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Concern - At 4 mo on Lupron/Abi, Testosterone hits 40
While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested
While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested
jackwfrench
in
Advanced Prostate Cancer
8 months ago
Testosterone increase after injection
I recently had my 6 month dose of Camcevi 42mg and my testosterone went from 7 t0 55 rights after the injection. My PSA remained the same at 0.1 . Is this normal for my testosterone to jump 48 points. Oncologist says he is more concerned with my PSA. Also the injection of the Camcevi was in my lower
I recently had my 6 month dose of Camcevi 42mg and my testosterone went from 7 t0 55 rights after the injection. My PSA remained the same at 0.1 . Is this normal for my testosterone to jump 48 points. Oncologist says he is more concerned with my PSA. Also the injection of the Camcevi was in my lower
Shadoz
in
Advanced Prostate Cancer
8 months ago
RT results look good
After a bout of sepsis from a directed biopsy, 5 weeks of RT and 3 months of Eligard, my tests show undetectable PSA. I'm still dealing with side effects (interrupted sleep, urinary and bowel differences) but happy to report it looks like, for the time being, that my stage 2/3 PC may have been beaten
After a bout of sepsis from a directed biopsy, 5 weeks of RT and 3 months of Eligard, my tests show undetectable PSA. I'm still dealing with side effects (interrupted sleep, urinary and bowel differences) but happy to report it looks like, for the time being, that my stage 2/3 PC may have been beaten
Eadgbe
in
Fight Prostate Cancer
8 months ago
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PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
8 months ago
PSA Roller Coaster ride!
Back a couple days ago, I posted a question about my PSA being undectable since July 2022. (<0.01) then this month is up to 2.22. I asked what is next etc. I had an appointment with my MO on 19 Dec 2023, they generally do lab work at the cancer center before they give me lupron. I ask them if
Back a couple days ago, I posted a question about my PSA being undectable since July 2022. (<0.01) then this month is up to 2.22. I asked what is next etc. I had an appointment with my MO on 19 Dec 2023, they generally do lab work at the cancer center before they give me lupron. I ask them if
JD-guy
in
Advanced Prostate Cancer
8 months ago
LIQUID BIOPSY: Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ?
Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ? Depending on the results do we get access to some novel drugs like olapariv or nivolumab, etc, that might help us ? đ« thanks, Manilo.
Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ? Depending on the results do we get access to some novel drugs like olapariv or nivolumab, etc, that might help us ? đ« thanks, Manilo.
Manilo
in
Advanced Prostate Cancer
8 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
Teddy28
in
Advanced Prostate Cancer
8 months ago
QoLing on a Prayer - a year later & PSA update
https://youtu.be/oabJ6vvz0OI?si=0gy0804F3Yqkp30s It's been a year since the 14th of 28s IMRT and the PSA is https://youtu.be/J2VDEl18rgQ?si=396vEID1xVZAw8S2 and at 1.3 the last two tests đ, the lowest in 5 years -Woo Hoo For anyone who missed the vid, here ya go: https://photos.app.goo.gl/NkXaWGSHiNYNmvM57
https://youtu.be/oabJ6vvz0OI?si=0gy0804F3Yqkp30s It's been a year since the 14th of 28s IMRT and the PSA is https://youtu.be/J2VDEl18rgQ?si=396vEID1xVZAw8S2 and at 1.3 the last two tests đ, the lowest in 5 years -Woo Hoo For anyone who missed the vid, here ya go: https://photos.app.goo.gl/NkXaWGSHiNYNmvM57
dockam
in
Advanced Prostate Cancer
5 months ago
R223 - PSA 26 Doubled since February
My husband has had 3 treatments of R223, had to postpone 4th treatment because of flu. On Monday had bloods taken in preparation of 4th treatment on 18th April 2024. Blood results ALP 76, at started of R223 106, HB 92 down from 102, (has Proctitis and occasional bleed, calcium a little low, taken
My husband has had 3 treatments of R223, had to postpone 4th treatment because of flu. On Monday had bloods taken in preparation of 4th treatment on 18th April 2024. Blood results ALP 76, at started of R223 106, HB 92 down from 102, (has Proctitis and occasional bleed, calcium a little low, taken
Janhpr
in
Advanced Prostate Cancer
5 months ago
Pfizer and Astellas' XTANDIÂź Approved by U.S. FDA in Earlier Prostate Cancer Treatment Setting
https://www.prnewswire.com/news-releases/pfizer-and-astellas-xtandi-approved-by-us-fda-in-earlier-prostate-cancer-treatment-setting-301991574.html
https://www.prnewswire.com/news-releases/pfizer-and-astellas-xtandi-approved-by-us-fda-in-earlier-prostate-cancer-treatment-setting-301991574.html
Maxone73
in
Advanced Prostate Cancer
9 months ago
Urinary incontinence in mCRPC
I am looking for help for my 81-year-old father who is mCRPC. He was diagnosed at stage 4 about 18 months ago with mets to 8+ bones including the skull. Summary of the following treatments: Bicalutamide this drug failed in July 2023 and the patient transitioned to Xtandi started in September 2023.
I am looking for help for my 81-year-old father who is mCRPC. He was diagnosed at stage 4 about 18 months ago with mets to 8+ bones including the skull. Summary of the following treatments: Bicalutamide this drug failed in July 2023 and the patient transitioned to Xtandi started in September 2023.
lgutman
in
Advanced Prostate Cancer
5 months ago
Constipation is a known issue with the Orgovyx
I've been on Orgovyx (Relugolix) for around 2.5 years now. and find myself getting increasingly constipated. It's the most tenacious SE. My labs are all stable and my PSA is stable at <0.02. But I'm now on 4 types of laxatives and next am planning on getting an enema and trying that. I have an appt with
I've been on Orgovyx (Relugolix) for around 2.5 years now. and find myself getting increasingly constipated. It's the most tenacious SE. My labs are all stable and my PSA is stable at <0.02. But I'm now on 4 types of laxatives and next am planning on getting an enema and trying that. I have an appt with
NewPotatoCaboose
in
Advanced Prostate Cancer
5 months ago
Rickyfish56 "Introduction"
Reviewed my "Bio" and it said I needed to "introduce" myself? Mostly just read postings and try to gather information. But, here is my " introduction", family history of Prostate cancer, Dad diagnosed at 59, removed prostate old fashion slice and dice, never regained any sexual function, but alive today
Reviewed my "Bio" and it said I needed to "introduce" myself? Mostly just read postings and try to gather information. But, here is my " introduction", family history of Prostate cancer, Dad diagnosed at 59, removed prostate old fashion slice and dice, never regained any sexual function, but alive today
rickyfish56
in
Advanced Prostate Cancer
8 months ago
Cancer return alert without scan or PSA ?
I'm more curious than anything to hear if you knew the cancer had returned somehow before any scan or blood test really told you? Pain? Bladder issues? Other signs ??? I'm wondering how many really knew somehow or sensed it and it was later confirmed ? Most people are very in-tuned to their own body
I'm more curious than anything to hear if you knew the cancer had returned somehow before any scan or blood test really told you? Pain? Bladder issues? Other signs ??? I'm wondering how many really knew somehow or sensed it and it was later confirmed ? Most people are very in-tuned to their own body
positive-thinking
in
Advanced Prostate Cancer
5 months ago
BONE DENSITY TEST IS BAD
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. thatâs the
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. thatâs the
JL1955
in
Advanced Prostate Cancer
8 months ago
Can Nubeqa (Darolutamide) be used instead of normal ADT drugs for localized PCa?
Hi all. Australia has just given the green light to lower the cost of this so-called wonder drug from a staggering $40K (AUD) to a low $30. It seems that this drug has fewer side effects than the usual ADT drugs and from what I can gather does a pretty good job of preventing the growth and spread
Hi all. Australia has just given the green light to lower the cost of this so-called wonder drug from a staggering $40K (AUD) to a low $30. It seems that this drug has fewer side effects than the usual ADT drugs and from what I can gather does a pretty good job of preventing the growth and spread
Mike58
in
Advanced Prostate Cancer
9 months ago
Nubeqa Vs Abiraterone
Which is more effective my PSA rising after being placed on Nubeqa. Prostate cancer metastasized to the bone
Which is more effective my PSA rising after being placed on Nubeqa. Prostate cancer metastasized to the bone
willie334
in
Advanced Prostate Cancer
8 months ago
CRISPR: hopes and research
I will keep you posted, also because it's a very fascinating technique that could potentially solve many health problems (and of course be used for evil...but that's not CRISPR fault, it's a fault in our brain!...which obviously CRISPR cannot fix!) "In addition, we also analyzed whether âi-CRISPRâ has
I will keep you posted, also because it's a very fascinating technique that could potentially solve many health problems (and of course be used for evil...but that's not CRISPR fault, it's a fault in our brain!...which obviously CRISPR cannot fix!) "In addition, we also analyzed whether âi-CRISPRâ has
Maxone73
in
Advanced Prostate Cancer
9 months ago
UK Cabazitaxel/Carboplatin availability
I have a fairly urgent decision to make regarding my treatment. For the benefit of our US warriors, the UK National Health Service means that the overwhelming majority of patients do not have private healthcare insurance. I'm one of those. Now, with the decision to switch from Docetaxel to Cabazataxel
I have a fairly urgent decision to make regarding my treatment. For the benefit of our US warriors, the UK National Health Service means that the overwhelming majority of patients do not have private healthcare insurance. I'm one of those. Now, with the decision to switch from Docetaxel to Cabazataxel
CrocodileShoes
in
Advanced Prostate Cancer
9 months ago
SOC & PSA
Three months post RT, my RO ordered a non-ultrasensitive PSA test with a lower limit of "<.1". I see posts of folks considering an increase from .02 to .06 a PSA doubling - obviously which would not be observable with my PSA test. This makes me wonder why: 1) Is there any good reason why an ultrasensitive
Three months post RT, my RO ordered a non-ultrasensitive PSA test with a lower limit of "<.1". I see posts of folks considering an increase from .02 to .06 a PSA doubling - obviously which would not be observable with my PSA test. This makes me wonder why: 1) Is there any good reason why an ultrasensitive
SCreader
in
Advanced Prostate Cancer
8 months ago
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