Dutasteride Monotherapy is effective for Newly Diagnosed PCa men not on ADT

[janebob99]

This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT.

Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his PSA dropped from 43 to 3 (a 93% drop)!

About 15% of men in Group A are non-responders, and about 35-40% of men in Group B are non-responders to Dutasteride monotherapy.

ncbi.nlm.nih.gov/pmc/articl...

[maley2711]

You may want to consider more studies......

mayoclinic.org/drugs-supple....

[janebob99 in reply to maley2711]

THANKS !

[maley2711 in reply to janebob99]

It is never a bad idea to check out TA's blogsite for his research findings on various topics.....

here is one article.....

prostatecancer.news/2023/04...

the search engine works very well, as well as a long list of clickable topics on the right side. He has been researching for many years..

I guess finasteride and dutasteride have been used primarily to reduce prostate size.....and I remembered the warning about "false" PSA readings with finasteride.

[janebob99]

Thanks.

His website is a wealth of knowledge.

Do you have any concerns about the black label warning on Dutasteride?