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Expanded label sought for 177Lu-PSMA-617 in prostate cancer: about time
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
Maxone73
in
Advanced Prostate Cancer
3 months ago
Spirulina and Chlorella
Hi, i was diagnosed with Rheumatoid arthritis 5 years ago and I'm on methotrexate and hydroxycloroquine. I'm was hoping to start taking spirulina and chlorella as they have so many health benefits but I not sure of any drug interactions. I've tried Google but I'm getting conflicting advice, some say
Hi, i was diagnosed with Rheumatoid arthritis 5 years ago and I'm on methotrexate and hydroxycloroquine. I'm was hoping to start taking spirulina and chlorella as they have so many health benefits but I not sure of any drug interactions. I've tried Google but I'm getting conflicting advice, some say
Maple1981
in
NRAS
3 months ago
Next NoSilverBullet webinar on 22nd of April: Dr M Sexton on “How can medical cannabis help people with Parkinson’s?”
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 22nd of April. Dr Michelle Sexton will be talking to us about “How can medical cannabis help people with Parkinson’s?” Please use the Eventbrite link below to register for
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 22nd of April. Dr Michelle Sexton will be talking to us about “How can medical cannabis help people with Parkinson’s?” Please use the Eventbrite link below to register for
Michel0220
in
Cure Parkinson's
3 months ago
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Update May 15, 2024
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
MsHope
in
Advanced Prostate Cancer
3 months ago
Reference Library of Papers about Dutasteride for Treating Prostate Cancer
Here is a library of 20 papers about using Dutasteride to treat prostate cancer. In one study, Dutasteride monotherapy reduces PSA by 50%, reduces prostate volume by 25%, and reduces tumor volume by 30%, after 6 months of treatment, compared to placebo (Moore, 2017). https://pubmed.ncbi.nlm.nih.gov
Here is a library of 20 papers about using Dutasteride to treat prostate cancer. In one study, Dutasteride monotherapy reduces PSA by 50%, reduces prostate volume by 25%, and reduces tumor volume by 30%, after 6 months of treatment, compared to placebo (Moore, 2017). https://pubmed.ncbi.nlm.nih.gov
janebob99
in
Advanced Prostate Cancer
3 months ago
pigment dispersion syndrome
Hi lovely people 😀 I have EDS, not lupus, but many of my symptoms are similar I’ve recently been dxd with pigment dispersion syndrome by an ophthalmologist at our regional eye hospital. It happens when pigment from the iris sheds onto other parts of the eye, causing inflammation and vision problems
Hi lovely people 😀 I have EDS, not lupus, but many of my symptoms are similar I’ve recently been dxd with pigment dispersion syndrome by an ophthalmologist at our regional eye hospital. It happens when pigment from the iris sheds onto other parts of the eye, causing inflammation and vision problems
MEGS53
in
LUPUS UK
3 months ago
Wife of Newly Diagnosed Husband - PSMA questions
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
EvFC
in
Advanced Prostate Cancer
4 months ago
Diabetes drug similar to Ozempic helped slow progression of Parkinson’s disease in small trial
https://www.cnbc.com/2024/04/04/drug-similar-to-ozempic-slowed-parkinsons-disease-in-small-trial.html And they are no longer manufacturing this older drug as it would be a "cheap" drug. It will be repurposed and cost $$$. I know I am being cynical. [i]Sanofi pulled lixisenatide from the market
https://www.cnbc.com/2024/04/04/drug-similar-to-ozempic-slowed-parkinsons-disease-in-small-trial.html And they are no longer manufacturing this older drug as it would be a "cheap" drug. It will be repurposed and cost $$$. I know I am being cynical. [i]Sanofi pulled lixisenatide from the market
Sydney75
in
Cure Parkinson's
4 months ago
starting statins and blood thinners
I just found out that I had a silent stroke in the past according to a recent MRA. I am starting a med that keeps platelets from sticking together and a statin. I am scared to death of the side effects. Any advice?
I just found out that I had a silent stroke in the past according to a recent MRA. I am starting a med that keeps platelets from sticking together and a statin. I am scared to death of the side effects. Any advice?
Milynda
in
Anticoagulation Support
4 months ago
Bee venom for the treatment of Parkinson’s disease: How far is it possible? 2017
Bee venom for the treatment of Parkinson’s disease: How far is it possible? 2017 https://sci-hub.st/10.1016/j.biopha.2017.04.065 A woman on FB Parkinson's Alternative Healing posted that wasp venom has made most of her symptoms go away. I am still trying to find out if she stopped her meds.
Bee venom for the treatment of Parkinson’s disease: How far is it possible? 2017 https://sci-hub.st/10.1016/j.biopha.2017.04.065 A woman on FB Parkinson's Alternative Healing posted that wasp venom has made most of her symptoms go away. I am still trying to find out if she stopped her meds.
Bolt_Upright
in
Cure Parkinson's
4 months ago
GLP1-R agonist improves Parkinson disease symptoms
"Lixisenatide can cross the blood-brain barrier and is known to have neuroprotective properties in https://www.ccjm.org/page/mds-2023/glp1-r-agonist-parkinson#:~:text=Lixisenatide%20can%20cross%20the%20blood,%2C%20University%20Hospital%20Bordeaux%2C%20France.
"Lixisenatide can cross the blood-brain barrier and is known to have neuroprotective properties in https://www.ccjm.org/page/mds-2023/glp1-r-agonist-parkinson#:~:text=Lixisenatide%20can%20cross%20the%20blood,%2C%20University%20Hospital%20Bordeaux%2C%20France.
Gcf51
in
Cure Parkinson's
4 months ago
Meta analysis of Eastern Cooperative Oncology Group(ECOG) PS predicts OS regardless of category, previous chemotherapy, and mPC population
”Overall, 75 studies, comprising 32,298 patients, were included. Most studies (72/75) included patients with mCRPC. Higher ECOG PS was associated with a significant increase in mortality risk, with the highest estimate observed among patients with mCRPC with an ECOG PS of ≥2 versus <2 (hazard ratio [
”Overall, 75 studies, comprising 32,298 patients, were included. Most studies (72/75) included patients with mCRPC. Higher ECOG PS was associated with a significant increase in mortality risk, with the highest estimate observed among patients with mCRPC with an ECOG PS of ≥2 versus <2 (hazard ratio [
Graham49
in
Advanced Prostate Cancer
4 months ago
PSA following Lupron and question on scans
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
alysona828
in
Advanced Prostate Cancer
4 months ago
question about macuna
hi Few questions. 1. Does macuna capsule must take with benserazide or carbidopa? 2. If so, i am taking 100mg levodopa/25mg benserazide(Madopar) if I want to add 400mg mucuna15% levodopa ; so I need to take extra benserazide? thx
hi Few questions. 1. Does macuna capsule must take with benserazide or carbidopa? 2. If so, i am taking 100mg levodopa/25mg benserazide(Madopar) if I want to add 400mg mucuna15% levodopa ; so I need to take extra benserazide? thx
limcheeese22
in
Cure Parkinson's
4 months ago
Stage 4 fibrosis of the Liver
I contracted Hepatitis A in 2020, undiagnosed for 2 months. Six months later I was told I had NALD and last year I was sent for ultrasound scans and blood tests to check for cancer. In March this year, I was told I had Stage 4 Fibrosis of the liver. Does anyone know if this can be reversed, any treatments
I contracted Hepatitis A in 2020, undiagnosed for 2 months. Six months later I was told I had NALD and last year I was sent for ultrasound scans and blood tests to check for cancer. In March this year, I was told I had Stage 4 Fibrosis of the liver. Does anyone know if this can be reversed, any treatments
Wi-llow
in
British Liver Trust
4 months ago
Timing of co-careldopa
I've written to US NLM regarding the difference of advice given when taken the co-careldopa pill, as follows....Thank you for contacting the U.S. National Library of Medicine (NLM). The details of your message are listed below. You can expect to hear from us within 2 to 5 business days. For additional
I've written to US NLM regarding the difference of advice given when taken the co-careldopa pill, as follows....Thank you for contacting the U.S. National Library of Medicine (NLM). The details of your message are listed below. You can expect to hear from us within 2 to 5 business days. For additional
Allypally49
in
Cure Parkinson's
4 months ago
FDA approves a new IND application of 225Ac-J591 (Actinium)
The FDA has granted clearance to an investigational new drug (IND) application for 225Ac-J591 (CONV01-α), a prostate-specific membrane antigen-targeted monoclonal antibody under investigation for the treatment of patients with advanced prostate cancer, announced Convergent Therapeutics, the developer
The FDA has granted clearance to an investigational new drug (IND) application for 225Ac-J591 (CONV01-α), a prostate-specific membrane antigen-targeted monoclonal antibody under investigation for the treatment of patients with advanced prostate cancer, announced Convergent Therapeutics, the developer
Maxone73
in
Advanced Prostate Cancer
4 months ago
Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
4 months ago
Cortisol test result
Hi, I have just had some blood test results come back today. Currently on 5.5mg, but have been taking 6mg (Sat 30th..Sun, Mon, Tues) as have had lots going on, bit stressful but good stress not bad! the 0.5mg did help. All results are ok including PV, ESR, CRP. Also had a basal cortisol test (partially
Hi, I have just had some blood test results come back today. Currently on 5.5mg, but have been taking 6mg (Sat 30th..Sun, Mon, Tues) as have had lots going on, bit stressful but good stress not bad! the 0.5mg did help. All results are ok including PV, ESR, CRP. Also had a basal cortisol test (partially
Saffron23
in
PMRGCAuk
4 months ago
'Wednesday Word"
Since my question yesterday was concerning 'brain fog', I thought my word for today should be [u][i]
encephalopathy
[/i][/u] - here are specifics about the word This is a blanket term referring to any brain dysfunction. It can commonly be called 'brain fog'. However, [u][i]
encephalopathy
Since my question yesterday was concerning 'brain fog', I thought my word for today should be [u][i]
encephalopathy
[/i][/u] - here are specifics about the word This is a blanket term referring to any brain dysfunction. It can commonly be called 'brain fog'. However, [u][i]
encephalopathy
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
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