CT scan showed no significant change and I had bone scan yesterday.
konichiwa12
in
Advanced Prostate Cancer
3 months ago
Getting head around what to expect
May 2023,
PSA
<.05 , November 2023
PSA
<.05, May 2024
PSA
1.6. current age 58, otherwise healthy and in great shape. Next steps: Verification
PSA
scheduled for June 10 2024, MSK says to expect Radiation.
May 2023,
PSA
<.05 , November 2023
PSA
<.05, May 2024
PSA
1.6. current age 58, otherwise healthy and in great shape. Next steps: Verification
PSA
scheduled for June 10 2024, MSK says to expect Radiation.
Melzer2169
in
Advanced Prostate Cancer
17 days ago
Small psa rise
PSA
less 0.01 consistently until last week 0.03. Do I need to wait until
PSA
is 2.0 or is there anything I can do before then?
PSA
less 0.01 consistently until last week 0.03. Do I need to wait until
PSA
is 2.0 or is there anything I can do before then?
Runner1957
in
Prostate Cancer Network
12 days ago
PSA update
PSA
960 high volume metastatic. Lowest
PSA
nadir 0.1 Aug 2022. Slowly rising Nov. 2023 was 0.21, Feb 2024 0.41....Doubling time 3.1 months . On Lupron and 1000 mg Abiraterone with 0.5 Dexamethasone . Darn.
PSA
960 high volume metastatic. Lowest
PSA
nadir 0.1 Aug 2022. Slowly rising Nov. 2023 was 0.21, Feb 2024 0.41....Doubling time 3.1 months . On Lupron and 1000 mg Abiraterone with 0.5 Dexamethasone . Darn.
wolverine11
in
Advanced Prostate Cancer
4 months ago
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