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What is Tetrahydrobiopterin (BH4) and How Can I Make More of it?
Tetrahydrobiopterin (BH4, sometimes THB) is a vital cofactor for numerous enzymes in the body, including those involved in the formation of nitric oxide (NO), and the key neurotransmitters dopamine, serotonin and epinephrine. https://www.mygenefood.com/blog/tetrahydrobiopterin-bh4-can-make/
Tetrahydrobiopterin (BH4, sometimes THB) is a vital cofactor for numerous enzymes in the body, including those involved in the formation of nitric oxide (NO), and the key neurotransmitters dopamine, serotonin and epinephrine. https://www.mygenefood.com/blog/tetrahydrobiopterin-bh4-can-make/
Kia17
in
Cure Parkinson's
3 years ago
More Bee Stuff: Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster - 2020
http://idr.kab.ac.ug/bitstream/handle/20.500.12493/439/synergistic-action-of-propolis-with-levodopa-in-the-management-of-
parkinsonism
-indrosophila-.pdf?
http://idr.kab.ac.ug/bitstream/handle/20.500.12493/439/synergistic-action-of-propolis-with-levodopa-in-the-management-of-
parkinsonism
-indrosophila-.pdf?
Bolt_Upright
in
Cure Parkinson's
3 years ago
Update on CUE 1
I’ve been sent this for anyone following the progress of this little device. Do not ask me any questions about it! I only know what you can read here!... Dear All, As we prepare for our upcoming launch of the CUE1, we wanted to share with you just some of the updates from us and our community, and give
I’ve been sent this for anyone following the progress of this little device. Do not ask me any questions about it! I only know what you can read here!... Dear All, As we prepare for our upcoming launch of the CUE1, we wanted to share with you just some of the updates from us and our community, and give
Dap1948
in
Cure Parkinson's
3 years ago
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Melatonin: Regulation of Biomolecular Condensates in Neurodegenerative Disorders
https://www.mdpi.com/2076-3921/10/9/1483/htm chartist please help decipher Conclusions The physiological and pathological functions of biomolecular condensates in neurodegenerative disorders are shaped by powerful, complex, interdependent relationships between membraneless organelles, membranes/lipid
https://www.mdpi.com/2076-3921/10/9/1483/htm chartist please help decipher Conclusions The physiological and pathological functions of biomolecular condensates in neurodegenerative disorders are shaped by powerful, complex, interdependent relationships between membraneless organelles, membranes/lipid
JayPwP
in
Cure Parkinson's
3 years ago
Ketamine
Has anyone tried Ketamine for PD dyskinesia or depression associated with PD? There is a clinical trial opening in my area and I am trying to decide whether or not to participate. My dyskinesia is mild. Thanks!
Has anyone tried Ketamine for PD dyskinesia or depression associated with PD? There is a clinical trial opening in my area and I am trying to decide whether or not to participate. My dyskinesia is mild. Thanks!
Canddy
in
Cure Parkinson's
3 years ago
Find exercise for specific muscles
If you’re just starting out with strength training or the weight room is your second home, MuscleWiki can be a super-helpful tool. Pick a muscle from the interactive body map, and the website will show you to a list of moves (GIFs included!). We’re big fans of these easy-to-follow strength-training exercises
If you’re just starting out with strength training or the weight room is your second home, MuscleWiki can be a super-helpful tool. Pick a muscle from the interactive body map, and the website will show you to a list of moves (GIFs included!). We’re big fans of these easy-to-follow strength-training exercises
Farooqji
in
Cure Parkinson's
3 years ago
CDNF, Potential DMT for Parkinson’s, May Work as Nasal Spray
A potential Parkinson’s therapy based on a protein with an ability to protect neurons — called recombinant (lab-made) human cerebral dopamine neurotrophic factor (rhCDNF) — has been transformed into tiny nanoparticles that may allow for its use as a nasal spray, Herantis Pharma, its developer, announced
A potential Parkinson’s therapy based on a protein with an ability to protect neurons — called recombinant (lab-made) human cerebral dopamine neurotrophic factor (rhCDNF) — has been transformed into tiny nanoparticles that may allow for its use as a nasal spray, Herantis Pharma, its developer, announced
Hidden
in
Cure Parkinson's
3 years ago
Webinar on “Photobiomodulation as a Promising Treatment for Parkinson’s”
CEO, and founder of Vielight Inc. Dr. Lim will be talking to us about “Photobiomodulation as a Promising Treatment for Parkinson’s”. The session will be taking place at 7:30 p.m. London time on Monday the 20th of September. Can register and find all details in the Eventbrite invitation below;-
CEO, and founder of Vielight Inc. Dr. Lim will be talking to us about “Photobiomodulation as a Promising Treatment for Parkinson’s”. The session will be taking place at 7:30 p.m. London time on Monday the 20th of September. Can register and find all details in the Eventbrite invitation below;-
Farooqji
in
Cure Parkinson's
3 years ago
Caloric and galvanic vestibular stimulation for the treatment of Parkinson’s disease: rationale and prospects
I've posted about this before https://healthunlocked.com/cure-parkinsons/posts/146496859/caloric-vestibular-stimulation-for-the-management-of-motor-and-non-motor-symptoms-in-parkinsons-disease My idea is to periodically review and update topics. We have new people joining all the time (so sorry for people
I've posted about this before https://healthunlocked.com/cure-parkinsons/posts/146496859/caloric-vestibular-stimulation-for-the-management-of-motor-and-non-motor-symptoms-in-parkinsons-disease My idea is to periodically review and update topics. We have new people joining all the time (so sorry for people
Bolt_Upright
in
Cure Parkinson's
3 years ago
Resetting the Circadian Clock
Yes, I am kind of spitballing here. Could resetting the circadian rhythm help with PD? I posted this a couple days ago: Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic 2021 https://onlinelibrary.wiley.com/doi/full/10.1111/jpi.12759 The whole protocol is based on using
Yes, I am kind of spitballing here. Could resetting the circadian rhythm help with PD? I posted this a couple days ago: Treatment of isolated REM sleep behavior disorder using melatonin as a chronobiotic 2021 https://onlinelibrary.wiley.com/doi/full/10.1111/jpi.12759 The whole protocol is based on using
Bolt_Upright
in
Cure Parkinson's
3 years ago
Forced Exercise via a "non-contributing motorized" bike will NOT help reduce motor symptoms. Applies also to a typical motorized Treadmill
Jay Alberts is the guru when it comes to FE and PD. at about 16:00 in his video he addresses a critical issue re: using a motorized bike. He explains that the PwP MUST contribute to the pedaling stroke effort (it is critical to understand this distinction) to obtain any benefit, but his hypothesis probably
Jay Alberts is the guru when it comes to FE and PD. at about 16:00 in his video he addresses a critical issue re: using a motorized bike. He explains that the PwP MUST contribute to the pedaling stroke effort (it is critical to understand this distinction) to obtain any benefit, but his hypothesis probably
sharoncrayn
in
Cure Parkinson's
3 years ago
Fungus Among Us: High Ochratoxin A Found in People with Parkinsonism
Yes, Somic67 posted this same video 11 months ago. https://healthunlocked.com/cure-parkinsons/posts/144253830/pd-caused-by-fungus But I just saw the video, we get a lot of new people here, and I have some thoughts on this. I'm also going to pilfer from the LAJ12345 comment on the thread and their link
Yes, Somic67 posted this same video 11 months ago. https://healthunlocked.com/cure-parkinsons/posts/144253830/pd-caused-by-fungus But I just saw the video, we get a lot of new people here, and I have some thoughts on this. I'm also going to pilfer from the LAJ12345 comment on the thread and their link
Bolt_Upright
in
Cure Parkinson's
3 years ago
Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease 2021
Update 8/30/21: I ordered a hydrogen water generator ($180): H2 USB Sport MAXX Hydrogen Water Generator with Glass Bottle and Inhaler Adapter (Silver) Brand: H2WaterForLife https://www.amazon.com/gp/product/B07FKVYYL6/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1 I also spent $25 on H2Blue Hydrogen
Update 8/30/21: I ordered a hydrogen water generator ($180): H2 USB Sport MAXX Hydrogen Water Generator with Glass Bottle and Inhaler Adapter (Silver) Brand: H2WaterForLife https://www.amazon.com/gp/product/B07FKVYYL6/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1 I also spent $25 on H2Blue Hydrogen
Bolt_Upright
in
Cure Parkinson's
3 years ago
Lost control on urine
I was diagnosed with Parkinson's in 2018..Age 57 and good exercise was keeping me well except tremors in whole body..I was taking much lesser dose of C/L - 0.75 mg a day with pamipraxol 3.5 mg a day against prescription of 3.75 mg of C/L a day and 1 mg of rasagiline. Now I have lost control on urine.
I was diagnosed with Parkinson's in 2018..Age 57 and good exercise was keeping me well except tremors in whole body..I was taking much lesser dose of C/L - 0.75 mg a day with pamipraxol 3.5 mg a day against prescription of 3.75 mg of C/L a day and 1 mg of rasagiline. Now I have lost control on urine.
MerckK
in
Cure Parkinson's
3 years ago
Sodium Butyrate: Neuroprotective effects of short-chain fatty acids in MPTP induced mice model of Parkinson's disease 2021
https://pubmed.ncbi.nlm.nih.gov/33905875/ Gut microbial metabolites, SCFAs, were related with the occurrence and development of Parkinson's disease (PD). But the effects of different short-chain fatty acids (SCFAs) on PD and involving mechanisms are still undefined. In this study we evaluate the effects
https://pubmed.ncbi.nlm.nih.gov/33905875/ Gut microbial metabolites, SCFAs, were related with the occurrence and development of Parkinson's disease (PD). But the effects of different short-chain fatty acids (SCFAs) on PD and involving mechanisms are still undefined. In this study we evaluate the effects
Bolt_Upright
in
Cure Parkinson's
3 years ago
Parkinson’s disease patients’ short chain fatty acids production capacity after in vitro fecal fiber fermentation 2021
Inulin beat out resistant starches for butyrate production but both helped. https://www.nature.com/articles/s41531-021-00215-5 To conclude, this study demonstrates that dietary fiber stimulates butyrate production in PD patients despite decreased butyrate-producing bacteria. However, the butyrate production
Inulin beat out resistant starches for butyrate production but both helped. https://www.nature.com/articles/s41531-021-00215-5 To conclude, this study demonstrates that dietary fiber stimulates butyrate production in PD patients despite decreased butyrate-producing bacteria. However, the butyrate production
Bolt_Upright
in
Cure Parkinson's
3 years ago
Role and Mechanism of Gut Microbiota in Human Disease 2021
Full article: https://www.frontiersin.org/articles/10.3389/fcimb.2021.625913/full Despite the findings of an increased Bifidobacterium in PD, a study showed that a decrease in Bifidobacterium later in disease may be able to predict whether PD stage is going to deteriorate or not. This implicates that
Full article: https://www.frontiersin.org/articles/10.3389/fcimb.2021.625913/full Despite the findings of an increased Bifidobacterium in PD, a study showed that a decrease in Bifidobacterium later in disease may be able to predict whether PD stage is going to deteriorate or not. This implicates that
Bolt_Upright
in
Cure Parkinson's
3 years ago
Excellent Exercise session for hands and fingers dexterity
Join physiotherapist, Shelly Yu, for an exercise series focused on hand and dexterity challenges associated with Parkinson's Disease. Exercises in this series will target upper extremity movement, hand dexterity, grip strength, hand-finger coordination and overall arm function. As this is a hand and
Join physiotherapist, Shelly Yu, for an exercise series focused on hand and dexterity challenges associated with Parkinson's Disease. Exercises in this series will target upper extremity movement, hand dexterity, grip strength, hand-finger coordination and overall arm function. As this is a hand and
Farooqji
in
Cure Parkinson's
3 years ago
The gut microbiota metabolite propionate ameliorates intestinal epithelial barrier dysfunction-mediated Parkinson's disease via the AKT ...
The gut microbiota metabolite propionate ameliorates intestinal epithelial barrier dysfunction-mediated Parkinson's disease via the AKT signaling pathway Feb 2021 https://read.qxmd.com/read/33470765/the-gut-microbiota-metabolite-propionate-ameliorates-intestinal-epithelial-barrier-dysfunction-mediated-parkinson-s-disease-via-the-akt-signaling-pathway
The gut microbiota metabolite propionate ameliorates intestinal epithelial barrier dysfunction-mediated Parkinson's disease via the AKT signaling pathway Feb 2021 https://read.qxmd.com/read/33470765/the-gut-microbiota-metabolite-propionate-ameliorates-intestinal-epithelial-barrier-dysfunction-mediated-parkinson-s-disease-via-the-akt-signaling-pathway
Bolt_Upright
in
Cure Parkinson's
3 years ago
Creatine supplements - any evidence on possible benefits?
We have seen a few research papers suggesting that creatine supplementation might help ward off neurodegenerative diseases, and also improve cognitive function. From a post of 7 years ago, it looks as though there was a clinical trial involving PSP patients with this and some other supplements, but the
We have seen a few research papers suggesting that creatine supplementation might help ward off neurodegenerative diseases, and also improve cognitive function. From a post of 7 years ago, it looks as though there was a clinical trial involving PSP patients with this and some other supplements, but the
Epsilon12
in
PSP Association
3 years ago
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