R223 - PSA 26 Doubled since February

[Janhpr]

My husband has had 3 treatments of R223, had to postpone 4th treatment because of flu.

On Monday had bloods taken in preparation of 4th treatment on 18th April 2024.

Blood results ALP 76, at started of R223 106, HB 92 down from 102, (has Proctitis and occasional bleed, calcium a little low, taken adcal twice a day, what is concerning is PSA 26, was 10.4 at start of R223 in December, told does flare with this treatment but once treatment stopped will come down, but is worrying, has little bone pain and quickly controlled with paracetamol.

Tinnitus has become a real issue, keeping my husband awake, I believe it might be stress related, seeing a Tinnitus specialist tomorrow, but understand no cure.

Another concern routine INR bloods done Tuesday INR 7, high, advised by INR nurse to stop Warfarin until Friday, further bloods on Friday hopefully down to lower reading. If had antibiotics may have gone as high as 4.6, but usually with regime of INR 2 - 3. On Warfarin as multi pulmonary embolism while having chemotherapy 2010.

We would be grateful of any thoughts or advice kind regards Jan & Tony

[GP24]

Ra223 usually does not lower the PSA value. That will rise while Ra223 works.

[Janhpr in reply to GP24]

thank you for your reply and explanation, reassuring

[God_Loves_Me]

I am NOT a Doctor. Here are my opinions, and I request that you discuss

with the doctor.

R223 will raise your PSA and It is not design to lower PSA. I understand that a PSA number is a way to track things.

Coordinate with MO, request multiple scans over six months, and track comparisons.

PSA will become unreliable numbers for the next couple of months..even one year

PSA is reporting dead cancer cells, too. That's the reason the number is not reliable anymore now.

[j-o-h-n]

Seeing Tinnitus specialist tomorrow, but understand no cure. Only way to beat it is by using your mind to ignore it..... DON'T THINK ABOUT IT!!! (Like thinking about your ex-spouse)....

Good Luck, Good Health and Good Humor.

j-o-h-n