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Iodine avidity in papillary and poorly differentiated thyroid cancer is predicted by immunohistochemical and molecular work-up
The multivariable modelling showed that tumour tissue localisation (primary tumour or lymph node
metastasis
), histological subtype, TPO and NIS expression and TERT promoter mutation were each independent predictors of iodine avidity that could explain 68% of the observed variation of iodine avidity.
The multivariable modelling showed that tumour tissue localisation (primary tumour or lymph node
metastasis
), histological subtype, TPO and NIS expression and TERT promoter mutation were each independent predictors of iodine avidity that could explain 68% of the observed variation of iodine avidity.
helvella
Thyroid UK
in
Thyroid UK
1 year ago
UK based warriors, what was your second line of treatment offered after Ibrance and Letrozole?
Hi, my Ibrance+ Letrozole stopped working after 2 years 3 months. If you have the same diagnoses and the same drugs for your 1st line of treatment and live in the UK, please let me know what was your second line. Thank you. My dx is MBC ER/PR+ HER2- age 47 postmenopausal ( oophorectomy) lesions
Hi, my Ibrance+ Letrozole stopped working after 2 years 3 months. If you have the same diagnoses and the same drugs for your 1st line of treatment and live in the UK, please let me know what was your second line. Thank you. My dx is MBC ER/PR+ HER2- age 47 postmenopausal ( oophorectomy) lesions
R7777
in
SHARE Metastatic Breast Cancer
1 year ago
A new bone lesion
hello, I was diagnosed in June 2022. Started Ibrance and Letrozole in July. First scan after treatment was started was in November and it showed no progression. My scan last week showed a slight progression in one area of bone Mets and one new lesion. Any ideas what may be next?
hello, I was diagnosed in June 2022. Started Ibrance and Letrozole in July. First scan after treatment was started was in November and it showed no progression. My scan last week showed a slight progression in one area of bone Mets and one new lesion. Any ideas what may be next?
lovnmycat
in
SHARE Metastatic Breast Cancer
1 year ago
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I also take it as grated the the wheels are going to, if not fall off develop a few loose nuts as we all get older' I also haven't mentioned
metastasis
that's because as yet I haven't had that particular scan (The NM bone for the whole body is due Aug 2nd) Well you guys , my peers, I'm sure are well
I also take it as grated the the wheels are going to, if not fall off develop a few loose nuts as we all get older' I also haven't mentioned
metastasis
that's because as yet I haven't had that particular scan (The NM bone for the whole body is due Aug 2nd) Well you guys , my peers, I'm sure are well
Gollam
in
Advanced Prostate Cancer
1 year ago
Jaw mets
The specialist thinks it's a
metastasis
in his jaw bone and has referred him back to the oncologist for a pet scan to confirm. He has had one go of lu177 in December and is scheduled for the next one on Jan 26th.
The specialist thinks it's a
metastasis
in his jaw bone and has referred him back to the oncologist for a pet scan to confirm. He has had one go of lu177 in December and is scheduled for the next one on Jan 26th.
Omc64
in
Advanced Prostate Cancer
1 year ago
Xofigo experience and thoughts requested
He has 7 detectable bone
metastasis
, but had not experienced pain as yet. Gleason 9, PSA is 17 and trending upward, after 8 years on Lupron post PR and one year on Xtandi.
He has 7 detectable bone
metastasis
, but had not experienced pain as yet. Gleason 9, PSA is 17 and trending upward, after 8 years on Lupron post PR and one year on Xtandi.
Tinuriel
in
Advanced Prostate Cancer
1 year ago
Wondering about meds for high cholesterol
Hi fellow warriors, I have been on Letrozole and Ibrance for the last 2 years. I was diagnosed stage 4 de novo in late 2014. Mets were in liver only. I did Taxol, Herceptin and Perjeta for about 4 months, then Herceptin , Perjeta and Faslodex until 2019. I then was able to do just the Faslodex until
Hi fellow warriors, I have been on Letrozole and Ibrance for the last 2 years. I was diagnosed stage 4 de novo in late 2014. Mets were in liver only. I did Taxol, Herceptin and Perjeta for about 4 months, then Herceptin , Perjeta and Faslodex until 2019. I then was able to do just the Faslodex until
SaraJukebox
in
SHARE Metastatic Breast Cancer
1 year ago
The emerging role of fatty acid binding protein 5 (FABP5) in cancers
"[u][i]They also significantly suppressed the expression of the fatty acid-binding protein 5 gene, which plays critical roles in cell growth and
metastasis
in prostate cancer.[/i][/u]" I was wondering about commonly available grape seed extracts.
"[u][i]They also significantly suppressed the expression of the fatty acid-binding protein 5 gene, which plays critical roles in cell growth and
metastasis
in prostate cancer.[/i][/u]" I was wondering about commonly available grape seed extracts.
pca2004
in
Fight Prostate Cancer
1 year ago
My friend had his PETscan.
My read is this is good; no
metastasis
that they are aware of. Feedback very much appreciated. Hump Study Result Impression IMPRESSION: 1. Focus of radiotracer uptake seen in the left peripheral zone, consistent with MRI findings, with max SUV of 7.8.
My read is this is good; no
metastasis
that they are aware of. Feedback very much appreciated. Hump Study Result Impression IMPRESSION: 1. Focus of radiotracer uptake seen in the left peripheral zone, consistent with MRI findings, with max SUV of 7.8.
WhatHump
in
Prostate Cancer Network
1 year ago
Ovarian Cancer spread to spine? Does anyone have any experience with this (PetCT scan pic included)
Her PetCT results needed to be checked by doctor council before they could give her Avastin and they wrote they suspect
metastasis
on spine and just came home DEVASTATED and crying.. Her onco sent her to some kind of bone or spine scan I forgot how its called so that is our next step next week.
Her PetCT results needed to be checked by doctor council before they could give her Avastin and they wrote they suspect
metastasis
on spine and just came home DEVASTATED and crying.. Her onco sent her to some kind of bone or spine scan I forgot how its called so that is our next step next week.
Yoman282
in
My Ovacome
1 year ago
Missing dose
I have returned from travel with a cold- tested negative for COVID. I have Herceptin / perjeta in 2 days, I know I will not be better and I am worried they will tell me not to come in ( I am calling nurse tomorrow). Is it ok to miss dose? If they delay do they delay for a week or miss that dose
I have returned from travel with a cold- tested negative for COVID. I have Herceptin / perjeta in 2 days, I know I will not be better and I am worried they will tell me not to come in ( I am calling nurse tomorrow). Is it ok to miss dose? If they delay do they delay for a week or miss that dose
Onedayatatime60
in
SHARE Metastatic Breast Cancer
1 year ago
April 2023 Update
The scan showed no enlarged lymph nodes, and no obvious
metastasis
. It did however pick up a very significant & solid growth on my thyroid. I can’t get a needle biopsy until late August 2023. I’m not worried about that at this point.
The scan showed no enlarged lymph nodes, and no obvious
metastasis
. It did however pick up a very significant & solid growth on my thyroid. I can’t get a needle biopsy until late August 2023. I’m not worried about that at this point.
TottenhamMan
in
Advanced Prostate Cancer
1 year ago
Anastrozole for one month but seeing progression
how long do I wait to see if Anastrozole is going to help? I started exactly one month ago and the first couple weeks there was a lot less swelling but the last week I have a lot more pain around my shoulder near the tumor and my scapula area. The whole area is really tight and I now hav3 even less
how long do I wait to see if Anastrozole is going to help? I started exactly one month ago and the first couple weeks there was a lot less swelling but the last week I have a lot more pain around my shoulder near the tumor and my scapula area. The whole area is really tight and I now hav3 even less
HbbM
in
SHARE Metastatic Breast Cancer
1 year ago
The battle is over
Do chemo early when you are stronger- I suspect the results and outcome may be better than starting some of the drugs used especially if there is bone
metastasis
. 2. Radiation helps with pain.
Do chemo early when you are stronger- I suspect the results and outcome may be better than starting some of the drugs used especially if there is bone
metastasis
. 2. Radiation helps with pain.
Hidden
in
Advanced Prostate Cancer
1 year ago
xeloda and appetite
I'm on round 4 of Xeloda and my appetite is very poor. I'm losing weight which isn't good. Most foods just sound "gross" to me. Rice, pasta, cereals and yogurts are good but not enough protein/carbs. Anyone have some ideas on foods that have what I need and may be appealing to me? thanks.
I'm on round 4 of Xeloda and my appetite is very poor. I'm losing weight which isn't good. Most foods just sound "gross" to me. Rice, pasta, cereals and yogurts are good but not enough protein/carbs. Anyone have some ideas on foods that have what I need and may be appealing to me? thanks.
Marla61
in
SHARE Metastatic Breast Cancer
1 year ago
Prolaris Test Helps ID Higher-risk Patients Who May Safely Skip ADT when receiving radiation for PCa
This Myriad Genetics’ test was found to be superior to other methods at predicting cancer spread (
metastasis
) in these patients, and thereby at distinguishing those who could avoid ADT The findings, “Association of the clinical cell-cycle risk score with
metastasis
after radiation therapy and identification
This Myriad Genetics’ test was found to be superior to other methods at predicting cancer spread (
metastasis
) in these patients, and thereby at distinguishing those who could avoid ADT The findings, “Association of the clinical cell-cycle risk score with
metastasis
after radiation therapy and identification
George71
in
Fight Prostate Cancer
1 year ago
MBC Journey so far
I was diagnosed with Primary and MBC the same time in 2017 they started me on Letrozole which worked well for about 3 years since then tried a number if other hormonal therapies that did not work for long or not at all (Ibrance and Everolimous) they have now decided to move me onto Chemo Xeloda, had
I was diagnosed with Primary and MBC the same time in 2017 they started me on Letrozole which worked well for about 3 years since then tried a number if other hormonal therapies that did not work for long or not at all (Ibrance and Everolimous) they have now decided to move me onto Chemo Xeloda, had
Matthew2004
in
SHARE Metastatic Breast Cancer
1 year ago
metastatic Lobular
Recently diagnosed metastatic lobular to peritoneal only and waiting arrival of Kisquali. Started Letrozole a week and a half ago. Am taking Xgeva shots going on 9 years. Is it possible to bring down markers with Letrozole only if you have a slow grower? Has anyone had success with that? I had a
Recently diagnosed metastatic lobular to peritoneal only and waiting arrival of Kisquali. Started Letrozole a week and a half ago. Am taking Xgeva shots going on 9 years. Is it possible to bring down markers with Letrozole only if you have a slow grower? Has anyone had success with that? I had a
CLC-52
in
SHARE Metastatic Breast Cancer
1 year ago
Questions about hormone therapy...
Greetings, I was diagnosed with prostate cancer, Gleason 8, no indication of
metastasis
in January. I just had a radical prostatectomy, including the removal of nerves.
Greetings, I was diagnosed with prostate cancer, Gleason 8, no indication of
metastasis
in January. I just had a radical prostatectomy, including the removal of nerves.
JetBoy
in
Prostate Cancer And Gay Men
1 year ago
Relugolix/Orgovyx with pelvic radiation?
Should the scan show
metastasis
in the pelvic region, I will most likely have pelvic radiation with a short course of ADT. Has anyone had Relugolix in lieu of Lupron with pelvic radiation? I like the idea of faster testosterone recovery after finishing Relugolix in comparison to Lupron.
Should the scan show
metastasis
in the pelvic region, I will most likely have pelvic radiation with a short course of ADT. Has anyone had Relugolix in lieu of Lupron with pelvic radiation? I like the idea of faster testosterone recovery after finishing Relugolix in comparison to Lupron.
bitittle
in
Advanced Prostate Cancer
1 year ago
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