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Autoimmune Autonomic Ganglionopathy Associated with Voltage-Gated Potassium Channel Antibodies
When dysautonomia co-occurs with motor neuron disease it is called ALS plus syndrome aka
parkinsonism
. I came across a recent article about Clive Svendsen, PhD at Cedars-Sinai who said, "We don't think ALS is one disease." Is Parkinson's one disease? SE
When dysautonomia co-occurs with motor neuron disease it is called ALS plus syndrome aka
parkinsonism
. I came across a recent article about Clive Svendsen, PhD at Cedars-Sinai who said, "We don't think ALS is one disease." Is Parkinson's one disease? SE
SilentEchoes
in
Cure Parkinson's
2 years ago
Mild regression: is it B1 or COVID
Hello everyone, Ten days ago, I got COVID, with mild symptoms. At the time, I had started B1 , still ramping up the dose, with quite some success. In particular I had observed with great surprise and satisfaction how the tremor in my left hand had improved . It was mild on day 1 with COVID symptoms.-
Hello everyone, Ten days ago, I got COVID, with mild symptoms. At the time, I had started B1 , still ramping up the dose, with quite some success. In particular I had observed with great surprise and satisfaction how the tremor in my left hand had improved . It was mild on day 1 with COVID symptoms.-
enjoy2013
in
Cure Parkinson's
2 years ago
Dexmedetomidine attenuates motor deficits via restoring the function of neurons in the nigrostriatal circuit in Parkinson's disease - mice
Dexmedetomidine attenuates motor deficits via restoring the function of neurons in the nigrostriatal circuit in Parkinson's disease model mice https://pubmed.ncbi.nlm.nih.gov/35150656/ Dexmedetomidine (DEX) is a sedative and analgesic drug.
Dexmedetomidine attenuates motor deficits via restoring the function of neurons in the nigrostriatal circuit in Parkinson's disease model mice https://pubmed.ncbi.nlm.nih.gov/35150656/ Dexmedetomidine (DEX) is a sedative and analgesic drug.
Hidden
in
Cure Parkinson's
2 years ago
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Palmitoylethanolamide - Luteolin: Kind of Interesting
So I was bouncing around and found this article: Palmitoylethanolamide/Luteolin as Adjuvant Therapy to Improve an Unusual Case of Camptocormia in a Patient with Parkinson’s Disease: A Case Report 2021 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8794485/ This is a single case report about a fairly
So I was bouncing around and found this article: Palmitoylethanolamide/Luteolin as Adjuvant Therapy to Improve an Unusual Case of Camptocormia in a Patient with Parkinson’s Disease: A Case Report 2021 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8794485/ This is a single case report about a fairly
Bolt_Upright
in
Cure Parkinson's
2 years ago
Came across this book while researching Wahls protocol on recovery from Alzheimer's and neuro degeneration.
https://terrywahls.com/new-book-release-from-dr-dale-bredesen-the-first-survivors-of-alzheimers/ It looks like many of the supplements recommended on HU plus a few more have been used to treat Alzheimers for some successfully. For instance to restore balance btw glutamate to GABA with valerian, B6 and
https://terrywahls.com/new-book-release-from-dr-dale-bredesen-the-first-survivors-of-alzheimers/ It looks like many of the supplements recommended on HU plus a few more have been used to treat Alzheimers for some successfully. For instance to restore balance btw glutamate to GABA with valerian, B6 and
Sydney75
in
Cure Parkinson's
2 years ago
Cannabis and its derivatives for the use of motor symptoms in Parkinson’s disease: a systematic review and meta-analysis
Cannabis and its derivatives for the use of motor symptoms in Parkinson’s disease: a systematic review and meta-analysis 2021 https://journals.sagepub.com/doi/full/10.1177/17562864211018561 "Results: Fifteen studies, including six RCTs, were analyzed. Of these, 12/15 (80%) mention concomitant treatment
Cannabis and its derivatives for the use of motor symptoms in Parkinson’s disease: a systematic review and meta-analysis 2021 https://journals.sagepub.com/doi/full/10.1177/17562864211018561 "Results: Fifteen studies, including six RCTs, were analyzed. Of these, 12/15 (80%) mention concomitant treatment
Bolt_Upright
in
Cure Parkinson's
2 years ago
The 'right' kind of Magnesium supplement?
For the past couple of years I've been taking Magnesium L Threonate, for night cramps and it's worked extremely well but a couple of weeks ago, I had to switch to Magnesium Oxide as I couldn't get my usual. In any case, since I switched, my tummy has not been right (diarrhoea). Could the Magnesium Oxide
For the past couple of years I've been taking Magnesium L Threonate, for night cramps and it's worked extremely well but a couple of weeks ago, I had to switch to Magnesium Oxide as I couldn't get my usual. In any case, since I switched, my tummy has not been right (diarrhoea). Could the Magnesium Oxide
Mlinde
in
Thyroid UK
2 years ago
The Neuroprotective Effects of Cannabis-Derived Phytocannabinoids and Resveratrol in Parkinson’s Disease: A Systematic Review of Pre-clinica
The Neuroprotective Effects of Cannabis-Derived Phytocannabinoids and Resveratrol in Parkinson’s Disease: A Systematic Review of Pre-clinical Studies https://www.preprints.org/manuscript/202111.0050/v1 This is not peer reviewed. " Abstract Currently, there are no pharmacological treatments able to reverse
The Neuroprotective Effects of Cannabis-Derived Phytocannabinoids and Resveratrol in Parkinson’s Disease: A Systematic Review of Pre-clinical Studies https://www.preprints.org/manuscript/202111.0050/v1 This is not peer reviewed. " Abstract Currently, there are no pharmacological treatments able to reverse
Bolt_Upright
in
Cure Parkinson's
2 years ago
Gemfibrozil Protects Dopaminergic Neurons in a MouseModel of Parkinson’s Disease via PPARa-DependentAstrocytic GDNF Pathway 2021
Gemfibrozil Protects Dopaminergic Neurons in a MouseModel of Parkinson’s Disease via PPARa-DependentAstrocytic GDNF Pathway 2021 https://www.jneurosci.org/content/jneuro/41/10/2287.full.pdf "Parkinson’s disease (PD) is the most common neurodegenerative movement disorder in humans. Despite intense investigations
Gemfibrozil Protects Dopaminergic Neurons in a MouseModel of Parkinson’s Disease via PPARa-DependentAstrocytic GDNF Pathway 2021 https://www.jneurosci.org/content/jneuro/41/10/2287.full.pdf "Parkinson’s disease (PD) is the most common neurodegenerative movement disorder in humans. Despite intense investigations
Bolt_Upright
in
Cure Parkinson's
2 years ago
From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson's disease? (Starting my NAC again!)2022
This new article covers combining Stem Cells Secretome (SCS) and NAC to treat PD. From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson's disease? https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8552835/ "Abstract Parkinson's disease is the second most
This new article covers combining Stem Cells Secretome (SCS) and NAC to treat PD. From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson's disease? https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8552835/ "Abstract Parkinson's disease is the second most
Bolt_Upright
in
Cure Parkinson's
2 years ago
Anavex Life Sciences Announces Presentation of Phase 2 Clinical Biomarker Data from ANAVEX®2-73-PDD-001 Parkinson’s Disease Dementia Study
https://finance.yahoo.com/news/anavex-life-sciences-announces-presentation-110000370.html All MDS-UPDRS Part I, II, III, IV sub-scores improved, including substantial majority of individual items between 71% and 92% SIGMAR1 mRNA expression significantly increased in ANAVEX®2-73-treated patients vs placebo
https://finance.yahoo.com/news/anavex-life-sciences-announces-presentation-110000370.html All MDS-UPDRS Part I, II, III, IV sub-scores improved, including substantial majority of individual items between 71% and 92% SIGMAR1 mRNA expression significantly increased in ANAVEX®2-73-treated patients vs placebo
John_morris71
in
Cure Parkinson's
2 years ago
Binaural Beats: I have not figured this out (Feel welcome to offer suggestions)
So I am trying to figure out if Binaural Beats can help with brain plasticity. I have not figured it out yet. I did find a free program to create my own Binaural Beats: http://gnaural.sourceforge.net/ And I found what looks to be a well done YouTube video where I could copy some bonaural beats: https
So I am trying to figure out if Binaural Beats can help with brain plasticity. I have not figured it out yet. I did find a free program to create my own Binaural Beats: http://gnaural.sourceforge.net/ And I found what looks to be a well done YouTube video where I could copy some bonaural beats: https
Bolt_Upright
in
Cure Parkinson's
2 years ago
dopamine precursors, SuperDopa and SuperDopAmid as potential neuroprotective agents for slowing Parkinsons
Dopamine precursors, AcCys-L-Dopa-Cys-amide (SuperDopa) & N-acetylcysteine+DopAmide (SuperDopAmide), as potential neuroprotective agents for slowing Parkinsons https://www.nature.com/articles/s41419-022-04667-2 https://twitter.com/ScienceofPD/status/1503084705578688515 from Yissum http://www.yissum.co.il
Dopamine precursors, AcCys-L-Dopa-Cys-amide (SuperDopa) & N-acetylcysteine+DopAmide (SuperDopAmide), as potential neuroprotective agents for slowing Parkinsons https://www.nature.com/articles/s41419-022-04667-2 https://twitter.com/ScienceofPD/status/1503084705578688515 from Yissum http://www.yissum.co.il
Hidden
in
Cure Parkinson's
2 years ago
Adipose fat derive stem cell treatment for Parkinson's
Hi. I am in New Zealand and have found a doctor who does stem cell infusions to help with Parkinson's. The stem cell are adipose fat cells. They are harvested by way of small liposuction procedure. They take 50ml .Then the stem cells are separated and then put back in intravenously via a drip in arm
Hi. I am in New Zealand and have found a doctor who does stem cell infusions to help with Parkinson's. The stem cell are adipose fat cells. They are harvested by way of small liposuction procedure. They take 50ml .Then the stem cells are separated and then put back in intravenously via a drip in arm
20fatcats
in
Cure Parkinson's
2 years ago
Presentation by Dr. Jonathan Sackner-Bernstein: "What If I Discovered the Silver Bullet?" (rescheduled)
I am delighted to announce that this rescheduled zoom session will be taking place at 7.30 pm London time on Monday, the 28th of March. We will be using a Zoom Webinar format instead of a Zoom Meeting to avoid the problems that we had last time. This will be seamless for our participants. Dr. Jonathan
I am delighted to announce that this rescheduled zoom session will be taking place at 7.30 pm London time on Monday, the 28th of March. We will be using a Zoom Webinar format instead of a Zoom Meeting to avoid the problems that we had last time. This will be seamless for our participants. Dr. Jonathan
Michel0220
in
Cure Parkinson's
2 years ago
My theory; High dose melatonin increases glutamate Excitotoxicity which is a primary cause of neurodegeneration in PD
(Editing to add; I want to be wrong about this! I likely am wrong. But given the importance, it is worth confirming. ) This is my THEORY backed up by what I am researching. I will post more on this as soon as I compile more information. I think this is so urgent that I am putting this out now. The
(Editing to add; I want to be wrong about this! I likely am wrong. But given the importance, it is worth confirming. ) This is my THEORY backed up by what I am researching. I will post more on this as soon as I compile more information. I think this is so urgent that I am putting this out now. The
Hidden
in
Cure Parkinson's
2 years ago
HYPERHOMOCYSTEINEMIA AND ITS TREATMENT IN PATIENTS WITH PARKINSON’S DISEASE 2016 (Treat it with folic acid?)
HYPERHOMOCYSTEINEMIA AND ITS TREATMENT IN PATIENTS WITH PARKINSON’S DISEASE 2016 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5034996/ Long story short: About 20% of PwP have abnormally high homocysteine. And even when it is not abnormally high, it is still higher than non PwP. There does not seem
HYPERHOMOCYSTEINEMIA AND ITS TREATMENT IN PATIENTS WITH PARKINSON’S DISEASE 2016 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5034996/ Long story short: About 20% of PwP have abnormally high homocysteine. And even when it is not abnormally high, it is still higher than non PwP. There does not seem
Bolt_Upright
in
Cure Parkinson's
2 years ago
Chronic Glutamate Toxicity in Neurodegenerative Diseases
It is established that glutamate exitotoxicity contributes to neurodegeneration in PD and other ND diseases. I am endeavoring to determine what we can do to minimize or stop this. quotes: Evidence for Glutamate Dysregulation and Excitotoxicity in Different Neurodegenerative Diseases Excitotoxicity
It is established that glutamate exitotoxicity contributes to neurodegeneration in PD and other ND diseases. I am endeavoring to determine what we can do to minimize or stop this. quotes: Evidence for Glutamate Dysregulation and Excitotoxicity in Different Neurodegenerative Diseases Excitotoxicity
Hidden
in
Cure Parkinson's
2 years ago
New clinical trial registered: The effect of gluten-free diet on Parkinsonism (GFREEPARK)
https://clinicaltrials.gov/ct2/show/NCT05238545
https://clinicaltrials.gov/ct2/show/NCT05238545
Hidden
in
Cure Parkinson's
2 years ago
Encouraging results from the phase-I trial! The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in PD
Highlights
• Oral NR increases brain NAD levels in individuals with Parkinson’s disease • NR intake alters cerebral metabolism in Parkinson’s disease • Cerebral NAD increase is associated with clinical improvement in Parkinson’s disease • NR induces transcription of mitochondrial, lysosomal, and
Highlights
• Oral NR increases brain NAD levels in individuals with Parkinson’s disease • NR intake alters cerebral metabolism in Parkinson’s disease • Cerebral NAD increase is associated with clinical improvement in Parkinson’s disease • NR induces transcription of mitochondrial, lysosomal, and
Hidden
in
Cure Parkinson's
2 years ago
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