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Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
janebob99
in
Prostate Cancer Network
4 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
janebob99
in
Advanced Prostate Cancer
4 months ago
Early Results from Transdermal Estrogen PATCH trial
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Advanced Prostate Cancer
4 months ago
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Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
4 months ago
propranolol
hello. I had an awful anxiety attack that started on Sunday. I used to have them in the past as well as depression but taking sertraline 3 times a week helped keep things under control. I’m menopausal and on HRT and I think it’s related. I spoke to a GP who prescribed propranolol for the physical symptoms
hello. I had an awful anxiety attack that started on Sunday. I used to have them in the past as well as depression but taking sertraline 3 times a week helped keep things under control. I’m menopausal and on HRT and I think it’s related. I spoke to a GP who prescribed propranolol for the physical symptoms
wdwfan1973
in
Anxiety Support
1 year ago
Estrogen ADT vs Lupron ADT
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Silly Questions??
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
TommyCarz2
in
Advanced Prostate Cancer
4 months ago
Allergic reaction to Doxil, my first ever chemo infusion
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
penpen18
in
SHARE Metastatic Breast Cancer
4 months ago
up date
hi I will try and not write to much The nerve pain in my leg, I wrote about months ago, was caused by my hip Now going to have a hip replacement, followed by knee replacement and maybe other hip I am having these done at my local hospital and will bridge with clexane if still on Warfarin I am also
hi I will try and not write to much The nerve pain in my leg, I wrote about months ago, was caused by my hip Now going to have a hip replacement, followed by knee replacement and maybe other hip I am having these done at my local hospital and will bridge with clexane if still on Warfarin I am also
daisyd
in
Hughes Syndrome APS Forum
11 months ago
Red nose after Raynaud’s diagnosis
Morning all 😀 I was diagnosed with Raynaud’s last winter and have since been experiencing horrible nose and cheek issues. m when I get hot or if I eat hot food my nose and cheeks pulsate and go bright red. It then goes almost back to normal as I cool down!! this has left me with a redder than normal
Morning all 😀 I was diagnosed with Raynaud’s last winter and have since been experiencing horrible nose and cheek issues. m when I get hot or if I eat hot food my nose and cheeks pulsate and go bright red. It then goes almost back to normal as I cool down!! this has left me with a redder than normal
Tor1972
in
Scleroderma & Raynaud's UK (SRUK)
1 year ago
Guidelines Recommend Mindfulness-Based Interventions for Anxiety and Depression During Cancer Treatment
Adults with cancer can benefit from mindfulness-based interventions and other therapies to manage symptoms of anxiety and depression. Guidelines now recommend mindfulness-based interventions such as meditation and mindful movement to manage anxiety and depression in adults with cancer. In particular
Adults with cancer can benefit from mindfulness-based interventions and other therapies to manage symptoms of anxiety and depression. Guidelines now recommend mindfulness-based interventions such as meditation and mindful movement to manage anxiety and depression in adults with cancer. In particular
Katie-LMHC-Artist
in
CLL Support
9 months ago
Femseven conti patches
Hi,Has anyone been prescribed femseven conti patches? I've been prescribed these by the nurse at the GP surgery as an alternative to evorel as they were making me bleed and my anxiety was really bad. I've read on the packet they could increase fibroids so not sure I should be taking them. I'm on 3
Hi,Has anyone been prescribed femseven conti patches? I've been prescribed these by the nurse at the GP surgery as an alternative to evorel as they were making me bleed and my anxiety was really bad. I've read on the packet they could increase fibroids so not sure I should be taking them. I'm on 3
Sheep2
in
Endometriosis UK
1 year ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
4 months ago
Advanced prostate cancer
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Catdog1111
in
Advanced Prostate Cancer
4 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
4 months ago
If PSA is Suppressed by Doublet ADT, Will Salvage IMRT Cause a PSA Rise?
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
103532
in
Advanced Prostate Cancer
3 months ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
4 months ago
living with panic disorder- any tips?
I was diagnosed with panic disorder in mid 2022, it was a sudden occurance that traumatized me I fear for life. I had panic attacks that lasted from the moment I woke up to the minute I fell asleep, sometimes waking from them which lasted weeks before I looked for professional help. I went to intensive
I was diagnosed with panic disorder in mid 2022, it was a sudden occurance that traumatized me I fear for life. I had panic attacks that lasted from the moment I woke up to the minute I fell asleep, sometimes waking from them which lasted weeks before I looked for professional help. I went to intensive
Takeabath
in
Anxiety and Depression Support
10 months ago
Life Expectancy
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
godhelpus
in
Advanced Prostate Cancer
4 months ago
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