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Need an Advise and Info on Very Experienced Doctors and Centers to do Proton Treatment of the Prostate in Oligometastatic Setting
There was three confirmed pelvic lympnodes and one right femur
metastasis
. Lymphnodes were cleared by Lu-177 and Femur by SBRT.
There was three confirmed pelvic lympnodes and one right femur
metastasis
. Lymphnodes were cleared by Lu-177 and Femur by SBRT.
CurrentSEO
in
Advanced Prostate Cancer
1 year ago
What next option available if CDK4/6 get failed
Hi all and Dr. Sumeet Shah one of my relative diagnosed with oligometastatic left breast cancer in 2015 treated with chemo (4 Cycle 5FEC and 1 Cycle of Docetaxel) than surgery (lumpectomy) again 2 cycle of 5FEC chemo 2016 march NED put on tamoxifen 20 mg regular check up and in 2021 it relapsed in
Hi all and Dr. Sumeet Shah one of my relative diagnosed with oligometastatic left breast cancer in 2015 treated with chemo (4 Cycle 5FEC and 1 Cycle of Docetaxel) than surgery (lumpectomy) again 2 cycle of 5FEC chemo 2016 march NED put on tamoxifen 20 mg regular check up and in 2021 it relapsed in
Deepak1965
in
Breast Cancer India
1 year ago
Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic PC. The EXTEND Phase 2 Randomized Clinical Trial
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
tango65
in
Advanced Prostate Cancer
1 year ago
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Stage 4 Prostate Cancer treated with Xtandi- 3 pills & Zolodex; 1.5 yrs diagnosed, now left side pain under ribs
Some
Metastasis
to the ribs- right and left side. Thoughts are that pain could be muscular. Ultrasound is not definitive but the oncologist is reluctant to do a colonoscopy. Has anyone experienced any pain similar? I am periodically taking Advil to relieve the discomfort.
Some
Metastasis
to the ribs- right and left side. Thoughts are that pain could be muscular. Ultrasound is not definitive but the oncologist is reluctant to do a colonoscopy. Has anyone experienced any pain similar? I am periodically taking Advil to relieve the discomfort.
Hidden
in
Advanced Prostate Cancer
1 year ago
Taxol For MBC
Good morning. After taking Ibrance w/ Fulvestrant for 8 mos., it stopped working 2 mos. ago. The next plan is Piqray w/ Fulvestrant, but the side effect were too much - especially to my one remaining eye (the mucous membrane). Next plan, which I should begin this Wed. if ins. approves, is Taxol infusions
Good morning. After taking Ibrance w/ Fulvestrant for 8 mos., it stopped working 2 mos. ago. The next plan is Piqray w/ Fulvestrant, but the side effect were too much - especially to my one remaining eye (the mucous membrane). Next plan, which I should begin this Wed. if ins. approves, is Taxol infusions
macspow
in
SHARE Metastatic Breast Cancer
1 year ago
is it too much to hope for shrinkage?
I’m stage 4 in breast, liver, multiple bones and lung. Been attempting completely natural for over 2 years. Last scan showed some improvement but the breast tumor is getting harder and larger. So now going all in with what my amazing oncologist is suggesting. Started on Ibrance and Anastrozole this last
I’m stage 4 in breast, liver, multiple bones and lung. Been attempting completely natural for over 2 years. Last scan showed some improvement but the breast tumor is getting harder and larger. So now going all in with what my amazing oncologist is suggesting. Started on Ibrance and Anastrozole this last
HbbM
in
SHARE Metastatic Breast Cancer
1 year ago
Faslodex + Ibrance - new mets
Hi everyone! My mother is on ibrance and faslodex for 15 cycles. she had pelvic metastases that are still under control, but there are new ones on her spine. she will continue to receive the same therapy. Does anyone have a similar experience? is it possible to keep the disease under control even
Hi everyone! My mother is on ibrance and faslodex for 15 cycles. she had pelvic metastases that are still under control, but there are new ones on her spine. she will continue to receive the same therapy. Does anyone have a similar experience? is it possible to keep the disease under control even
Goga156
in
SHARE Metastatic Breast Cancer
1 year ago
Monoamine oxidase A (MAOA): A promising target for prostate cancer therapy
Cancer-cell-derived MAOA also enables cancer-stromal cell interaction involving bone stromal cells and nerve cells by secretion of Hedgehog and class 3 semaphorin molecules respectively to modulate the tumor microenvironment in favor of invasion and
metastasis
.
Cancer-cell-derived MAOA also enables cancer-stromal cell interaction involving bone stromal cells and nerve cells by secretion of Hedgehog and class 3 semaphorin molecules respectively to modulate the tumor microenvironment in favor of invasion and
metastasis
.
pjoshea13
in
Fight Prostate Cancer
1 year ago
Holiday inspiration!
Hi lovely ladies, After reading about Beth’s amazing travels in New Zealand, I hope to encourage you to follow your dreams with travel when you can. I am from the UK, and was crushed when I had to cancel my planned silver wedding anniversary trip to New England twice, the first time because of the pandemic
Hi lovely ladies, After reading about Beth’s amazing travels in New Zealand, I hope to encourage you to follow your dreams with travel when you can. I am from the UK, and was crushed when I had to cancel my planned silver wedding anniversary trip to New England twice, the first time because of the pandemic
LibraryGeek
in
SHARE Metastatic Breast Cancer
1 year ago
Starting Xeloda soon
I am a rare case for Johns Hopkins. Dx de novo ER/Pr +, Her2 - almost 8 years ago. Two very tiny liver mets only. Did extremely well and achieved NED status on Ibrance and AI for 6.5 years when we noticed the primary site of cancer in the breast was growing. Switched to Faslodex and Fulvestrant.
I am a rare case for Johns Hopkins. Dx de novo ER/Pr +, Her2 - almost 8 years ago. Two very tiny liver mets only. Did extremely well and achieved NED status on Ibrance and AI for 6.5 years when we noticed the primary site of cancer in the breast was growing. Switched to Faslodex and Fulvestrant.
MeeyaNicole
in
SHARE Metastatic Breast Cancer
1 year ago
Colchicine and Inflammation Revisited
Inflammation is one of the two principle drivers of “The Hallmarks of Cancer” which are the common drivers of progression of cancer from initiation to invasion and spread, to developing resistance to treatments and ultimately to end stage
metastasis
.
Inflammation is one of the two principle drivers of “The Hallmarks of Cancer” which are the common drivers of progression of cancer from initiation to invasion and spread, to developing resistance to treatments and ultimately to end stage
metastasis
.
MateoBeach
in
Advanced Prostate Cancer
10 months ago
Colchicine and Inflammation Reconsidered
Inflammation is one of the two principle drivers of “The Hallmarks of Cancer” which are the common drivers of progression of cancer from initiation to invasion and spread, to developing resistance to treatments and ultimately to end stage
metastasis
.
Inflammation is one of the two principle drivers of “The Hallmarks of Cancer” which are the common drivers of progression of cancer from initiation to invasion and spread, to developing resistance to treatments and ultimately to end stage
metastasis
.
MateoBeach
in
Fight Prostate Cancer
10 months ago
Rant! Rant! Rant!
It’s hard to talk about cancer because there are so many things people do differently in treatment, so many choices we make. I don’t get offended much but someone said something today that kind of hit me the wrong way. I never understood why stage iv cancer patients were offended by those who didn’t
It’s hard to talk about cancer because there are so many things people do differently in treatment, so many choices we make. I don’t get offended much but someone said something today that kind of hit me the wrong way. I never understood why stage iv cancer patients were offended by those who didn’t
CatLady2022
in
SHARE Metastatic Breast Cancer
1 year ago
New liver Mets😢
Diagnosed 2014 ER positive breast cancer, mastectomy RHS chemo and 5 years on aromasin. 2020 diagnosed Mets in sternum, ribs and spine 10 rounds of radiation and faslodex, ibrance and xgeva with fantastic results. So new liver Mets have appeared after my tumours in my bones are stable. Shocked and
Diagnosed 2014 ER positive breast cancer, mastectomy RHS chemo and 5 years on aromasin. 2020 diagnosed Mets in sternum, ribs and spine 10 rounds of radiation and faslodex, ibrance and xgeva with fantastic results. So new liver Mets have appeared after my tumours in my bones are stable. Shocked and
Julesdubai
in
SHARE Metastatic Breast Cancer
1 year ago
Pet PSMA result
No new
metastasis
or locally recurrent disease. 2. Focal areas of low mild PSMA activity involving the T3 vertebral body and right 5th and left 6th ribs which Re favored to be benign fiven the low level activity. MiPSMA Expression score:1 My PSA has decreased from 1.6 to 0.39.
No new
metastasis
or locally recurrent disease. 2. Focal areas of low mild PSMA activity involving the T3 vertebral body and right 5th and left 6th ribs which Re favored to be benign fiven the low level activity. MiPSMA Expression score:1 My PSA has decreased from 1.6 to 0.39.
venecia1983
in
Advanced Prostate Cancer
1 year ago
Doxycycline
The matrix metalloproteinases (MMPs) play a significant role in the growth, invasion and
metastasis
of many tumors, including those of the prostate.
The matrix metalloproteinases (MMPs) play a significant role in the growth, invasion and
metastasis
of many tumors, including those of the prostate.
pca2004
in
Fight Prostate Cancer
1 year ago
Bone pain
Hello everyoneI'm 53 and have triple negative metastatic bone cancer. Found out when my femur fractured last October. I'm on Xeloda. My bones in hip and knee are starting to hurt more, even though my last PET scan was clear. Why is this happening?
Hello everyoneI'm 53 and have triple negative metastatic bone cancer. Found out when my femur fractured last October. I'm on Xeloda. My bones in hip and knee are starting to hurt more, even though my last PET scan was clear. Why is this happening?
luxie69
in
SHARE Metastatic Breast Cancer
1 year ago
Xeloda causing hand redness and extreme tenderness ... playing phone tag with onc's nurse
I am frustrated and feeling more vulnerable and overwhelmed than I've felt during most of my 19 year journey with MBC. On day 5 of 7 days off Xeloda, second round of two weeks on, one week off. I phoned the cancer center either two or three times yesterday and twice so far today. On top of that, I
I am frustrated and feeling more vulnerable and overwhelmed than I've felt during most of my 19 year journey with MBC. On day 5 of 7 days off Xeloda, second round of two weeks on, one week off. I phoned the cancer center either two or three times yesterday and twice so far today. On top of that, I
PJBinMI
in
SHARE Metastatic Breast Cancer
1 year ago
Fulvestrant side effects
Just wondering whether anyone on fulvestrant alone has experienced any of the potential side effects listed for this drug? Not the injection itself but afterwards. I had my 4th set of shots 3 weeks ago. The only side effect I experienced after the first 3 injections was fatigue but this time, 2 days
Just wondering whether anyone on fulvestrant alone has experienced any of the potential side effects listed for this drug? Not the injection itself but afterwards. I had my 4th set of shots 3 weeks ago. The only side effect I experienced after the first 3 injections was fatigue but this time, 2 days
valentinecalico
in
SHARE Metastatic Breast Cancer
1 year ago
Newly diagnosed after severe pain, nocturia and urine retention- can bone mets cause fractures and other issues?
I'm newly diagnosed with bone
metastasis
. Hips, spine , ribs. Feeling terrified and scared. Did anyone have bone fractures and other issues from bone mets? The survival stats are causing me a lot of distress.
I'm newly diagnosed with bone
metastasis
. Hips, spine , ribs. Feeling terrified and scared. Did anyone have bone fractures and other issues from bone mets? The survival stats are causing me a lot of distress.
Orion9899
in
Advanced Prostate Cancer
2 years ago
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