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PSA on the way up again
I am getting a little concerned about a increase in my PSA, and not just the increase, but also the increase in the rate of increase. Short history. Diagnosed March 2021 by MRI and biopsy Gleason 4 + 3, Stage T3B, ISUP 3 ADT (Zoladex) started June 2021 EBRT 60Gy in 20 fractions December 2021 Last
I am getting a little concerned about a increase in my PSA, and not just the increase, but also the increase in the rate of increase. Short history. Diagnosed March 2021 by MRI and biopsy Gleason 4 + 3, Stage T3B, ISUP 3 ADT (Zoladex) started June 2021 EBRT 60Gy in 20 fractions December 2021 Last
ParrotY
in
Prostate Cancer Network
7 months ago
Dutasteride Monotherapy is effective for Newly Diagnosed PCa men not on ADT
This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his
This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his
janebob99
in
Prostate Cancer Network
7 months ago
First time poster overwhelmed with symptoms and considering self-medicating with bovine adrenals & NDT. Asking for advice & recommendations
TLDR: First time poster diagnosed Hashimotos and POI, investigating IBS which is potentially also autoimmune cause. Fatigue, depression and anxiety are ruining my life. Low Adrenal Index Test results so considering self-medicating with Bovine Adrenals. High TSH and anti thyroid antibodies, but low-end-of-normal
TLDR: First time poster diagnosed Hashimotos and POI, investigating IBS which is potentially also autoimmune cause. Fatigue, depression and anxiety are ruining my life. Low Adrenal Index Test results so considering self-medicating with Bovine Adrenals. High TSH and anti thyroid antibodies, but low-end-of-normal
KayNaomi
in
Thyroid UK
7 months ago
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Light Therapy Celeste
Photopharmics is getting ready to recruit for phase 3. For those interested: https://photopharmics.com/innovative-research-inclusive-trials-and-new-funding-drives-hope-for-people-with-parkinsons-disease/
Photopharmics is getting ready to recruit for phase 3. For those interested: https://photopharmics.com/innovative-research-inclusive-trials-and-new-funding-drives-hope-for-people-with-parkinsons-disease/
Pegcity
in
Cure Parkinson's
11 months ago
What Now?
So I had my laparoscopy last May, confirmed endo, coil fitted. Pain returned after a few months. In November I was put on Zoladex injections with Tibilone HRT tablets, this helped the pain a lot and reduced it to a few times within the 3 month period of being on it. Now the last 2 weeks the pain has
So I had my laparoscopy last May, confirmed endo, coil fitted. Pain returned after a few months. In November I was put on Zoladex injections with Tibilone HRT tablets, this helped the pain a lot and reduced it to a few times within the 3 month period of being on it. Now the last 2 weeks the pain has
Mummaamber
in
Endometriosis UK
7 months ago
High PSA upon diagnosis, treatment , and outcome
Hello, Diagnosed 9 months ago with Gleason 7 unfavorable… 2 4+3 ,2 3+4, and 1 3+3 ..on one side only ..I guess my high PSA score made it unfavorable , PSA 18. As a result had aggressive tri modality treatment .. brachytherapy seeds, 15 linac radiation sessions, and 9 months o ADT ..just stopped
Hello, Diagnosed 9 months ago with Gleason 7 unfavorable… 2 4+3 ,2 3+4, and 1 3+3 ..on one side only ..I guess my high PSA score made it unfavorable , PSA 18. As a result had aggressive tri modality treatment .. brachytherapy seeds, 15 linac radiation sessions, and 9 months o ADT ..just stopped
Yokohama2023
in
Prostate Cancer Network
7 months ago
TSH Level
hiya( again 😏) Got a call from the receptionist on Wednesday my TSH level is 5 and I have been advised to stop my Carbimazole 5mg immediately, she was unable to offer any other advise other than I’m to continue having my bloods every 4 weeks . Am I correct does the level of 5 now bring me into the
hiya( again 😏) Got a call from the receptionist on Wednesday my TSH level is 5 and I have been advised to stop my Carbimazole 5mg immediately, she was unable to offer any other advise other than I’m to continue having my bloods every 4 weeks . Am I correct does the level of 5 now bring me into the
Forumjunkie
in
Thyroid UK
7 months ago
throbbing lower leg
hi all, New here I’ve had endo for 15 years it eased up and I thought it had gone when I had my daughter 11 years ago but when she was 8 it came back with vengeance. Had a laparoscopy and encision surgery in Oct 2023 pain eased up for 3 months then came back yet again so now they have started me on
hi all, New here I’ve had endo for 15 years it eased up and I thought it had gone when I had my daughter 11 years ago but when she was 8 it came back with vengeance. Had a laparoscopy and encision surgery in Oct 2023 pain eased up for 3 months then came back yet again so now they have started me on
DanDan1991
in
Endometriosis UK
7 months ago
First MO visit
Prostectomy in 2017 and radiation in 2020 with no further treatment. PSMA test in November 2023 was negative with PSA of 0.14 at that time. My PSA has now increased to 0.34. I have my first visit with an MO in a couple weeks. Any suggestions or hints as to what to expect for treatments following
Prostectomy in 2017 and radiation in 2020 with no further treatment. PSMA test in November 2023 was negative with PSA of 0.14 at that time. My PSA has now increased to 0.34. I have my first visit with an MO in a couple weeks. Any suggestions or hints as to what to expect for treatments following
RedBird713
in
Advanced Prostate Cancer
7 months ago
Care Home response
Please can I thank everyone who sent a response to my original post. It is encouraging to hear from so many of you who have similar stories. My husband is responding well to the care home and the staff are lovely. I have had a lot of support from the health professionals , consultant, physio, speech
Please can I thank everyone who sent a response to my original post. It is encouraging to hear from so many of you who have similar stories. My husband is responding well to the care home and the staff are lovely. I have had a lot of support from the health professionals , consultant, physio, speech
Wybert
in
PSP Association
11 months ago
Zoladex and bleeding
So I was on Decapeptyl for a few months last year, a month without HRT and a couple with. I stopped using it because it was causing me headaches and was switched to Zoladex alongside HRT. For the first 4 injections it was fine, it stopped my periods and I was doing ok, although my moods have got slightly
So I was on Decapeptyl for a few months last year, a month without HRT and a couple with. I stopped using it because it was causing me headaches and was switched to Zoladex alongside HRT. For the first 4 injections it was fine, it stopped my periods and I was doing ok, although my moods have got slightly
x_b_x
in
Endometriosis UK
7 months ago
weight gain with low TSH?
Hi! Just got my blood work back, normal range T3 and T4 but bdl for TSH. Feeling a little sluggish and tired, no tolerance to COLD, getting sick a lot and consistently gaining weight over the past 4 months. Just some background, I got my thyroid removed 2 years ago due to graves disease. I've been
Hi! Just got my blood work back, normal range T3 and T4 but bdl for TSH. Feeling a little sluggish and tired, no tolerance to COLD, getting sick a lot and consistently gaining weight over the past 4 months. Just some background, I got my thyroid removed 2 years ago due to graves disease. I've been
KymmyLo
in
Thyroid UK
7 months ago
My experience with mental health and First Episode Psychosis.
The way in which acute Psychosis can affect your life is so overwhelming that I thought I’d write a piece to spread awareness and combat the stigmatization that this symptom of mental health illness has in our society. I have had a few years of struggles with anxiety, panic attacks and depression,
The way in which acute Psychosis can affect your life is so overwhelming that I thought I’d write a piece to spread awareness and combat the stigmatization that this symptom of mental health illness has in our society. I have had a few years of struggles with anxiety, panic attacks and depression,
shawshankred
in
Anxiety and Depression Support
7 months ago
Extremely interesting....
The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629976/
The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629976/
Easylover
in
Thyroid UK
11 months ago
Combination therapy T4 + T3
Hi, since 2 weeks I started to take 10 mcg T3/ 2 days on top of my daily levothyroxine. I remember my periodic cycle was 24 days instead of 28 days when TSH was rising before. Today I was surprised to get my period at d23?! I am confused again. Was expecting the opposite.
Hi, since 2 weeks I started to take 10 mcg T3/ 2 days on top of my daily levothyroxine. I remember my periodic cycle was 24 days instead of 28 days when TSH was rising before. Today I was surprised to get my period at d23?! I am confused again. Was expecting the opposite.
Balou23
in
Thyroid UK
11 months ago
NGS Test/Next-Generation Sequencing Important to have done.
Hello friends. I just wanted to make sure that if you are able to have this testing done, it is really important for your health and treatments that are given for your TYPE of BC. I was dx in 2016 and MBC in 2019. Ibrance and Fasoldex lated aobut 2 years. I was and still am ER/PR + and HER2low, but
Hello friends. I just wanted to make sure that if you are able to have this testing done, it is really important for your health and treatments that are given for your TYPE of BC. I was dx in 2016 and MBC in 2019. Ibrance and Fasoldex lated aobut 2 years. I was and still am ER/PR + and HER2low, but
Hopeful4Cure
in
SHARE Metastatic Breast Cancer
7 months ago
What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
Hello, I have touched on this subject before, but it is something that is nagging at me and giving me some sleepless nights. My husband’s bio is updated for reference. At one year post prostatectomy with Stage 3b, he rose from 0.06 to 0.273 in three mos. At psa of 0.16 , a PSMA scan showed three sub
103532
in
Advanced Prostate Cancer
6 months ago
Recording available for NoSilverBullet interview of Dr Wayne Markman, CEO of SYMBYX, on "Light therapy for Parkinson's".
Thank you to Dr Wayne Markman for this very detailed interview on the topic of "Light Therapy for Parkinson's". It was a fascinating presentation with an excellent Q&A afterwards. It is available now on our YouTube channel so please take a look: https://youtu.be/E9XSIzblucc?feature=shared It is also
Thank you to Dr Wayne Markman for this very detailed interview on the topic of "Light Therapy for Parkinson's". It was a fascinating presentation with an excellent Q&A afterwards. It is available now on our YouTube channel so please take a look: https://youtu.be/E9XSIzblucc?feature=shared It is also
Michel0220
in
Cure Parkinson's
11 months ago
Are we on the right track?
Hi All, My husband, Pat (61) was diagnosed in late February with low grade metastatic PC. Gleason 9 grade 5. PSA 32. In a few small pelvic lymph nodes and a couple pelvic lesions. No other spread. PSMA pet scan detected this. We are working with a team and when we were told his diagnosis from his
Hi All, My husband, Pat (61) was diagnosed in late February with low grade metastatic PC. Gleason 9 grade 5. PSA 32. In a few small pelvic lymph nodes and a couple pelvic lesions. No other spread. PSMA pet scan detected this. We are working with a team and when we were told his diagnosis from his
Kathyford
in
Advanced Prostate Cancer
4 months ago
Hormonal treatment for Endometriosis
I had an appointment with a specialist recently and I expressed the desire to have diagnostic laparoscopy for endometriosis. The specialist recommended that I try taking hormones in the meantime to see if that helps with pain management. He said that by taking hormones I could control my period and choose
I had an appointment with a specialist recently and I expressed the desire to have diagnostic laparoscopy for endometriosis. The specialist recommended that I try taking hormones in the meantime to see if that helps with pain management. He said that by taking hormones I could control my period and choose
Tigerlily34
in
Women's Health
7 months ago
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