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Dutasteride Monotherapy is effective for Newly Diagnosed PCa men not on ADT

janebob99 profile image
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This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT.

Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his PSA dropped from 43 to 3 (a 93% drop)!

About 15% of men in Group A are non-responders, and about 35-40% of men in Group B are non-responders to Dutasteride monotherapy.

ncbi.nlm.nih.gov/pmc/articl...

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janebob99
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maley2711 profile image
maley2711

You may want to consider more studies......

mayoclinic.org/drugs-supple....

janebob99 profile image
janebob99 in reply to maley2711

THANKS !

maley2711 profile image
maley2711 in reply to janebob99

It is never a bad idea to check out TA's blogsite for his research findings on various topics.....

here is one article.....

prostatecancer.news/2023/04...

the search engine works very well, as well as a long list of clickable topics on the right side. He has been researching for many years..

I guess finasteride and dutasteride have been used primarily to reduce prostate size.....and I remembered the warning about "false" PSA readings with finasteride.

janebob99 profile image
janebob99

Thanks.

His website is a wealth of knowledge.

Do you have any concerns about the black label warning on Dutasteride?

RodriguezJ profile image
RodriguezJ

This suggests that while dutasteride can be very effective, its efficacy varies significantly among individuals, especially those with newly diagnosed PCa.

But actually, the more reliable is the pharmacy, the better and more effective is the medication, so choose reliable pharmacies, such as - fast-supply24.com

janebob99 profile image
janebob99 in reply to RodriguezJ

Yes, you are correct. About 15% of men who don't have prostate cancer are non-responders, while 30% of men who do have prostate cancer are non-responders. Perhaps that's why it's not prescribed more often...

Bob

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