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some PBC general pieces of information
Facts at-a-Glance Primary Biliary Cholangitis (PBC) affects mostly women, but more men are now being diagnosed. Primary Biliary Cholangitis (PBC) is a chronic disease in which the small bile ducts in the liver become injured and inflamed and are eventually destroyed. Researchers estimate that in the
Facts at-a-Glance Primary Biliary Cholangitis (PBC) affects mostly women, but more men are now being diagnosed. Primary Biliary Cholangitis (PBC) is a chronic disease in which the small bile ducts in the liver become injured and inflamed and are eventually destroyed. Researchers estimate that in the
DonnaBoll
Administrator
in
PBC Foundation
10 days ago
FEAR!
What do you do when your spouse drinks and is CRUELER than usual and you know you should get away but you fear for the cats, you had hip surgery last summer and still not that strong yet and now agoraphobia returns. Afraid to stay. Afraid to leave. Going to try to go to an Al Anon meeting if I get
What do you do when your spouse drinks and is CRUELER than usual and you know you should get away but you fear for the cats, you had hip surgery last summer and still not that strong yet and now agoraphobia returns. Afraid to stay. Afraid to leave. Going to try to go to an Al Anon meeting if I get
CatsandCheese
in
Anxiety and Depression Support
11 days ago
panic disorder
hello all I’m new to this and thought I would give this forum a go and see how living with anxiety affects other people as well as myself as I know a lot of people have these disorders. I would appreciate any advice, feedback and suggestions to help me live a normal life. I wish you all well as I know
hello all I’m new to this and thought I would give this forum a go and see how living with anxiety affects other people as well as myself as I know a lot of people have these disorders. I would appreciate any advice, feedback and suggestions to help me live a normal life. I wish you all well as I know
Anniemorris1
in
Anxiety and Depression Support
13 days ago
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diverticulitis
hello Well.., diverticulitis is not nice at all. New to me and having got to age 64 fairly unscathed apart from anxiety, am feeling a bit vulnerable. Woke with abdo pain +++ and was away visiting family struggled on but when I got home pain was worse and went to see Dr. Given abx and pain subsided
hello Well.., diverticulitis is not nice at all. New to me and having got to age 64 fairly unscathed apart from anxiety, am feeling a bit vulnerable. Woke with abdo pain +++ and was away visiting family struggled on but when I got home pain was worse and went to see Dr. Given abx and pain subsided
YogaFriend
in
Bowel Disease Support
5 months ago
Researchers from WEHI and Trento University (Italy) have answered an age-old question: which function helps mutant p53 fuel tumour growth?
The study revealed that the
loss of function
in the mutated p53 protein is the critical factor in cancer growth, disproving the previously suggested gain-of-function role. Using CRISPR gene editing, the researchers removed various mutated forms of p53 and found no change in cancer cell behavior
The study revealed that the
loss of function
in the mutated p53 protein is the critical factor in cancer growth, disproving the previously suggested gain-of-function role. Using CRISPR gene editing, the researchers removed various mutated forms of p53 and found no change in cancer cell behavior
Maxone73
in
Advanced Prostate Cancer
8 months ago
Progressing nanotechnology to improve targeted cancer treatment: not related to prostate cancer only
The article emphasizes the challenges in transitioning from lab findings to clinical applications, stressing the need for further research to optimize nanocarriers for cancer therapy. It explores the potential of nanocarriers and compounds for selective tumor targeting, including liposomes, nanoparticles
The article emphasizes the challenges in transitioning from lab findings to clinical applications, stressing the need for further research to optimize nanocarriers for cancer therapy. It explores the potential of nanocarriers and compounds for selective tumor targeting, including liposomes, nanoparticles
Maxone73
in
Advanced Prostate Cancer
8 months ago
update: Zanabrutinib vs Obenven (O&V)
We are praying for Gods wisdom (James1:5), and we’re leaning toward the Zanabrutinib. The infusions and time and distance will be impactful to my husbands work and he’s prefer to go the simpler route. We learned he’s still 13Q and TP53 negative and his lymph nodes are reduced (we have used ALT for
We are praying for Gods wisdom (James1:5), and we’re leaning toward the Zanabrutinib. The infusions and time and distance will be impactful to my husbands work and he’s prefer to go the simpler route. We learned he’s still 13Q and TP53 negative and his lymph nodes are reduced (we have used ALT for
Cb1391
in
CLL Support
8 months ago
serotonin syndrome
I have a mild case of serotin syndrome… done stuff I shouldn’t have but anxiety and depression is creeping back up on me…. The issue is I’m not sure if I’m really disappointed in people or if the syndrome talking … there times where it just easier to get lost in my made up reality then live in funk
I have a mild case of serotin syndrome… done stuff I shouldn’t have but anxiety and depression is creeping back up on me…. The issue is I’m not sure if I’m really disappointed in people or if the syndrome talking … there times where it just easier to get lost in my made up reality then live in funk
CorgiPower
in
Anxiety and Depression Support
18 days ago
After 25 days back on prednisone...
Thank you to all who advised on my previous post. I have almost completed the first month back on 20mg day of prednisone. The effect was immediate, pain gone, stiffness gone, fatigue better, am motivated and catching up with chores I had neglected for months. I feel more positive now, even started
Thank you to all who advised on my previous post. I have almost completed the first month back on 20mg day of prednisone. The effect was immediate, pain gone, stiffness gone, fatigue better, am motivated and catching up with chores I had neglected for months. I feel more positive now, even started
Biba5
in
PMRGCAuk
4 months ago
"ive lost myself" updated
"hi guys. just came back to give an update. so i got diagnosed with ocd, panic disorder, gad, whatever. i started buspirone because im generally sensitive to ssris and i thought it was working for a bit, but then it started giving me problems. i went off of it and then it gave me more problems. now i
"hi guys. just came back to give an update. so i got diagnosed with ocd, panic disorder, gad, whatever. i started buspirone because im generally sensitive to ssris and i thought it was working for a bit, but then it started giving me problems. i went off of it and then it gave me more problems. now i
thegoat123
in
Anxiety and Depression Support
21 days ago
potential DILI - advice?
hi everyone, I’m 29F, at the end of April I was hospitalised for e-coli, given anti biotics and PPI’s through my IV line for 3 days, then continued on oral anti biotics with PPI’s for 5 days My symptoms continued and my ALT/AST are at 952/370 and continuing to rise still today, I feel awful, nauseous
hi everyone, I’m 29F, at the end of April I was hospitalised for e-coli, given anti biotics and PPI’s through my IV line for 3 days, then continued on oral anti biotics with PPI’s for 5 days My symptoms continued and my ALT/AST are at 952/370 and continuing to rise still today, I feel awful, nauseous
eljd
in
British Liver Trust
22 days ago
B12 Crashing symptoms
can anybody else tell me their symptoms during B12 deficiency crash. I’m trying to figure out how bad I should be in order to request another shot.
can anybody else tell me their symptoms during B12 deficiency crash. I’m trying to figure out how bad I should be in order to request another shot.
Skieblue
in
Pernicious Anaemia Society
5 months ago
Active B12 blood result.
A friend’s ‘Active’ Vitamin B12 blood test result has fallen within the lower quarter of the Active B12 blood range. Anyone have any good advice please.
A friend’s ‘Active’ Vitamin B12 blood test result has fallen within the lower quarter of the Active B12 blood range. Anyone have any good advice please.
Coastwalker
in
Thyroid UK
5 months ago
Tuesday's 'Tip'
I've decided to incorporate some of Dr. Jones's wisdom into our Tuesday's 'Tips' These are all from his book [u][i]The Definitive Guide for Patients Who Have Primary Biliary Cholangitis.[/i][/u] This an amazing source of information on PBC from a world leading expert. I strongly encourage everyone
I've decided to incorporate some of Dr. Jones's wisdom into our Tuesday's 'Tips' These are all from his book [u][i]The Definitive Guide for Patients Who Have Primary Biliary Cholangitis.[/i][/u] This an amazing source of information on PBC from a world leading expert. I strongly encourage everyone
DonnaBoll
Administrator
in
PBC Foundation
23 days ago
continuing back pain
I was diagnose with 2b Ovarian Cancer in April 22. I had surgery and 6 rounds of Chemo. I have a very supportive team . I have had an MRI , CT and spinal x-ray all have shown degenerative changes to my spine. There is no evidence of recurrence. My CA125 is 13. The problem is I’m consumed with anxiety
I was diagnose with 2b Ovarian Cancer in April 22. I had surgery and 6 rounds of Chemo. I have a very supportive team . I have had an MRI , CT and spinal x-ray all have shown degenerative changes to my spine. There is no evidence of recurrence. My CA125 is 13. The problem is I’m consumed with anxiety
Hota
in
My Ovacome
8 months ago
I have my GP appt to discuss getting a diagnosis..... But do I ask for ANA tedt or referral to specialist???
Hi all, you were all so helpful when i first posted at the beginning of Feb! Finally the day is so close to discuss my possible lupus diagnosis (weds). I have took advice from your chats ,and written my symptoms down since start of Feb,and I'm ready to hopefully try to find a way forwards! But I guess
Hi all, you were all so helpful when i first posted at the beginning of Feb! Finally the day is so close to discuss my possible lupus diagnosis (weds). I have took advice from your chats ,and written my symptoms down since start of Feb,and I'm ready to hopefully try to find a way forwards! But I guess
Gingernat20
in
LUPUS UK
4 months ago
Bile acid malabsorption
I got diagnosed with bam over a year ago taking colesevelam for it i take 1 or 2 a day but it has my bowel movements all over the place its all or nothing and usually in a formed mush and sticky i try to eat healthy but just wondering if any one else has bowel movements like this i have ibs aswell and
I got diagnosed with bam over a year ago taking colesevelam for it i take 1 or 2 a day but it has my bowel movements all over the place its all or nothing and usually in a formed mush and sticky i try to eat healthy but just wondering if any one else has bowel movements like this i have ibs aswell and
Netbet22
in
IBS Network
5 months ago
Inverted Appendix and Stage 4 Endo
Hi all, I hoping someone has been through similar so I can connect with someone who has similar feelings. I've just been diagnosed with stage 4 endo. My womb, ovaries, tubes and appendix have all stuck to my bowels. I am in terrible pain when passing my bowels on a daily basis so I had a colonscopy
Hi all, I hoping someone has been through similar so I can connect with someone who has similar feelings. I've just been diagnosed with stage 4 endo. My womb, ovaries, tubes and appendix have all stuck to my bowels. I am in terrible pain when passing my bowels on a daily basis so I had a colonscopy
Nickyaa
in
Endometriosis UK
5 months ago
Diverticulitis
I am 75 years old. On Thursday morning I awoke with terrible abdominal pain and diarrhoea followed by heavy blood loss. I was very frightened. I went to A and E where I was looked after really well. They gave me painkillers and X-rays and a CT scan. I had diverticulitis and inflammation of sigmoid colon
I am 75 years old. On Thursday morning I awoke with terrible abdominal pain and diarrhoea followed by heavy blood loss. I was very frightened. I went to A and E where I was looked after really well. They gave me painkillers and X-rays and a CT scan. I had diverticulitis and inflammation of sigmoid colon
France21
in
Bowel Disease Support
5 months ago
Have'nt had a panic attacks in a long time but when it attacked it hit me hard for some reason.
hey everyone, So lastnight i decided to go out for a few drinks with a friend. Everything was fine at first, but then we left from the location that we were decided to go home while he's on his way to drop me home I feel a panic attack coming in but strong. I felt like I couldn't breathe and my heart
hey everyone, So lastnight i decided to go out for a few drinks with a friend. Everything was fine at first, but then we left from the location that we were decided to go home while he's on his way to drop me home I feel a panic attack coming in but strong. I felt like I couldn't breathe and my heart
Johnnie1234
in
Anxiety Support
26 days ago
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