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No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
7 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
7 months ago
Advanced prostate cancer
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Catdog1111
in
Advanced Prostate Cancer
7 months ago
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Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
7 months ago
Ugg, can we talk erections
Some questions for the
group
: 1. How much of this is the hormone
therapy
? Meaning, likely by now (more than 2mths on ADT) my testo has dropped very very far right? 2. Why doesnt Cialis help? 3. What is my outcome?
Some questions for the
group
: 1. How much of this is the hormone
therapy
? Meaning, likely by now (more than 2mths on ADT) my testo has dropped very very far right? 2. Why doesnt Cialis help? 3. What is my outcome?
Yzinger
in
Advanced Prostate Cancer
1 year ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
7 months ago
One post post decapeptyl injection
I've randomly started bleeding I'm one month post injection my pains have been so bad and ramped up this week even more to point I was being sick and now I been to toilet and I'm bleeding not loads but like start of period amount. But I'm confused I have pcos and can't even tell you last time I had a
I've randomly started bleeding I'm one month post injection my pains have been so bad and ramped up this week even more to point I was being sick and now I been to toilet and I'm bleeding not loads but like start of period amount. But I'm confused I have pcos and can't even tell you last time I had a
En89
in
Endometriosis UK
9 months ago
Life Expectancy
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
godhelpus
in
Advanced Prostate Cancer
7 months ago
Effect of Baseline T on T-Recovery Time
Here's a plot of % of Men who recover their baseline testosterone after stopping ADT (Lupron), as a function of ADT duration for two different groups: (A) men who had a
normal
baseline testosterone (red line), and (B) men who had a
low
baseline testosterone (green line). Increasing the
Here's a plot of % of Men who recover their baseline testosterone after stopping ADT (Lupron), as a function of ADT duration for two different groups: (A) men who had a
normal
baseline testosterone (red line), and (B) men who had a
low
baseline testosterone (green line). Increasing the
janebob99
in
Prostate Cancer Network
7 months ago
Testosterone Recovery for 50% of Men
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
janebob99
in
Prostate Cancer Network
7 months ago
Testosterone Recovery After ADT - Updated Plot
Thanks to Tall_Allen for providing lots of extra data for this plot: https://www.prostatecancer.news/2023/04/intermittent-adt.html You can easily extrapolate the curves to find out your recovery time. ADT duration of 3-9 months fall roughly on the same curve, and ADT of 18-24 roughly fall on the same
Thanks to Tall_Allen for providing lots of extra data for this plot: https://www.prostatecancer.news/2023/04/intermittent-adt.html You can easily extrapolate the curves to find out your recovery time. ADT duration of 3-9 months fall roughly on the same curve, and ADT of 18-24 roughly fall on the same
janebob99
in
Prostate Cancer Network
7 months ago
Help! on Pro-stap, tibolone HRT brought back endo pain!? Made me so unwell - anyone relate??
pro-stap monthly injections started November without HRT. Reduced lot of the endo pain (although made my stomach issues/sensitivity to food way worse). Decided to start tibolone HRT 10 weeks into the injections and it caused awful period/endo pain, spotting, flu type symptoms on and off. Only lasted
pro-stap monthly injections started November without HRT. Reduced lot of the endo pain (although made my stomach issues/sensitivity to food way worse). Decided to start tibolone HRT 10 weeks into the injections and it caused awful period/endo pain, spotting, flu type symptoms on and off. Only lasted
Flewks
in
Endometriosis UK
7 months ago
Can anyone help
Hi group. Ive been treated for underachieve thyroid for many years, mostly with Levothyroxine (current treatment) and for a brief period years ago Liothyronine (until it was stopped). My background is a healthcare professional and I understand the physiology side of the thyroid gland and associated
Hi group. Ive been treated for underachieve thyroid for many years, mostly with Levothyroxine (current treatment) and for a brief period years ago Liothyronine (until it was stopped). My background is a healthcare professional and I understand the physiology side of the thyroid gland and associated
SOT1512
in
Thyroid UK
11 months ago
Shingrix vaccine for immunosuppressed people aged 50+
I thought I would just post this from the gov.uk website because I have just a bit of struggle convincing our surgery that I was eligible, so maybe other people haven't been invited either. The full list is on chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://assets.publishing.service.gov.uk
I thought I would just post this from the gov.uk website because I have just a bit of struggle convincing our surgery that I was eligible, so maybe other people haven't been invited either. The full list is on chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://assets.publishing.service.gov.uk
Sharitone
in
PMRGCAuk
11 months ago
Testosterone recovery after stopping ADT - 3
This plot shows the % of men who recovered their original testosterone level after stopping Lupron ADT, plotted versus the time (months) after stopping ADT, for three different durations of ADT (4, 6-12, or 24 months). The curves show that a short course of ADT allows men to recover their testosterone
This plot shows the % of men who recovered their original testosterone level after stopping Lupron ADT, plotted versus the time (months) after stopping ADT, for three different durations of ADT (4, 6-12, or 24 months). The curves show that a short course of ADT allows men to recover their testosterone
janebob99
in
Prostate Cancer Network
7 months ago
Testosterone Recovery after stopping ADT -2
This plot shows the time after stopping Lupron ADT for the testosterone to recover to the original level for 50% of men, plotted versus Duration of ADT treatment (4 or 24 months). The longer the duration of ADT, the longer it takes to recover the original testosterone level, which makes sense. For
This plot shows the time after stopping Lupron ADT for the testosterone to recover to the original level for 50% of men, plotted versus Duration of ADT treatment (4 or 24 months). The longer the duration of ADT, the longer it takes to recover the original testosterone level, which makes sense. For
janebob99
in
Prostate Cancer Network
7 months ago
Testosterone Recovery after stopping ADT -1
Here's the first of four plots showing testosterone recovery after stopping Lupron ADT. The testosterone recovers quickest in the first 12 months, but then flattens out after that.
Here's the first of four plots showing testosterone recovery after stopping Lupron ADT. The testosterone recovers quickest in the first 12 months, but then flattens out after that.
janebob99
in
Prostate Cancer Network
7 months ago
Thoughts on Denosumab in my case
MO is suggesting Denosumab after my Dexa scan. Bone density normal in spine, osteopenia in right hip and osteoporosis on one part of left hip. I am wondering if with a -2.7 it is possible to control/improve with supplements and weight bearing exercises? What are you taking? Have added calcium. The
MO is suggesting Denosumab after my Dexa scan. Bone density normal in spine, osteopenia in right hip and osteoporosis on one part of left hip. I am wondering if with a -2.7 it is possible to control/improve with supplements and weight bearing exercises? What are you taking? Have added calcium. The
Hope49823
in
Advanced Prostate Cancer
7 months ago
PSMA PET Scan Frequency?
Hello forum members. This is my first post but have learned so much here, thanks to the contributors on this site. My husband’s last and only PSMA PET scan was 1.5 years ago showing 6 mets in small bones after PSA consistently rose a year after radiation. The standard ADT treatment was prescribed
Hello forum members. This is my first post but have learned so much here, thanks to the contributors on this site. My husband’s last and only PSMA PET scan was 1.5 years ago showing 6 mets in small bones after PSA consistently rose a year after radiation. The standard ADT treatment was prescribed
EatLovePray
in
Advanced Prostate Cancer
7 months ago
A Neophyte's Experience with a Gummy
Some of you might be interested in my gummy experience. I do not advocate anything here, but just want to share a new experience. Outside of four episodes in my eighty-four plus years, I have not used marijuana or other drugs beyond alcohol, coffee, maté from the Pampas of Argentina, and whatever uppers
Some of you might be interested in my gummy experience. I do not advocate anything here, but just want to share a new experience. Outside of four episodes in my eighty-four plus years, I have not used marijuana or other drugs beyond alcohol, coffee, maté from the Pampas of Argentina, and whatever uppers
Worked_the_World
in
Advanced Prostate Cancer
7 months ago
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